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Official Full Name ring finger protein 5, E3 ubiquitin protein ligase
Background The protein encoded by this gene contains a RING finger, which is a motif known to be involved in protein-protein interactions. This protein is a membrane-bound ubiquitin ligase. It can regulate cell motility by targeting paxillin ubiquitination and altering the distribution and localization of paxillin in cytoplasm and cell focal adhesions.
Synonyms RNF5; RMA1; RING5; ring finger protein 5, E3 ubiquitin protein ligase; E3 ubiquitin-protein ligase RNF5; protein G16; ram1 homolog
    • Species :
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human RNF5-2347H Recombinant Human RNF5, GST-tagged E.coli GST
    Human RNF5-549HCL Recombinant Human RNF5 lysate HEK293 N/A
    Human RNF5-609H Recombinant Human RNF5 Mammalian Cell His
    Mouse RNF5-14352M Recombinant Mouse RNF5 Protein Mammalian Cell His
    Rat RNF5-5086R Recombinant Rat RNF5 Protein Mammalian Cell His
    Rhesus Macaque RNF5-3946R Recombinant Rhesus monkey RNF5 Protein, His-tagged Mammalian Cell His

    rnf5 involved in several pathways and played different roles in them. We selected most pathways rnf5 participated on our site, such as Protein processing in endoplasmic reticulum, which may be useful for your reference. Also, other proteins which involved in the same pathway with rnf5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Protein processing in endoplasmic reticulum MAPK8B; BAG1; RNF5; RRBP1B; UBE2D4; HSPH1; VCP; SEC61AL2; GSBP9; NGLY1

    rnf5 has several biochemical functions, for example, ligase activity, protein binding, ubiquitin protein ligase activity involved in ERAD pathway. Some of the functions are cooperated with other proteins, some of the functions could acted by rnf5 itself. We selected most functions rnf5 had, and list some proteins which have the same functions with rnf5. You can find most of the proteins on our site.

    Function Related Protein
    ligase activity UBE3B; UFL1; MYLIP; LNX1; TMEM129; ACSF2; TRIM32; TRIML2; SIAH2L; STUB1
    protein binding SYT6; RNF13; ANKFY1; E4F1; ARL2BP; MUC7; TMEM231; PLSCR1; GPR177; CXCL9
    ubiquitin protein ligase activity involved in ERAD pathway RNF185; STUB1; SYVN1; TMEM129; AMFR; RNF5; TRIM25; PARK2
    ubiquitin-protein transferase activity RNF6; PRP19; UHRF2; RNF10; TRIM68; ZNRF3; TRAF2; UBR3; RNF43; RNF41
    zinc ion binding PCGF1; ZDHHC18; ZDHHC15A; RNF217; TRIM55; ERAP1; DTX3; PHF21A; MLL1; RNF113B

    rnf5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with rnf5 here. Most of them are supplied by our site. Hope this information will be useful for your research of rnf5.

    UBE2D3; UBE2E3; UBE2D1; UBE2E2

    Qin, Y; Zhou, MT; et al. RNF26 Temporally Regulates Virus-Triggered Type I Interferon Induction by Two Distinct Mechanisms. PLOS PATHOGENS 10:-(2014).
    Bernasconi, R; Galli, C; et al. Autoadaptive ER-Associated Degradation Defines a Preemptive Unfolded Protein Response Pathway. MOLECULAR CELL 52:783-793(2013).

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