SNTA1

  • Official Full Name

    syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)

  • Overview

    Dystrophin is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The protein encoded by this gene is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally-related genes.

  • Synonyms

    SNTA1;syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component);SNT1, syntrophin, alpha 1 (dystrophin associated protein A1, 59kD, acidic component);alpha-1-syntrophin;pro TGF alpha cytoplasmic domain interacting protein 1;TACIP1;59 kDa dystrophin associated protein A1 acidic component 1;59 kDa dystrophin-associated protein A1 acidic component 1;Acidic alpha 1 syntrophin;Alpha 1 syntrophin;dJ1187J4.5;Dystrophin associated protein A159kD acidic component;Dystrophin associated protein A1 59kDa acidic component;LQT12;OTTHUMP00000030650;Pro-TGF-alpha cytoplasmic domain-interacting protein 1;SNT 1;SNT1;SNTA 1;SNTA1_HUMAN;Syntrophin 1;Syntrophin alpha dystrophin associated protein A1 59kD acidic component;Syntrophin-1;Syntrophin1;TACIP 1

Recombinant Proteins

  • Human
  • Rhesus macaque
  • Mouse
  • E.coli
  • Mammalian Cells
  • HEK293
  • His
  • Non
  • Avi
  • Fc
  • DDK
  • Myc

    Involved Pathway

    SNTA1 involved in several pathways and played different roles in them. We selected most pathways SNTA1 participated on our site, such as SIDS Susceptibility Pathways,Signaling mediated by p38-gamma and p38-delta, which may be useful for your reference. Also, other proteins which involved in the same pathway with SNTA1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    SIDS Susceptibility Pathways PHOX2B,FOXM1,ECE1,DLX2,SCN3B,CTCF,PLP1,RUNX3,KCNH2,POU3F2

    Protein Function

    SNTA1 has several biochemical functions, for example, ATPase binding,PDZ domain binding,actin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SNTA1 itself. We selected most functions SNTA1 had, and list some proteins which have the same functions with SNTA1. You can find most of the proteins on our site.

    Function Related Protein
    ATPase binding ATP6V0A2B,DNAJB1,SELS,DNAJC10,ATP6V1E1,SLN,SNX10,PKD2,TCIRG1,NSFL1C
    structural molecule activity CTNNA1,INAA,KRT3,COPE,FLG2,CLDN20,KRT222,KRT80,MAP1B,MPZL1
    actin binding NF2B,CCDC88A,GAS2L3,TRPV4,MSRB1,WASLB,DIAPH1,HIP1RB,KLHL20,SNTG1
    protein binding SMAD4,PLK1,NPLOC4,C9orf100,PPP2R5A,PICALM,VIM,PPP1R1A,IL15RA,ABCG1
    contributes_to sodium channel regulator activity ATP2B4
    nitric-oxide synthase binding SLC6A4,CD74,CAMK2D,CDH2,CAV3,CALM1,CALM3,DNM2,DNM3,SLC14A2
    calmodulin binding ITPKC,UPF3B,EDF1,PPP3CC,MYH1B,MARCKSL1B,KCNN4,TRPV1,MYO9B,PHKG1B
    PDZ domain binding LPAR1,DLC,F11R,GNG5,ADRB1,ARHGEF16,ATP2B1A,Fzd4,ATP2B4,CRIPT
    ion channel binding PRKCSH,CALM1,KCNB2,KCNQ3,TRPC1,CAMK2D,KCNE2,ACTN4,ACTN2,CAV1

    Interacting Protein

    SNTA1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SNTA1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SNTA1.

    Mapk12;ABCA1;TFAP2A;XRCC6;Sstr2;UBE2V2;MED8

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