Recombinant Human RUNX1T1, His-tagged

• Cat.No.: RUNX1T1-2472H
• Product Overview: Recombinant Human RUNX1T1 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-351aa
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) [ Homo sapiens ]
• Official Symbol: RUNX1T1
• Synonyms: RUNX1T1; runt-related transcription factor 1; translocated to, 1 (cyclin D-related); AML1T1, CBFA2T1, core binding factor, runt domain, alpha subunit 2; translocated to, 1; cyclin D related; protein CBFA2T1; CDR; ETO; MTG8; ZMYND2; eight twenty one protein; myeloid translocation gene on 8q22; zinc finger MYND domain-containing protein 2; acute myelogenous leukemia 1 translocation 1, cyclin-D related; core-binding factor, runt domain, alpha subunit 2; translocated to, 1; cyclin D-related; AML1T1; CBFA2T1; MGC2796; FLJ33145; DKFZp564B213
• Gene ID: 862
• mRNA Refseq: NM_175634
• Protein Refseq: NP_783552
• MIM: 133435
• UniProt ID: Q06455
• Chromosome Location: 8q22
• Pathway: Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; Pathways in cancer, organism-specific biosystem; Transcriptional misregulation in cancer, organism-specific biosystem; Transcriptional misregulation in cancer, conserved biosystem
• Function: DNA binding; identical protein binding; metal ion binding; protein binding; protein homodimerization activity; sequence-specific DNA binding transcription factor activity; zinc ion binding