S1PR3

  • Official Full Name

    sphingosine-1-phosphate receptor 3

  • Overview

    This gene encodes a member of the EDG family of receptors, which are G protein-coupled receptors. This protein has been identified as a functional receptor for sphingosine 1-phosphate and likely contributes to the regulation of angiogenesis and vascular endothelial cell function. [provided by RefSeq, Jul 2008]
  • Synonyms

    S1PR3; sphingosine-1-phosphate receptor 3; EDG3; LPB3; S1P3; EDG-3; sphingosine 1-phosphate receptor 3; S1P receptor 3; S1P receptor EDG3; S1P receptor Edg-3; sphingosine 1-phosphate receptor Edg-3; endothelial differentiation G-protein coupled receptor 3; G protein-coupled receptor, endothelial differentiation gene-3; endothelial differentiation, sphingolipid G-protein-coupled receptor, 3;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)
  • E.coli expression system
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Flag
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human S1PR3-28463TH Recombinant Human S1PR3 Wheat Germ N/A 77 amino acids
Human S1PR3-4040H Recombinant Human S1PR3 Protein, GST-tagged Wheat Germ GST
Human S1PR3-2084HCL Recombinant Human S1PR3 293 Cell Lysate HEK293 N/A
Human S1PR3-4726HF Recombinant Full Length Human S1PR3 Protein, GST-tagged In Vitro Cell Free System GST 378 amino acids
Human S1PR3-1119HFL Recombinant Human S1PR3 protein, His&Flag-tagged HEK293 His&Flag 1-378 aa
Mouse S1PR3-14630M Recombinant Mouse S1PR3 Protein Mammalian Cell His
Mouse S1PR3-7873M Recombinant Mouse S1PR3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse S1PR3-7873M-B Recombinant Mouse S1PR3 Protein Pre-coupled Magnetic Beads HEK293
Homo sapiens (Human) RFL8305HF Recombinant Full Length Human Sphingosine 1-Phosphate Receptor 3(S1Pr3) Protein, His-Tagged E.coli expression system His Full Length (1-378)
Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) RFL27572TF Recombinant Full Length Takifugu Rubripes Sphingosine 1-Phosphate Receptor 3(S1Pr3) Protein, His-Tagged E.coli expression system His Full Length (1-384)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • S1PR3 Related Gene Family
  • S1PR3 Related Research Area

S1PR3 involved in several pathways and played different roles in them. We selected most pathways S1PR3 participated on our site, such as Class A/1 (Rhodopsin-like receptors), G alpha (i) signalling events, GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with S1PR3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Class A/1 (Rhodopsin-like receptors)SST;PROK2;CCR6;TAAR1;CNR1;ANXA1;RXFP2;FPR-RS6;ADRA2C
G alpha (i) signalling eventsCCR7;ADRA2A;OPN1LW;PPY;OXER1;RGS11;INSL5;RGS6;OPN5
GPCR downstream signalingRGS14;SST;PPY;CNR1;RGS12;RHOL;NMBB;HRH3;TAC1
GPCR ligand bindingGPR37L1;PROKR1;FPR-RS4;GPR65;ADORA2B;PTHLH;AGT;HEBP1;PYYA
Lysosphingolipid and LPA receptorsLPAR2A;LPAR5A;S1PR5B;S1PR3;S1PR1;LPAR2B
Neuroactive ligand-receptor interactionTRPV1;GRIA4A;GRIA4B;ADORA3;ADRA1BB;AGTR1B;VIPR1B;MC5RB;TAAR7F
S1P3 pathway
Signal TransductionUSP15;PRKCHB;EMR1;NCKIPSD;GPR77;S1PR5B;PROK1;NMS;PRICKLE1B

S1PR3 has several biochemical functions, for example, G-protein coupled receptor activity, integrin binding, lipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by S1PR3 itself. We selected most functions S1PR3 had, and list some proteins which have the same functions with S1PR3. You can find most of the proteins on our site.

Function Related Protein
G-protein coupled receptor activityCASR;Fzd4;CHRM2A;TAS2R121;GPR183B;GPR31;PTGER2B;GPR148;TAS2R136
integrin bindingDST;THBS4;PPAP2B;CD9;CTGFA;COL4A3;CD151;WISP2;LAMB2
lipid bindingBPIFB4;OSBPL11;APOL3;ACOT12;ESYT3;DBIL5;CRABP1B;APOA1B;CRABP2B
protein bindingATP6V1B2;CEBPG;ZWINT;CACNB4;MRC2;PAX9;CDA;FAM19A4;EFS
sphingosine-1-phosphate receptor activityS1PR5A;GPR6;S1PR1;S1PR3;S1PR4;S1PR5;SPHK2;S1PR2;S1PR3A

S1PR3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with S1PR3 here. Most of them are supplied by our site. Hope this information will be useful for your research of S1PR3.

ITGB4

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