Recombinant Mouse Snx17 Protein, Myc/DDK-tagged

Cat.No. : Snx17-6025M
Product Overview : Purified recombinant protein of mouse full-length sorting nexin 17 (Snx17), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
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Description : Critical regulator of endosomal recycling of numerous surface proteins, including integrins, signaling receptor and channels. Binds to NPxY sequences in the cytoplasmic tails of target cargos. Associates with retriever and CCC complexes to prevent lysosomal degradation and promote cell surface recycling of numerous cargos such as integrins ITGB1, ITGB5 and their associated alpha subunits. Also required for maintenance of normal cell surface levels of APP and LRP1. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)).
Source : HEK293T
Species : Mouse
Tag : Myc/DDK
Molecular Mass : 52.8 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Snx17 sorting nexin 17 [ Mus musculus (house mouse) ]
Official Symbol : Snx17
Synonyms : SNX17; sorting nexin 17; sorting nexin-17; AI790646; mKIAA0064; D5Ertd260e; 5830447M19Rik
Gene ID : 266781
mRNA Refseq : NM_153680
Protein Refseq : NP_710147
UniProt ID : Q8BVL3

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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