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Official Full Name ring finger protein 125, E3 ubiquitin protein ligase
Background This gene encodes a novel E3 ubiquitin ligase that contains an N-terminal RING finger domain. The encoded protein may function as a positive regulator in the T-cell receptor signaling pathway.
Synonyms RNF125; ring finger protein 125, E3 ubiquitin protein ligase; ring finger protein 125; E3 ubiquitin-protein ligase RNF125; FLJ20456; T-cell RING activation protein 1; T-cell ring protein identified in activation screen; TRAC1; TRAC-1; MGC21737
    • Species :
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human RNF125-2119H Recombinant Human RNF125 Protein (1-232 aa), GST-tagged E.coli GST
    Human RNF125-545HCL Recombinant Human RNF125 lysate HEK293 N/A
    Mouse RNF125-14294M Recombinant Mouse RNF125 Protein Mammalian Cell His
    Cynomolgus Monkey RNF125-859C Recombinant Cynomolgus RNF125 Protein, His-tagged Mammalian Cell His

    RNF125 involved in several pathways and played different roles in them. We selected most pathways RNF125 participated on our site, such as RIG-I-like receptor signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with RNF125 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    RIG-I-like receptor signaling pathway IFNA16; CXCL10; IFNA21; IFNA4; Ifna15; IKBKB; Ifna11; IFNK; NFKBIAA; TNF

    RNF125 has several biochemical functions, for example, ligase activity, ubiquitin-protein transferase activity, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RNF125 itself. We selected most functions RNF125 had, and list some proteins which have the same functions with RNF125. You can find most of the proteins on our site.

    Function Related Protein
    ligase activity CMTM2A; CDC34A; HERC3; ZNRF2B; RNF135; CBL; TTLL4; KCNG4; RNF213; TRIM9
    ubiquitin-protein transferase activity TRIM56; SIAH1A; FBXO9; ZYG11B; RNF5; TRIM23; TRIM62; TRAF3; MDM2; CBLL1
    zinc ion binding ADAMTS15A; ZDHHC16; SNCA; LHX8; CPA4; ADH6; RXRB; PCGF1; LIMCH1A; APOBEC2B

    RNF125 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RNF125 here. Most of them are supplied by our site. Hope this information will be useful for your research of RNF125.


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