rnd2 Protein, Rho family GTPase 2


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Official Full Name Rho family GTPase 2
Background This gene encodes a member of the Rho GTPase family, whose members play a key role in the regulation of actin cytoskeleton organization in response to extracellular growth factors. This particular family member has been implicated in the regulation of neuronal morphology and endosomal trafficking. The gene localizes to chromosome 17 and is the centromeric neighbor of the breast-ovarian cancer susceptibility gene BRCA1.
Synonyms RND2; Rho family GTPase 2; ARHN, ras homolog gene family, member N; rho-related GTP-binding protein RhoN; Rho7; RhoN; ARHN; Rho 7; Rho N; Rho related GTP-binding protein RhoN; Rho-related GTP-binding protein Rho7; Rnd 2; RND2_HUMAN; GTP-binding protein Rho7; ras homolog gene family, member N
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • MYC/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Rnd2-647M Recombinant Mouse Rnd2 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Human RND2-2313HCL Recombinant Human RND2 293 Cell Lysate HEK293 N/A
    Human RND2-2331H Recombinant Human RND2, GST-tagged E.coli GST
    Human RND2-699H Recombinant Human RND2 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Rhesus Macaque RND2-3918R Recombinant Rhesus monkey RND2 Protein, His-tagged Mammalian Cell His
    Chicken RND2-4545C Recombinant Chicken RND2 Mammalian Cell His
    Zebrafish RND2-4341Z Recombinant Zebrafish RND2 Mammalian Cell His

    rnd2 involved in several pathways and played different roles in them. We selected most pathways rnd2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with rnd2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    rnd2 has several biochemical functions, for example, GTP binding, GTPase activity, protein N-terminus binding. Some of the functions are cooperated with other proteins, some of the functions could acted by rnd2 itself. We selected most functions rnd2 had, and list some proteins which have the same functions with rnd2. You can find most of the proteins on our site.

    Function Related Protein
    GTPase activity GPN1; RAB12; GSPT1L; DNM3; GNAI2A; RAB5AA; RAB6A; GNAO1; GNL2; GNB5
    protein N-terminus binding VWF; EIF5A; RASSF1; RND2; ERCC4; ZWINT; ERCC2; ACOX1; GLRX; KCNB1
    protein binding UBE2Q1; HOMEZ; GZMM; TAF15; DRG1; RGS7BP; SPATC1; BCAR1; FAT4; ZFP110

    rnd2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with rnd2 here. Most of them are supplied by our site. Hope this information will be useful for your research of rnd2.


    Fichter, CD; Gudernatsch, V; et al. ErbB targeting inhibitors repress cell migration of esophageal squamous cell carcinoma and adenocarcinoma cells by distinct signaling pathways. JOURNAL OF MOLECULAR MEDICINE-JMM 92:1209-1223(2014).
    Sayyah, J; Bartakova, A; et al. The Ras-related Protein, Rap1A, Mediates Thrombin-stimulated, Integrin-dependent Glioblastoma Cell Proliferation and Tumor Growth. JOURNAL OF BIOLOGICAL CHEMISTRY 289:17689-17698(2014).

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