Taar1
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Official Full Name
trace amine associated receptor 1 -
Overview
TAAR1 is a G protein-coupled receptor activated by trace amines. Trace amines are endogenous amine compounds that;account for less than 1% of the biogenic amines in most brain regions (Bunzow et al., 2001 (PubMed;11723224)). -
Synonyms
TAAR1;trace amine associated receptor 1;trace amine receptor 1 , TRAR1;trace amine-associated receptor 1;TA1;TAR1;taR-1;trace amine receptor 1;TRAR1;RP11-295F4.9;MGC126874;MGC138399
Recombinant Proteins
- Rat
- Mouse
- Rhesus macaque
- Human
- Mus musculus
- Macaca mulatta
- Pan troglodytes
- E.coli
- Mammalian Cells
- HEK293
- His
- SUMO
- Avi
- Fc
Involved Pathway
Taar1 involved in several pathways and played different roles in them. We selected most pathways Taar1 participated on our site, such as Amine ligand-binding receptors,Class A/1 (Rhodopsin-like receptors),G alpha (s) signalling events, which may be useful for your reference. Also, other proteins which involved in the same pathway with Taar1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| GPCR ligand binding | OXTRL,OXER1,CCR8,NMBB,OPN5,INSL5,ADM2A,EDN3,EDNRB,PRLH |
| G alpha (s) signalling events | PTH,ADM2A,RAMP2,RXFP2,PTHRP2,RAMP3,NPSR1,CRH,DRD5,RLN3 |
| Signaling by GPCR | GPR65,GPR37B,SST1.1,RCA2.1,OPN1SW1,TRH,OR52B4,RLN2,RXFP2B,FGD2 |
| GPCR downstream signaling | NMBB,OPN4A,GPR132,CCR1,OXGR1A.2,CHRM2,TRPC6A,NMB,KALRNB,RGS11 |
| Class A/1 (Rhodopsin-like receptors) | S1PR5B,CCL27,UTS2,POMCB,NMUR1,RGR,OPN1MW2,PYY,AGT,NPFFR2 |
| Neuroactive ligand-receptor interaction | GZMA,PRLHR2A,TAAR8B,PTGIR,LEPR,LPAR4,GRM4,DRD2A,P2RY8,TAAR7F |
| Amine ligand-binding receptors | DRD3,HRH3,ADRB3,DRD1,ADRA2C,CHRM5,CHRM3,CHRM1,ADRA2B,DRD4 |
| Signal Transduction | RNF146,ADH8A,SPOPL,DHRS3A,ABCA4A,FGFBP1,NCKIPSD,TRIM33,WDR35,RAB6A |
Protein Function
Taar1 has several biochemical functions, for example, G-protein coupled receptor activity,trace-amine receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Taar1 itself. We selected most functions Taar1 had, and list some proteins which have the same functions with Taar1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| trace-amine receptor activity | TAAR8A,TAAR13E,TAAR12E,TAAR4,TAAR12C,TAAR2,TAAR14B,TAAR7D,TAAR11,TAAR15 |
| G-protein coupled receptor activity | OR5B2,GPR15,GLP2R,OR13A1,S1PR1,NPFFR1L3,ACKR3B,NPFFR1L1,F2RL1.2,OLFR498 |
Interacting Protein
Taar1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Taar1 here. Most of them are supplied by our site. Hope this information will be useful for your research of Taar1.
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