SNX17
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Official Full Name
sorting nexin 17
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Overview
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but contains a B41 domain. This protein interacts with the cytoplasmic domain of P-selectin, and may function in the intracellular trafficking of P-selectin. -
Synonyms
SNX17; sorting nexin 17; sorting nexin-17; KIAA0064; Similar to a putative C elegans gene encoded in cosmid F17H10;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
- HEK293T
- Mammalian Cell
- GST
- His
- Fc
- Avi
- Myc
- DDK
- Non
- Involved Pathway
- Protein Function
- Interacting Protein
SNX17 involved in several pathways and played different roles in them. We selected most pathways SNX17 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SNX17 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
SNX17 has several biochemical functions, for example, low-density lipoprotein particle receptor binding, phosphatidylinositol binding, protein C-terminus binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SNX17 itself. We selected most functions SNX17 had, and list some proteins which have the same functions with SNX17. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| low-density lipoprotein particle receptor binding | LDLRAP1;SACS;APOEB;APOEA;APOE;LRPAP1;ARRB2;PCSK9;SYT1 |
| phosphatidylinositol binding | SNX27A;SNX33;SH3PXD2A;NCF1;TUB;SNX18B;SNX2;SNX10A;NOXO1 |
| protein C-terminus binding | HSPB7;TERF2;MAP2K1;NCF2;BLOC1S2A;SDC1;KPNA3;HIC2;AXIN1 |
| protein binding | PTCH1;C2orf62;TRIM35;ITGB1BP1;STK24;UBL4A;GTF2H1;PLEKHG6;CEP57L1 |
| receptor binding | GFRA1;FGF13B;CCL17;FGF12A;EDA;RAB8B;POU2F1;SEMA4D;NCK1 |
SNX17 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SNX17 here. Most of them are supplied by our site. Hope this information will be useful for your research of SNX17.
PLCG1; ABL1; FYN; SRC; NCK1; PIK3R1; CRK; GRB2; SKIL; RLIM; pi3p
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