SRP68
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Official Full Name
signal recognition particle 68kDa -
Overview
This gene encodes a subunit of the signal recognition particle (SRP). The SRP is a ribonucleoprotein complex that;transports secreted and membrane proteins to the endoplasmic reticulum for processing. The complex includes a 7S RNA;and six protein subunits. The encoded protein is the 68kDa component of the SRP, and forms a heterodimer with the;72kDa subunit that is required for SRP function. Alternatively spliced transcript variants encoding multiple isoforms;have been observed for this gene, and three pseudogenes of this gene are located within the Smith-Magenis syndrome;region on chromosome 17. -
Synonyms
SRP68;signal recognition particle 68kDa;signal recognition particle 68 kDa protein;Signal recognition particle 68 kDa;SRP 68;SRP68_HUMAN;68kDA subunit of signal recognition particle
Recombinant Proteins
- Chicken
- Zebrafish
- Mouse
- Human
- Mammalian Cells
- E.coli
- HEK293
- His
- SUMO
- MBP
- Avi
- Fc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SRP68-1353C | Recombinant Chicken SRP68 | Mammalian Cells | Chicken | His |
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| SRP68-1414Z | Recombinant Zebrafish SRP68 | Mammalian Cells | Zebrafish | His |
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| SRP68-15992M | Recombinant Mouse SRP68 Protein | Mammalian Cells | Mouse | His |
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| SRP68-01H | Recombinant Human SRP68 protein, His tagged | E.coli | Human | His |
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| SRP68-11H | Recombinant Human SRP68 protein, His-SUMO-tagged | E.coli | Human | His&SUMO | 11-580 aa |
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| SRP68-12H | Recombinant Human SRP68 protein, MBP&His-tagged | E.coli | Human | His&MBP | Gly11-Gly580 |
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| SRP68-8721M | Recombinant Mouse SRP68 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| SRP68-8721M-B | Recombinant Mouse SRP68 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
SRP68 involved in several pathways and played different roles in them. We selected most pathways SRP68 participated on our site, such as Protein export, which may be useful for your reference. Also, other proteins which involved in the same pathway with SRP68 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Protein export | IMMP2L,SEC61A1,SPCS2,SRP54B,SRP9,SRPRB,IMMP1L,SRP14,secB,SEC61G |
Protein Function
SRP68 has several biochemical functions, for example, 7S RNA binding,RNA binding,endoplasmic reticulum signal peptide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SRP68 itself. We selected most functions SRP68 had, and list some proteins which have the same functions with SRP68. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| poly(A) RNA binding | DDX24,CCDC108,RBM28,APOBEC3F,RPL23A,CDKN2A,HSPB1,MRPS35,MTPAP,GNL3L |
| signal recognition particle binding | SRP72,SRP9,SRPR |
| signal sequence binding | AP2M1,AP2B1 |
| 7S RNA binding | SRP14,SRP19,SRP9,SRP54,SRP72,EXOSC2,SRP54A,PIGC |
| endoplasmic reticulum signal peptide binding | SRP54A,SRP54B,PIGC,SRP14,SRP54 |
| RNA binding | NOVA1,DIS3,RCAN3,KHDRBS1B,BICC1,PATL1,RPL4,SURF6,NOL3,TARDBP |
Interacting Protein
SRP68 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SRP68 here. Most of them are supplied by our site. Hope this information will be useful for your research of SRP68.
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