Recombinant Human SNX3, His-tagged

• Cat.No.: SNX3-3584H
• Product Overview: Recombinant human SNX3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques (1-162 aa).

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: Sorting nexin 3(SNX3), also known as SDP3, is a member of the large family of hydrophilic proteins that interact with a variety of receptor types and are involved in intracellular trafficking. This protein interacts with phosphatidylinositol-3-phosphate, and is involved in protein trafficking. SNX3 comprises a distinct subgroup of nexins that share less sequence similarity outside of the PX domain and have dramatically different binding affinities for the tyrosine kinase receptors.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol, 0.1M NaCl
• Molecular Weight: 20.9 kDa (182aa), confirmed by MALDI-TOF
• Purity: > 95% by SDS - PAGE
• Concentration: 1 mg/ml (determined by Bradford assay)
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MAETVADTRR LITKPQNLND AYGPPSNFLE IDVSNPQTVG VGRGRFTTYE IRVKTNLPIF KLKESTVRRR YSDFEWLRSE LERESKVVVP PLPGKAFLRQ LPFRGDDGIF DDNFIEERKQ GLEQFINKVA GHPLAQNERC LHMFLQDEII DKSYTPSKIR HA
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: SNX3 sorting nexin 3 [ Homo sapiens ]
• Official Symbol: SNX3
• Synonyms: SNX3; SDP3; Grd19; MCOPS8; MGC17570; sorting nexin 3; sorting nexin-3; sorting nexin 3A; OTTHUMP00000016941; OTTHUMP00000046475; OTTHUMP00000046476
• Gene ID: 8724
• mRNA Refseq: NM_003795
• Protein Refseq: NP_003786
• MIM: 605930
• UniProt ID: O60493
• Chromosome Location: 6q21
• Function: lipid binding; phosphatidylinositol-3-phosphate binding; protein binding; protein phosphatase binding