Serpind1
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Official Full Name
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
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Overview
The product encoded by this gene is a serine proteinase inhibitor which rapidly inhibits thrombin in the presence of dermatan sulfate or heparin. The gene contains five exons and four introns. This protein shares homology with antithrombin III and other members of the alpha 1-antitrypsin superfamily. Mutations in this gene are associated with heparin cofactor II deficiency. -
Synonyms
SERPIND1; serpin peptidase inhibitor, clade D (heparin cofactor), member 1; HCF2, serine (or cysteine) proteinase inhibitor, clade D (heparin cofactor), member 1; heparin cofactor 2; D22S673; HC II; HC2; heparin cofactor II; HLS2; serpin D1; leuserpin 2;
- Recombinant Proteins
- Cell & Tissue Lysates
- Antibody
- Native Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
- Human Cell
- Human plasma
- Mammalian Cell
- Mammalian cells
- Mouse
- C
- His
- GST
- His (Fc)
- Avi
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- Serpind1 Related Articles
- Serpind1 Related Research Area
Serpind1 involved in several pathways and played different roles in them. We selected most pathways Serpind1 participated on our site, such as Complement and coagulation cascades, which may be useful for your reference. Also, other proteins which involved in the same pathway with Serpind1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Complement and coagulation cascades | CD46;MBL2;F9;CFD;VWF;C1R;SERPINF2;C1QB;PLAU |
Serpind1 has several biochemical functions, for example, endopeptidase inhibitor activity, heparin binding, serine-type endopeptidase inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Serpind1 itself. We selected most functions Serpind1 had, and list some proteins which have the same functions with Serpind1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| endopeptidase inhibitor activity | A1i3;SPINK1;C4A;C3A.6;SLPI;SERPINA1A;PZP;Serpina1b;MUG1 |
| heparin binding | ZNF146;CCL15;PTPRFB;NRP1A;BSPH1;VEGFA;APPA;APP;TGFBR3 |
| serine-type endopeptidase inhibitor activity | PTI;APP;SERPINH2;SPINK7;SERPINB7;SERPINE2;AGT;ITIH5;SERPINE3 |
Serpind1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Serpind1 here. Most of them are supplied by our site. Hope this information will be useful for your research of Serpind1.
p29991-pro_0000037940; p29991-pro_0000037946; p29991-pro_0000308465; q99ib8-pro_0000045599; d-mannose; IGHG1; IGHA1; TF
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