Description : |
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the cognitive disability found in an alpha-thalassemia-related syndrome (ART-16). This protein is also highly expressed in the majority of human hepatocellular carcinomas and promotes cellular proliferation and enhanced tumor growth. |
Source : |
HEK293 |
Species : |
Human |
Tag : |
Myc/DDK |
Molecular Mass : |
47.3 kDa |
AA Sequence : |
MLDMSEARSQPPCSPSGTASSMSHV EDSDSDAPPSPAGSEGLGRAGVAVG GARGDPAEAADERFPACIRDAVSQV LKGYDWSLVPMPVRGGGGGALKAKP HVKRPMNAFMVWAQAARRKLADQYP HLHNAELSKTLGKLWRLLSESEKRP FVEEAERLRVQHKKDHPDYKYQPRR RKSAKAGHSDSDSGAELGPHPGGGA VYKAEAGLGDGHHHGDHTGQTHGPP TPPTTPKTELQQAGAKPELKLEGRR PVDSGRQNIDFSNVDISELSSEVMG TMDAFDVHEFDQYLPLGGPAPPEPG QAYGGAYFHAGASPVWAHKSAPSAS ASPTETGPPRPHIKTEQPSPGHYGD QPRGSPDYGSCSGQSSATPAAPAGP FAGSQGDYGDLQASSYYGAYPGYAP GLYQYPCFHSPRRPYASPLLNGLAL PPAHSPTSHWDQPVYTTLTRPTRTR PLEQKLISEEDLAANDILDYKDDDD KV |
Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : |
50 μg/mL as determined by BCA |
Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |