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Official Full Name SUMO1/sentrin specific peptidase 7
Background The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see;SUMO1; MIM 601912) is required for many cellular processes. SUMO-specific proteases, such as SENP7, process SUMO;precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also display;isopeptidase activity for deconjugation of SUMO-conjugated substrates (Lima and Reverter, 2008 (PubMed;18799455)).
Synonyms SENP7; SUMO1/sentrin specific peptidase 7; SUMO1/sentrin specific protease 7; sentrin-specific protease 7; SUMO-1-specific protease 2; sentrin/SUMO-specific protease SENP7; KIAA1707; MGC157730
    • Species :
    • Human
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human SENP7-1971HCL Recombinant Human SENP7 293 Cell Lysate HEK293 N/A
    Human SENP7-1972HCL Recombinant Human SENP7 293 Cell Lysate HEK293 N/A
    Human SENP7-405H Recombinant Human SENP7 Protein, His-tagged E.coli His
    Human SENP7-7915H Recombinant Human SENP7 E.coli N/A
    Rat SENP7-5318R Recombinant Rat SENP7 Protein Mammalian Cell His

    SENP7 involved in several pathways and played different roles in them. We selected most pathways SENP7 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SENP7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    SENP7 has several biochemical functions, for example, cysteine-type peptidase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SENP7 itself. We selected most functions SENP7 had, and list some proteins which have the same functions with SENP7. You can find most of the proteins on our site.

    Function Related Protein
    cysteine-type peptidase activity CTSB; CLCA3; CAPN3; CTSSB.1; CTSBB; USP17L1P; CAPN3A; PSD; USP2A; SENP3A
    protein binding RNPS1; CPT1C; RARS; F2RL1; HIST1H3F; LPAR1; TCEB1; FBXO7; TLR1; CARTPT

    SENP7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SENP7 here. Most of them are supplied by our site. Hope this information will be useful for your research of SENP7.

    CBX5; TRIM28; BCL6

    Romeo, K; Louault, Y; et al. The SENP7 SUMO-Protease Presents a Module of Two HP1 Interaction Motifs that Locks HP1 Protein at Pericentric Heterochromatin. CELL REPORTS 10:771-782(2015).
    Alegre, KO; Reverter, D; et al. Structural insights into the SENP6 Loop1 structure in complex with SUMO2. PROTEIN SCIENCE 23:433-441(2014).

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