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SNX3

  • Official Full Name

    sorting nexin 3

  • Overview

    This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like most family members. This protein interacts with phosphatidylinositol-3-phosphate, and is involved in protein trafficking.
  • Synonyms

    SNX3; sorting nexin 3; sorting nexin-3; Grd19; MCOPS8; MGC151262; MGC151266; MGC17570; OTTHUMP00000016941; OTTHUMP00000046475; OTTHUMP00000046476; Protein SDP3; SDP3; SNX3_HUMAN; SNX3A; Sorting nexin 3A;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SNX3-3584H Recombinant Human SNX3, His-tagged E.coli His
Human SNX3-31428TH Recombinant Human SNX3, His-tagged E.coli His 162 amino acids
Human SNX3-1591HCL Recombinant Human SNX3 293 Cell Lysate HEK293 N/A
Human SNX3-5161H Recombinant Human SNX3 protein, GST-tagged E.coli GST 3-162aa
Human SNX3-4882H Recombinant Human SNX3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse Snx3-6031M Recombinant Mouse Snx3 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat SNX3-5659R Recombinant Rat SNX3 Protein Mammalian Cell His
Rat SNX3-5318R Recombinant Rat SNX3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat SNX3-5318R-B Recombinant Rat SNX3 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque SNX3-4397R Recombinant Rhesus monkey SNX3 Protein, His-tagged Mammalian Cell His
Rhesus Macaque SNX3-4213R Recombinant Rhesus Macaque SNX3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque SNX3-4213R-B Recombinant Rhesus Macaque SNX3 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish SNX3-3477Z Recombinant Zebrafish SNX3 Mammalian Cell His
Chicken SNX3-1550C Recombinant Chicken SNX3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

SNX3 involved in several pathways and played different roles in them. We selected most pathways SNX3 participated on our site, such as Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with SNX3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
EndocytosisRABEP1;FAM21C;GRK7A;ARPC5LB;RAB35;MVB12A;HLA-B;SH3GLB1A;GIT1

SNX3 has several biochemical functions, for example, phosphatidylinositol-3,5-bisphosphate binding, phosphatidylinositol-3-phosphate binding, phosphatidylinositol-4-phosphate binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SNX3 itself. We selected most functions SNX3 had, and list some proteins which have the same functions with SNX3. You can find most of the proteins on our site.

Function Related Protein
phosphatidylinositol-3,5-bisphosphate bindingRS1;D6WSU116E;WDR45L;GBF1;CLVS2;FAM21C;SNX3;WDR45;CLVS1
phosphatidylinositol-3-phosphate bindingWDR45;VPS36;SNX27;WIPI1;D6WSU116E;NCF4;ZFYVE26;SNX19;WDR45B
phosphatidylinositol-4-phosphate bindingLANCL2;D6WSU116E;JPH2;COL4A3BP;OSBPL8;ARFIP2;MBL1;SNX24;PLEKHF1
phosphatidylinositol-5-phosphate bindingD6WSU116E;LANCL2;PLEKHF1;SNX24;FAM21C;SNX3;PHLDA3;RS1;SH3PXD2B
protein bindingARMC9;PARL;PDPK1;RAPGEF3;NPHP1;POP5;LAMTOR3;SCGB2A2;MTMR14
protein phosphatase bindingJUP;MVP;ROS1;PPP6R1;SHOC2;DRD1;DLG3;CSK;TRAF2

SNX3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SNX3 here. Most of them are supplied by our site. Hope this information will be useful for your research of SNX3.

ARL6IP1; ABL1; FYN; EPB41; SRC; NCK1; MCC; HLA-B; VHL; CRK; GRB2; IKBKE; ATG5; STX11; PDE4DIP; pi3p

Research Area

Related articles

Tai, GH; Lu, L; et al. Participation of the syntaxin 5/Ykt6/GS28/GS15 SNARE complex in transport from the early/recycling endosome to the trans-Golgi network. MOLECULAR BIOLOGY OF THE CELL 15:4011-4022(2004).
Xu, Y; Hortsman, H; et al. SNX3 regulates endosomal function through its PX-domain-mediated interaction with Ptdlns(3)P. NATURE CELL BIOLOGY 3:658-666(2001).
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