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Official Full Name sphingosine-1-phosphate receptor 3
Background This gene encodes a member of the EDG family of receptors, which are G protein-coupled receptors. This protein has been identified as a functional receptor for sphingosine 1-phosphate and likely contributes to the regulation of angiogenesis and vascular endothelial cell function. [provided by RefSeq, Jul 2008]
Synonyms S1PR3; sphingosine-1-phosphate receptor 3; EDG3; LPB3; S1P3; EDG-3; sphingosine 1-phosphate receptor 3; S1P receptor 3; S1P receptor EDG3; S1P receptor Edg-3; sphingosine 1-phosphate receptor Edg-3; endothelial differentiation G-protein coupled receptor 3; G protein-coupled receptor, endothelial differentiation gene-3; endothelial differentiation, sphingolipid G-protein-coupled receptor, 3;
    • Species :
    • Human
    • Mouse
    • Source :
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human S1PR3-2084HCL Recombinant Human S1PR3 293 Cell Lysate HEK293 N/A
    Human S1PR3-28463TH Recombinant Human S1PR3 Wheat Germ N/A
    Human S1PR3-4040H Recombinant Human S1PR3 Protein, GST-tagged Wheat Germ GST
    Mouse S1PR3-14630M Recombinant Mouse S1PR3 Protein Mammalian Cell His

    s1pr3 involved in several pathways and played different roles in them. We selected most pathways s1pr3 participated on our site, such as Class A/1 (Rhodopsin-like receptors), G alpha (i) signalling events, GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with s1pr3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Class A/1 (Rhodopsin-like receptors) CHRM5; PENKA; GPR17; NPFF; SSTR3; CCBP2; CXCL11.8; HCRT; QRFPR; CCR6
    G alpha (i) signalling events CCL27; CCR7; SOUL3; CCR3; PYYA; CCL35.1; FPR-RS3; LPAR1; OXGR1; TAS2R3
    GPCR downstream signaling SOUL3; NMUR1; CHRM1; GNA13B; PROKR1A; CCR7; PLEKHG2; PROK1; SCT; AKAP13
    GPCR ligand binding FPR-RS6; CHRM5; EDN3; AMCF-II; NMS; OPN5; GPR55A; PTH2; NMU; ADCYAP1B
    Lysosphingolipid and LPA receptors LPAR2B; LPAR5A; S1PR1; S1PR3; LPAR2A; S1PR5B
    Neuroactive ligand-receptor interaction GLRA3; DRD2A; P2RX3; AGTR2; GHR; THRB; NPFFR2; P2RX1; GRIA4A; SSTR5
    S1P3 pathway S1PR3
    Signal Transduction ABI1B; CRABP1B; SKILB; FMNL1; ALDH8A1; OXGR1A.1; EVL; IQGAP3; INSL5; UCHL5

    s1pr3 has several biochemical functions, for example, G-protein coupled receptor activity, integrin binding, lipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by s1pr3 itself. We selected most functions s1pr3 had, and list some proteins which have the same functions with s1pr3. You can find most of the proteins on our site.

    Function Related Protein
    G-protein coupled receptor activity GPR65; OR103-4; OLFR469; MLNR; LPAR5A; TACR3L; GPR75; OLFR50; OR10A5; FZD1
    integrin binding COL4A3; ADAM10; NIPAL1; THY1; LYN; ADAM22; Tcam1; ICAM2; PPAP2B; GFAP
    lipid binding PSAP; ACBD4; APOA4; ATP5G3; STARD8; FABP6; MAL; PCYT1A; S100A13; PACSIN3
    protein binding UBASH3A; PENK; RAB14; ISOC2; FAM46C; RGS1; CRHBP; ZNF550; PHB2; KLF2
    sphingosine-1-phosphate receptor activity SPHK2; S1PR5A; S1PR1; GPR6; S1PR3A; S1PR5B; S1PR3; SPHK1; S1PR4; S1PR2

    s1pr3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with s1pr3 here. Most of them are supplied by our site. Hope this information will be useful for your research of s1pr3.


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