RPS5
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Official Full Name
ribosomal protein S5
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Background
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S7P family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. -
Synonyms
RPS5; ribosomal protein S5; 40S ribosomal protein S5; S5; 40S ribosomal protein S5 N terminally processed; RPS 5; RS5;
- Involved Pathway
- Protein Function
- Interacting Protein
RPS5 involved in several pathways and played different roles in them. We selected most pathways RPS5 participated on our site, such as Ribosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with RPS5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ribosome | RPL37A;RPL36A-HNRNPH2;RPL8;RPL3;RPS19;RPS26;RPS20;RPL36A;MRPL3 |
RPS5 has several biochemical functions, for example, RNA binding, mRNA binding, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RPS5 itself. We selected most functions RPS5 had, and list some proteins which have the same functions with RPS5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA binding | RPL31;EXOSC3;RPL3;ZFML;DPPA5A;BICC1;EIF4B;ASCC1;MCTS2 |
| mRNA binding | ZFP36L1;TSN;RBM8A;NUDT21;RBPMS2B;PIWIL1;RBFOX2;DCP1B;RBM4 |
| poly(A) RNA binding | RPS19;REXO4;YWHAE;MYO18A;NOC3L;H1F0;NKRF;LSM14A;FAM120A |
| rRNA binding | RPF2;RPS18;KDM2B;RPS11;MTERFD2;MRPS17;RPS4X;DIEXF;MRPS7 |
| structural constituent of ribosome | RPS15;MRPL46;RPL28;RPS26;RPS26L;DAP3;RPS16;RPL31;RPL10L |
RPS5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RPS5 here. Most of them are supplied by our site. Hope this information will be useful for your research of RPS5.
NFKB2; RELB; MAP3K14; TBK1; IKBKG; MLH1; midostaurin; Srp72; Smad6; NS; GABARAP; ESR1; NS; US11; NPM1; VCAM1
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