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RXFP3

  • Official Full Name

    relaxin/insulin-like family peptide receptor 3

  • Overview

    Receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation.
  • Synonyms

    RXFP3; relaxin/insulin-like family peptide receptor 3; SALPR; RLN3R1; RXFPR3; GPCR135; relaxin-3 receptor 1; RLN3 receptor 1; relaxin 3 receptor 1; G-protein coupled receptor SALPR; g protein-coupled receptor SALPR; relaxin family peptide receptor 3; G-protein coupled receptor GPCR135; somatostatin and angiotensin-like peptide receptor; somatostatin- and angiotensin-like peptide receptor;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Assay Kits
  • Homo sapiens (Human)
  • Human
  • Mus musculus (Mouse)
  • Zebrafish
  • E.coli
  • E.coli expression system
  • Mammalian Cell
  • GST
  • His
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human RXFP3-2478H Recombinant Human RXFP3, GST-tagged E.coli GST 1-92aa
Human RXFP3-1553HCL Recombinant Human RXFP3 cell lysate N/A
Homo sapiens (Human) RFL21907HF Recombinant Full Length Human Relaxin-3 Receptor 1(Rxfp3) Protein, His-Tagged E.coli expression system His Full Length (1-469)
Mus musculus (Mouse) RFL6922MF Recombinant Full Length Mouse Relaxin-3 Receptor 1(Rxfp3) Protein, His-Tagged E.coli expression system His Full Length (1-472)
Zebrafish RXFP3-7042Z Recombinant Zebrafish RXFP3 Mammalian Cell His
Kit-1515 cAMP RXFP3 (SALPR) CHO-K1 GPCR Assay Kit N/A
Kit-1074 Diamine Oxidase Activity Assay Kit (Fluorometric) N/A
Kit-1516 RXFP3 CHO-K1 β-Arrestin GPCR Assay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • RXFP3 Related Articles
  • RXFP3 Related Research Area

RXFP3 involved in several pathways and played different roles in them. We selected most pathways RXFP3 participated on our site, such as Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with RXFP3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Neuroactive ligand-receptor interactionGABRA3;NMUR1;HRH4;HTR2CL1;P2RY1;F2RL1;GRIA2B;GABRG2;DRD2B

RXFP3 has several biochemical functions, for example, G-protein coupled peptide receptor activity, G-protein coupled receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RXFP3 itself. We selected most functions RXFP3 had, and list some proteins which have the same functions with RXFP3. You can find most of the proteins on our site.

Function Related Protein
G-protein coupled peptide receptor activityGRPR;MCHR2;GPR37L1;TSHR;RXFP4;CYSLTR1;NPR1;LTB4R2;GPR37
G-protein coupled receptor activityS1PR1;TAS2R114;SETD6;PTGER4B;ZFPM2B;EMR3;V2RH32;OR7C1;OR5H1

RXFP3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RXFP3 here. Most of them are supplied by our site. Hope this information will be useful for your research of RXFP3.

Liu, Y; Song, G; et al. Quantitative measurement of cell membrane receptor internalization by the nanoluciferase reporter: Using the G protein-coupled receptor RXFP3 as a model. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES 1848:688-694(2015).
Hosken, IT; Sutton, SW; et al. Relaxin-3 receptor (Rxfp3) gene knockout mice display reduced running wheel activity: Implications for role of relaxin-3/RXFP3 signalling in sustained arousal. BEHAVIOURAL BRAIN RESEARCH 278:167-175(2015).
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