SOX8
-
Official Full Name
SRY (sex determining region Y)-box 8
-
Overview
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome). -
Synonyms
SOX8; SRY (sex determining region Y)-box 8; transcription factor SOX-8; MGC24837; SOX 8; SRY (sex determining region Y) box 8; SRY box 8; SRY box containing gene 8; Transcription factor SOX 8; Transcription factor SOX8; OTTHUMP00000151195;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- E.coli
- HEK293
- HEK293T
- Mammalian Cell
- His
- Fc
- Avi
- Myc
- DDK
- Non
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | SOX8-2885H | Recombinant Human SOX8, His-tagged | E.coli | His | C-149aa | |
| Human | SOX8-1673M | Sol8 (mouse myoblast) whole cell lysate | Non |
|
||
| Human | SOX8-1743H | Recombinant Human SOX8 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Myc&DDK |
|
|
| Human | SOX8-2419H | Recombinant Human SOX8 Protein, MYC/DDK-tagged | HEK293 | Myc&DDK |
|
|
| Human | SOX8-2795H | Recombinant Human SOX8 protein(121-230 aa), C-His-tagged | E.coli | His | 121-230 aa |
|
| Mouse | SOX8-15787M | Recombinant Mouse SOX8 Protein | Mammalian Cell | His |
|
|
| Mouse | SOX8-8594M | Recombinant Mouse SOX8 Protein, His (Fc)-Avi-tagged | HEK293 | His&Fc&Avi |
|
|
| Mouse | Sox8-6059M | Recombinant Mouse Sox8 Protein, Myc/DDK-tagged | HEK293T | Myc&DDK |
|
|
| Mouse | SOX8-8594M-B | Recombinant Mouse SOX8 Protein Pre-coupled Magnetic Beads | HEK293 |
|
||
| Chicken | SOX8-6296C | Recombinant Chicken SOX8 | Mammalian Cell | His |
|
- Involved Pathway
- Protein Function
- Interacting Protein
SOX8 involved in several pathways and played different roles in them. We selected most pathways SOX8 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SOX8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
SOX8 has several biochemical functions, for example, DNA binding, RNA polymerase II core promoter sequence-specific DNA binding, RNA polymerase II transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SOX8 itself. We selected most functions SOX8 had, and list some proteins which have the same functions with SOX8. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | ZNF669;ARNTL2;CARHSP1;GZF1;ASCL4;LIG3;CMYB;MEIS2B;AHDC1 |
| RNA polymerase II core promoter sequence-specific DNA binding | SOX11;SMYD3;TFAP2A;ZFP335;TCF7L2;NR4A2;H3F3B;MAZ;RBPJ |
| RNA polymerase II transcription factor activity, sequence-specific DNA binding | JUNB;FOXQ1B;FOXL1;BHLHE40;HOXA13A;FLI1;ERG;FOXJ3;CC2D1A |
| protein heterodimerization activity | TENM2;CASP8;MTTP;TGFB2;TENM3;PPP3CB;DMRTA2;SOX14;ABCG1 |
| transcription factor binding | CREBBP;KAT2A;NCOR2;HTT;DIP2B;TRIB1;TMEM173;UBE2I;KAT8 |
SOX8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SOX8 here. Most of them are supplied by our site. Hope this information will be useful for your research of SOX8.
MMP1; JAM2; PIDD1; NOD1
- Reviews
- Q&As
Ask a Question for All SOX8 Products
Required fields are marked with *
My Review for All SOX8 Products
Required fields are marked with *
