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SNX10

Official Full Name

sorting nexin 10
Overview

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a;phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled;coil region, like some family members. This gene may play a role in regulating endosome homeostasis. Alternative;splicing results in multiple transcript variants.
Synonyms

SNX10; sorting nexin 10; sorting nexin-10; 2410004M09Rik; MGC109202; MGC33054; SNX10_HUMAN; OTTHUMP00000122521; OTTHUMP00000122522; OTTHUMP00000202476; OTTHUMP00000202479;

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Rhesus Macaque

Source

E.coli
HEK293
HEK293T
Mammalian Cell

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	SNX10-1604HCL	Recombinant Human SNX10 293 Cell Lysate	HEK293	Non		Inquiry
Human	SNX10-3892H	Recombinant Human SNX10 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc&DDK		Inquiry
Human	SNX10-301313H	Recombinant Human SNX10 protein, GST-tagged	E.coli	GST	His124-Ser201	Inquiry
Mouse	Snx10-6020M	Recombinant Mouse Snx10 Protein, Myc/DDK-tagged	HEK293T	Myc&DDK		Inquiry
Rhesus Macaque	SNX10-4387R	Recombinant Rhesus monkey SNX10 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	SNX10-4203R	Recombinant Rhesus Macaque SNX10 Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi		Inquiry
Rhesus Macaque	SNX10-4203R-B	Recombinant Rhesus Macaque SNX10 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Chicken	SNX10-2670C	Recombinant Chicken SNX10	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

SNX10 involved in several pathways and played different roles in them. We selected most pathways SNX10 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SNX10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

SNX10 has several biochemical functions, for example, 1-phosphatidylinositol binding, ATPase binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SNX10 itself. We selected most functions SNX10 had, and list some proteins which have the same functions with SNX10. You can find most of the proteins on our site.

Function	Related Protein
1-phosphatidylinositol binding	ZFYVE9;MCF2L;PICALM;WDFY3;SCIN;SNAP91;EEA1;PICALMB;SCARB1
ATPase binding	ZNHIT6;SNTA1;METTL21A;SYVN1;FXYD7;ATP6V1G1;LCK;ATP6V0A1B;ATP6V0A2
protein binding	DRG2;HIST1H4I;LCA5;FZD2;UBXN6;SLC4A4;USP34;GRIN3A;TRAPPC5

SNX10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SNX10 here. Most of them are supplied by our site. Hope this information will be useful for your research of SNX10.

ARL6IP1

Research Area

Xu, TT; Xu, JX; et al. Structure of human SNX10 reveals insights into its role in human autosomal recessive osteopetrosis. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS 82:3483-3489(2014).

Sui, WG; He, HY; et al. ChIP-seq analysis of histone H3K9 trimethylation in peripheral blood mononuclear cells of membranous nephropathy patients. BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH 47:42-49(2014).