Recombinant Human SLC40A1 Protein (T2-V571), 8×His-MBP, Flag tagged

• Cat.No.: SLC40A1-0628H
• Product Overview: Recombinant Human 8His-MBP-TEV-(GG)-SLC40A1(T2-V571 end)-Flag Protein was expressed in Insect cell.

Specification

• Description: Major iron transporter that plays a key role in balancing cellular and systemic iron levels. Transports iron from intestinal, splenic, and hepatic cells into the blood to provide iron to other tissues. Controls therefore dietary iron uptake, iron recycling by macrophages, and release of iron stores in hepatocytes. When iron is in excess, hepcidin/HAMP levels increase resulting in a degradation of ferroportin/SLC40A1 limiting the iron efflux to plasma.
• Source: Insect cell
• Species: Human
• Tag: 8His-MBP,Flag
• Form: Liquid
• Protein Length: T2-V571
• Endotoxin: < 0.01 EU per μg of the protein
• Purity: 90%
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Formulation:
• Shipping: It is shipped out with blue ice.

Gene Information

• Gene Name: SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1 [ Homo sapiens (human) ]
• Official Symbol: SLC40A1
• Synonyms: SLC40A1; solute carrier family 40 (iron-regulated transporter), member 1; SLC11A3, solute carrier family 11 (proton coupled divalent metal ion transporters), member 3; solute carrier family 40 member 1; ferroportin 1; FPN1; HFE4; IREG1; MTP1; ferroportin-1; iron regulated gene 1; iron-regulated transporter 1; putative ferroportin 1 variant IIIB; solute carrier family 11 (proton-coupled divalent metal ion transporters), member 3; MST079; MSTP079; SLC11A3
• Gene ID: 30061
• mRNA Refseq: NM_014585
• Protein Refseq: NP_055400
• MIM: 604653
• UniProt ID: Q9NP59