Recombinant Human SENP7 Protein, His-tagged

• Cat.No.: SENP7-405H
• Product Overview: Recombinant Human SENP7(Met630-Asp799) , transcript variant 2, fused with His tag at N-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 630-799 a.a.
• Description: The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for many cellular processes. SUMO-specific proteases, such as SENP7, process SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also display isopeptidase activity for deconjugation of SUMO-conjugated substrates (Lima and Reverter, 2008 [PubMed 18799455]).
• Form: 20mM HEPES, 5% Glycerol, pH 7.4. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
• Molecular Mass: 27.3 kDa
• Endotoxin: < 0.1 EU per µg protein as determined by LAL test
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: SENP7 SUMO1/sentrin specific peptidase 7 [ Homo sapiens ]
• Official Symbol: SENP7
• Synonyms: SENP7; SUMO1/sentrin specific peptidase 7; SUMO1/sentrin specific protease 7; sentrin-specific protease 7; SUMO-1-specific protease 2; sentrin/SUMO-specific protease SENP7; KIAA1707; MGC157730
• Gene ID: 57337
• mRNA Refseq: NM_001077203
• Protein Refseq: NP_001070671
• MIM: 612846
• UniProt ID: Q9BQF6