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Official Full Name roundabout, axon guidance receptor, homolog 2 (Drosophila)
Background The protein encoded by this gene belongs to the ROBO family, part of the immunoglobulin superfamily of proteins that are highly conserved from fly to human. The encoded protein is a transmembrane receptor for the slit homolog 2 protein and functions in axon guidance and cell migration. Mutations in this gene are associated with vesicoureteral reflux, characterized by the backward flow of urine from the bladder into the ureters or the kidney. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
Synonyms ROBO2; roundabout, axon guidance receptor, homolog 2 (Drosophila); SAX3; roundabout homolog 2;
    • Species :
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • HEK293T
    • Human Cell
    • Mammalian Cell
    • Tag :
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ROBO2-2779H Recombinant Human ROBO2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Robo2-5567M Recombinant Mouse Robo2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human ROBO2-1225HCL Recombinant Human ROBO2 cell lysate Human Cell N/A
    Zebrafish ROBO2-9171Z Recombinant Zebrafish ROBO2 Mammalian Cell His

    robo2 involved in several pathways and played different roles in them. We selected most pathways robo2 participated on our site, such as Axon guidance, which may be useful for your reference. Also, other proteins which involved in the same pathway with robo2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Axon guidance NCK1; KCNQ2; EFNA1; SCN9A; NFATC4; RNF8; RAC1; NEFLB; SEMA4B; FGFR1B

    robo2 has several biochemical functions, for example, axon guidance receptor activity, identical protein binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by robo2 itself. We selected most functions robo2 had, and list some proteins which have the same functions with robo2. You can find most of the proteins on our site.

    Function Related Protein
    axon guidance receptor activity SEMA5A; ROBO2; GFRA3; ROBO1; EPHB3; EPHB1; EPHA7
    identical protein binding NDE1; BRAP; HOOK2; DES; SOX10; TRADD; TTC32; COL1A2; SH2B2; GPSM2
    protein binding KIAA0141; RBM25; ATMIN; FBXW9; KIAA0408; AKR7A3; SDCBP; FAM58A; TPSAB1; MRPL11

    robo2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with robo2 here. Most of them are supplied by our site. Hope this information will be useful for your research of robo2.


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