SNX3 Protein

SNX3

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SNX3

Official Full Name sorting nexin 3
Background This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like most family members. This protein interacts with phosphatidylinositol-3-phosphate, and is involved in protein trafficking.
Synonyms SNX3; sorting nexin 3; sorting nexin-3; Grd19; MCOPS8; MGC151262; MGC151266; MGC17570; OTTHUMP00000016941; OTTHUMP00000046475; OTTHUMP00000046476; Protein SDP3; SDP3; SNX3_HUMAN; SNX3A; Sorting nexin 3A
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human SNX3-31428TH Recombinant Human SNX3, His-tagged E.coli His
    Rat SNX3-5659R Recombinant Rat SNX3 Protein Mammalian Cell His
    Rhesus Macaque SNX3-4397R Recombinant Rhesus monkey SNX3 Protein, His-tagged Mammalian Cell His
    Chicken SNX3-1550C Recombinant Chicken SNX3 Mammalian Cell His
    Zebrafish SNX3-3477Z Recombinant Zebrafish SNX3 Mammalian Cell His
    Human SNX3-3584H Recombinant Human SNX3, His-tagged E.coli His
    Human SNX3-1591HCL Recombinant Human SNX3 293 Cell Lysate HEK293 N/A
    Human SNX3-5161H Recombinant Human SNX3 protein, GST-tagged E.coli GST
    Human SNX3-4882H Recombinant Human SNX3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Snx3-6031M Recombinant Mouse Snx3 Protein, Myc/DDK-tagged HEK293T Myc/DDK

    SNX3 involved in several pathways and played different roles in them. We selected most pathways SNX3 participated on our site, such as Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with SNX3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Endocytosis TGFBR1; STRUMPELLIN; RAB8A; FAM125A; AGAP1; ARR3B; PLD1A; RAB35; SMAP2; CYTH3

    SNX3 has several biochemical functions, for example, phosphatidylinositol-3,5-bisphosphate binding, phosphatidylinositol-3-phosphate binding, phosphatidylinositol-4-phosphate binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SNX3 itself. We selected most functions SNX3 had, and list some proteins which have the same functions with SNX3. You can find most of the proteins on our site.

    Function Related Protein
    phosphatidylinositol-3,5-bisphosphate binding WDR45B; GBF1; SNX14; WDR45; WDR45L; RAG2; D6WSU116E; CLVS1; KIF16B; MAPKAP1
    phosphatidylinositol-3-phosphate binding SNX21; ZFYVE28; JPH2; PLEKHF1; SNX20; WIPI2; WDR45; SNX27; D6WSU116E; LANCL2
    phosphatidylinositol-4-phosphate binding OSBP; ARFIP1; PLEKHA8; CLSTN2; D6WSU116E; PRRC2B; OSBPL5; SESTD1; PLEKHF1; SH3PXD2B
    phosphatidylinositol-5-phosphate binding D6WSU116E; SH3PXD2B; LANCL2; SESTD1; FAM21C; JPH2; RS1; SNX3; PLEKHF1; WIPI2
    protein binding SOCS4; TCP1; C16orf48; C12orf40; FAM125A; SIRT2; HIST1H3F; KDRL; L3MBTL1; NIP7
    protein phosphatase binding IRS2; MAP2K7; HSF4; CDC27; DRD1; MAPK14; PPP6R3; TRAF3; LCK; PIK3R2

    SNX3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SNX3 here. Most of them are supplied by our site. Hope this information will be useful for your research of SNX3.

    ARL6IP1; ABL1; FYN; EPB41; SRC; NCK1; MCC; HLA-B; VHL; CRK; GRB2; IKBKE; ATG5; STX11; PDE4DIP; pi3p

    Tai, GH; Lu, L; et al. Participation of the syntaxin 5/Ykt6/GS28/GS15 SNARE complex in transport from the early/recycling endosome to the trans-Golgi network. MOLECULAR BIOLOGY OF THE CELL 15:4011-4022(2004).
    Xu, Y; Hortsman, H; et al. SNX3 regulates endosomal function through its PX-domain-mediated interaction with Ptdlns(3)P. NATURE CELL BIOLOGY 3:658-666(2001).

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