| Description : |
This gene encodes a protein containing RING-type and C3H1-type zinc finger motifs. The encoded protein recognizes and binds to a constitutive decay element (CDE) in the 3' UTR of mRNAs, leading to mRNA deadenylation and degradation. Alternative splicing results in multiple transcript variants. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
125.6 kDa |
| AA Sequence : |
MPVQAPQWTDFLSCPICTQTFDETI RKPISLGCGHTVCKMCLNKLHRKAC PFDQTTINTDIELLPVNSALLQLVG AQVPEQQPITLCSGVEDTKHYEEAK KCVEELALYLKPLSSARGVGLNSTT QSVLSRPMQRKLVTLVHCQLVEEEG RIRAMRAARSLGERTVTELILQHQN PQQLSSNLWAAVRARGCQFLGPAMQ EEALKLVLLALEDGSALSRKVLVLF VVQRLEPRFPQASKTSIGHVVQLLY RASCFKVTKRDEDSSLMQLKEEFRT YEALRREHDSQIVQIAMEAGLRIAP DQWSSLLYGDQSHKSHMQSIIDKLQ TPASFAQSVQELTIALQRTGDPANL NRLRPHLELLANIDPSPDAPPPTWE QLENGLVAVRTVVHGLVDYIQNHSK KGADQQQPPQHSKYKTYMCRDMKQR GGCPRGASCTFAHSQEELEKFRKMN KRLVPRRPLSASLGQLNEVGLPSAA ILPDEGAVDLPSRKPPALPNGIVST GNTVTQLIPRGTDPSYDSSLKPGKI DHLSSSAPGSPPDLLESVPKSISAL PVNPHSIPPRGPADLPPMPVTKPLQ MVPRGSQLYPAQQTDVYYQDPRGAA PPFEPAPYQQGMYYTPPPQCVSRFV RPPPSAPEPAPPYLDHYPPYLQERV VNSQYGTQPQQYPPIYPSHYDGRRV YPAPSYTREEIFRESPIPIEIPPAA VPSYVPESRERYQQIESYYPVAPHP TQIRPSYLREPPYSRLPPPPQPHPS LDELHRRRKEIMAQLEERKVISPPP FAPSPTLPPTFHPEEFLDEDLKVAG KYKGNDYSQYSPWSCDTIGSYIGTK DAKPKDVVAAGSVEMMNVESKGMRD QRLDLQRRAAETSDDDLIPFGDRPT VSRFGAISRTSKTIYQGAGPMQAMA PQGAPTKSINISDYSPYGTHGGWGA SPYSPHQNIPSQGHFSERERISMSE VASHGKPLPSAEREQLRLELQQLNH QISQQTQLRGLEAVSNRLVLQREAN TLAGQSQPPPPPPPKWPGMISSEQL SLELHQVEREIGKRTRELSMENQCS LDMKSKLNTSKQAENGQPEPQNKVP AEDLTLTFSDVPNGSALTQENISLL SNKTSSLNLSEDPEGGGDNNDSQRS GVTPSSAPTRTRPLEQKLISEEDLA ANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
