S100A1 Protein


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Official Full Name S100 calcium binding protein A1
Background The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies.
Synonyms S100A1; S100 calcium binding protein A1; S100; S100A; S100-alpha; S100 calcium-binding protein A1; Protein S100-A1; S-100 protein subunit alpha; OTTHUMP00000035100; S-100 protein alpha chain; S100 alpha; S100 protein, alpha polypeptide
    • Species :
    • Cattle
    • Chicken
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293T
    • Human Cell
    • Mammalian Cell
    • Mammalian cells
    • Tag :
    • Fc
    • Flag
    • GST
    • His
    • MBP
    • S
    • His-SUMO
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human S100A1-200H Active Recombinant Human S100 calcium binding protein A1 E.coli N/A
    Human S100A1-3099H Recombinant Human S100A1, None tagged E.coli N/A
    Human S100A1-2480H Recombinant Human S100A1, GST-tagged E.coli GST
    Human S100A1-31005TH Recombinant Human S100A1 E.coli N/A
    Human S100A1-322H Recombinant Human S100A1 protein, His/MBP-tagged E.coli His/MBP
    Human S100A1-3718H Recombinant Human S100A1, His-tagged E.coli His
    Human S100A1-555H Recombinant Human S100A1 protein, His & S-tagged E.coli His/S
    Human S100A1-841H Recombinant Human S100A1, Fc tagged Human Cell Fc
    Mouse S100A1-14610M Recombinant Mouse S100A1 Protein Mammalian Cell His
    Mouse S100a1-3549M Recombinant Mouse S100 Calcium Binding Protein A1, His-tagged E.coli His
    Mouse S100a1-7012M Recombinant Mouse S100a1, His tagged E.coli His
    Rat S100A1-5210R Recombinant Rat S100A1 Protein Mammalian Cell His
    Rat S100a1-556R Recombinant Rat S100a1 protein, His-tagged E.coli His
    Chicken S100A1-5645C Recombinant Chicken S100A1 Mammalian Cell His
    Zebrafish S100A1-5506Z Recombinant Zebrafish S100A1 Mammalian Cell His
    Cattle S100A1-554C Recombinant Cattle S100A1 protein, His & GST-tagged E.coli His/GST
    Human S100A1-2861HCL Recombinant Human S100A1 cell lysate Human Cell N/A
    Human S100A1-3457H Recombinant Human S100A1 protein, His-SUMO-tagged E.coli His-SUMO
    Human S100A1-830HFL Recombinant Full Length Human S100A1 Protein, C-Flag-tagged Mammalian cells Flag
    Human S100A1-1909H Recombinant Human S100A1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human S100A1-318H Recombinant Human S100A1 protein, His-tagged E.coli His
    Mouse S100a1-5664M Recombinant Mouse S100a1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse S100a1-7317M Recombinant Mouse S100a1 Protein, His-tagged E.coli His

    S100A1 involved in several pathways and played different roles in them. We selected most pathways S100A1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with S100A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    S100A1 has several biochemical functions, for example, ATPase binding, S100 protein binding, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by S100A1 itself. We selected most functions S100A1 had, and list some proteins which have the same functions with S100A1. You can find most of the proteins on our site.

    Function Related Protein
    S100 protein binding S100A1; AGER; ANXA2; AHNAK; EZR; KCNK3; S100A11; FGF1A; ATP2A2; S100A6
    calcium ion binding DCHS1; EFHA2; NKD2; PCDH2G12; CBL; TBC1D8B; CANT1; PCDH12; S100A7A; EFCAB2
    calcium-dependent protein binding ANXA2; SEC31A; ANXA1; STX1A; PLSCR3; VPS37B; ANXA3; SNAP25; MYO1D; ANXA4
    identical protein binding RPE; SERPINA1A; ZNF212; TRIP13; CUBN; RAF1; VWA2; CD74; UGP2; SEPHS1
    protein binding RPS27A; APOOL; ZNF274; SLAMF7; RANGAP1; BRE; ZG16; MGAT5B; PALB2; ETL4
    protein homodimerization activity PSMD7; ZBTB1; BAXB; SH3GLB1; IDE; SRGAP2; PTPRO; IZUMO3; TFAP2A; TAP1

    S100A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with S100A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of S100A1.

    S100B; S100P

    Diaz-Romero, J; Quintin, A; et al. S100A1 and S100B Expression Patterns Identify Differentiation Status of Human Articular Chondrocytes. JOURNAL OF CELLULAR PHYSIOLOGY 229:1106-1117(2014).
    Rohde, D; Schon, C; et al. S100A1 is released from ischemic cardiomyocytes and signals myocardial damage via Toll-like receptor 4. EMBO MOLECULAR MEDICINE 6:778-794(2014).

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