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SCGB3A2

  • Official Full Name

    secretoglobin, family 3A, member 2

  • Overview

    The protein encoded by this gene is a secreted lung surfactant protein and a downstream target of thyroid transcription factor. A single nucleotide polymorphism in the promoter of this gene results in susceptibility to asthma.
  • Synonyms

    SCGB3A2; secretoglobin, family 3A, member 2; secretoglobin family 3A member 2; LU103; pneumo secretory protein 1; PNSP1; UGRP1; uteroglobin related protein 1; PnSP-1; Uteroglobin-related protein 1; OTTHUMP00000160144;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • E.coli
  • HEK293
  • Mammalian Cell
  • Yeast
  • His
  • HIS
  • His (Fc)
  • Avi
  • His|GST
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SCGB3A2-160H Recombinant Human SCGB3A2 Protein, HIS-tagged E.coli HIS
Human SCGB3A2-7649H Recombinant Human SCGB3A2 E.coli N/A
Mouse SCGB3A2-14745M Recombinant Mouse SCGB3A2 Protein Mammalian Cell His
Mouse SCGB3A2-7932M Recombinant Mouse SCGB3A2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse SCGB3A2-1926M Recombinant Mouse SCGB3A2 Protein (22-139 aa), His-tagged Yeast His 22-139 aa
Mouse SCGB3A2-7932M-B Recombinant Mouse SCGB3A2 Protein Pre-coupled Magnetic Beads HEK293
Mouse SCGB3A2-2175M Recombinant Mouse SCGB3A2 Protein (22-139 aa), His-GST-tagged E.coli His/GST 22-139 aa
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SCGB3A2 Related Articles
  • SCGB3A2 Related Research Area

SCGB3A2 involved in several pathways and played different roles in them. We selected most pathways SCGB3A2 participated on our site, such as Binding and Uptake of Ligands by Scavenger Receptors, Scavenging by Class A Receptors, Vesicle-mediated transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with SCGB3A2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Binding and Uptake of Ligands by Scavenger ReceptorsNFX1;AMBP;COL3A1;Alb;SPARC;IGKC;HPX;COL1A2;CD163
Scavenging by Class A Receptors
Vesicle-mediated transportGJA5;TERFA;STAB2;PPP6C;MIA3;TRAPPC6A;NAPG;TBC1D8B;SNX9

SCGB3A2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by SCGB3A2 itself. We selected most functions SCGB3A2 had, and list some proteins which have the same functions with SCGB3A2. You can find most of the proteins on our site.

Function Related Protein

SCGB3A2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SCGB3A2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SCGB3A2.

Wang, XT; Tanino, Y; et al. Secretoglobin 3A2 Attenuates Lipopolysaccharide-Induced Inflammation Through Inhibition of ERK and JNK Pathways in Bronchial Epithelial Cells. INFLAMMATION 38:828-834(2015).
Khavinson, VK; Tendler, SM; et al. Peptide Regulation of Gene Expression and Protein Synthesis in Bronchial Epithelium. LUNG 192:781-791(2014).
  • Q&As
  • Reviews

Q&As (7)

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How does SCGB3A2 contribute to lung development and repair? 12/10/2022

It plays a role in lung development and repair, contributing to epithelial cell growth and regeneration.

What role does SCGB3A2 play in pulmonary diseases? 02/27/2022

SCGB3A2 is implicated in various pulmonary diseases, including asthma and chronic obstructive pulmonary disease (COPD).

What is the primary role of SCGB3A2 in respiratory function? 10/22/2020

SCGB3A2, a secretoglobin, is involved in maintaining respiratory tract lining fluid balance and defending against pathogens.

How does SCGB3A2 interact with other proteins in the lung? 07/28/2020

SCGB3A2 works with other lung proteins in cellular signaling and immune responses.

How do genetic variations in SCGB3A2 affect lung health? 06/27/2018

Genetic variations in SCGB3A2 can influence susceptibility to respiratory ailments and lung function.

What potential therapeutic applications arise from targeting SCGB3A2 in lung diseases? 05/24/2018

Targeting SCGB3A2 could offer new treatment strategies for chronic lung diseases.

What is the impact of altered SCGB3A2 activity on respiratory conditions? 06/05/2017

Altered SCGB3A2 activity affects lung defense mechanisms, potentially exacerbating respiratory diseases.

Customer Reviews (3)

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Reviews
12/27/2020

    Swift and accurate. Critical for our experiments.

    11/09/2019

      Integral to our research success. Highly recommended.

      03/14/2017

        Invaluable service. Boosts research productivity.

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