RUNX1T1

Official Full Name

runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
Overview

Vibrio cholerae is a motile gram negative curved rod shaped bacterium with a polar flagellum that causes cholera in humans. Serological typing of Vibrio cholerae is based on its O somatic antigens and it is classified in to more than 200 types. Of these,
Synonyms

RUNX1T1; runt-related transcription factor 1; translocated to, 1 (cyclin D-related); AML1T1, CBFA2T1, core binding factor, runt domain, alpha subunit 2; translocated to, 1; cyclin D related; protein CBFA2T1; CDR; ETO; MTG8; ZMYND2; eight twenty one prote;

Type

Recombinant Proteins
Cell & Tissue Lysates

Species

Chicken
Human
Mouse
Zebrafish

Source

E.coli
HEK293
HEK293T
Mammalian Cell

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	RUNX1T1-2472H	Recombinant Human RUNX1T1, His-tagged	E.coli	His	1-351aa	$319 / 25μg
Human	RUNX1T1-2110HCL	Recombinant Human RUNX1T1 293 Cell Lysate	HEK293	Non		Inquiry
Human	RUNX1T1-2109HCL	Recombinant Human RUNX1T1 293 Cell Lysate	HEK293	Non		Inquiry
Human	RUNX1T1-1148H	Recombinant Human RUNX1T1 protein, His&Myc-tagged	E.coli	His&Myc	1-604aa	Inquiry
Human	RUNX1T1-701H	Recombinant Human RUNX1T1 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc&DDK		Inquiry
Human	RUNX1T1-2942H	Recombinant Human RUNX1T1 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc&DDK		Inquiry
Mouse	Runx1t1-784M	Recombinant Mouse Runx1t1 Protein, MYC/DDK-tagged	HEK293T	Myc&DDK		Inquiry
Zebrafish	RUNX1T1-4600Z	Recombinant Zebrafish RUNX1T1	Mammalian Cell	His		Inquiry
Chicken	RUNX1T1-6309C	Recombinant Chicken RUNX1T1	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

RUNX1T1 involved in several pathways and played different roles in them. We selected most pathways RUNX1T1 participated on our site, such as Pathways in cancer, Transcriptional misregulation in cancer, Acute myeloid leukemia, which may be useful for your reference. Also, other proteins which involved in the same pathway with RUNX1T1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Pathways in cancer	PPARD;BCL2L1;NTRK1;HDAC2;MAPK3;HSP90AB1;HHIP;PLCB3;MET
Transcriptional misregulation in cancer	ATM;HDAC1;SS18;BCL2A1;BCL6;PBX1;MDM2;PPARG;SIX1
Acute myeloid leukemia	STAT3;PIK3R1;PPARD;PIK3R2;TCF7L2;AKT3;PML;RARA;SPI1

RUNX1T1 has several biochemical functions, for example, DNA binding, identical protein binding, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RUNX1T1 itself. We selected most functions RUNX1T1 had, and list some proteins which have the same functions with RUNX1T1. You can find most of the proteins on our site.

Function	Related Protein
DNA binding	MBD3A;ZC3H3;TRIM28;ZNF521;TADA2B;ZNF707;ETV5B;ZNF473;HIST1H2BM
identical protein binding	NEFL;TMEM173;SRI;IL12B;LRRK1;NUDT16;VWA2;KRTAP10-5;SNRNP200
metal ion binding	LHX6;ZFP239;AKAP8L;FLYWCH1;RBAK;PHF20B;CHORDC1;COL18A1;ZFP35
protein binding	SH2D2A;PPARGC1A;PRPF3;ZFYVE9;PRL2C2;WAS;SORCS1;CORO1A;EPOR
transcription corepressor activity	CREG1;NCOR1;SSX2;ZMYND11;KCNIP3;ENO1;LOXL2;NEUROD2;MECP2
transcription factor activity, sequence-specific DNA binding	PBX3B;MXD1;SOX11A;ZIC1;RREB1;RORAB;FOXD3;RFX1A;NR5A5

RUNX1T1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RUNX1T1 here. Most of them are supplied by our site. Hope this information will be useful for your research of RUNX1T1.

NCOR2; SP1; NCOR1; PSMD11; OTUD4; ZBTB16; HDAC1; ZNF652; THRAP3; LPXN; ATN1; C19orf57; CEP170P1; TAF9B

Research Area

Fu, R; Liu, H; et al. Osteoblast inhibition by chemokine cytokine ligand3 in myeloma-induced bone disease. CANCER CELL INTERNATIONAL 14:-(2014).

Kook, SH; Jeon, YM; et al. Periodontal Fibroblasts Modulate Proliferation and Osteogenic Differentiation of Embryonic Stem Cells Through Production of Fibroblast Growth Factors. JOURNAL OF PERIODONTOLOGY 85:645-654(2014).