Species : |
Human |
Source : |
E.coli |
Tag : |
His&S |
Protein Length : |
Met1~Ser94 |
Description : |
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies. |
Form : |
Freeze-dried powder |
Molecular Mass : |
Predicted Molecular Mass: 16.3 kDa |
Endotoxin : |
<1.0EU per 1µg (determined by the LAL method) |
Purity : |
> 95% |
Characteristic : |
The isoelectric point is 4.8. |
Applications : |
SDS-PAGE; WB; ELISA; IP. |
Stability : |
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : |
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Storage buffer : |
PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl. |
Reconstitution : |
Reconstitute in sterile PBS, pH7.2-pH7.4 |