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TADA2B

  • Official Full Name

    transcriptional adaptor 2B

  • Overview

    TADA2B functions as a transcriptional adaptor protein that potentiates transcription through coordination of histone;acetyltransferase (HAT) activity and by linking activation factors to basal transcriptional machinery (Barlev et al.,;2003 (PubMed 12972612)).
  • Synonyms

    TADA2B; transcriptional adaptor 2B; transcriptional adapter 2-beta; MGC21874; ADA2 beta; ADA2 like protein beta; ADA2B; MGC21874 protein; TAD 2B; TAD2 beta; TAD2B; Transcriptional adapter 2 beta; transcriptional adaptor 2; yeast ADA2 homolog beta; ADA2-beta; OTTHUMP00000217249; OTTHUMP00000217250; ADA2-like protein beta; transcriptional adaptor 2 (ADA2 homolog, yeast)-beta; ADA2(beta);
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TADA2B-3097H Recombinant Human TADA2B, His-tagged E.coli His C-term-206aa
Human TADA2B-4343H Recombinant Human TADA2B Protein, GST-tagged Wheat Germ GST
Zebrafish TADA2B-3041Z Recombinant Zebrafish TADA2B Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • TADA2B Related Articles

TADA2B involved in several pathways and played different roles in them. We selected most pathways TADA2B participated on our site, such as Chromatin modifying enzymes, Chromatin organization, Direct p53 effectors, which may be useful for your reference. Also, other proteins which involved in the same pathway with TADA2B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Chromatin modifying enzymesKDM5D;PRMT6;SMYD3;VPS72;MTA2;KDM5BA;ATXN7;TAF6L;MSL2A
Chromatin organizationMBD3;RBBP7;DR1;SMARCB1B;MCRS1;KAT7;PRMT7;JHDM1D;ARID2
Direct p53 effectorsAIFM2;BCL2L14;CD82;GADD45A;HIC1;RNF144B;DUSP1;TRIAP1;ARID3A
HATs acetylate histonesZZZ3;ING5B;ATXN7L3;MSL3;DR1;EP400;C3orf75;KANSL3;JADE1

TADA2B has several biochemical functions, for example, DNA binding, chromatin binding, contributes_to histone acetyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TADA2B itself. We selected most functions TADA2B had, and list some proteins which have the same functions with TADA2B. You can find most of the proteins on our site.

Function Related Protein
DNA bindingRXRAB;PRRX1B;ZFP280D;BARHL1A;RB1;NKX6.2;MB21D1;TAF4B;STAT2
chromatin bindingAPTX;TOX3;CCNT1;NSD1;SAFB;TADA2A;SETD7;HMGB3A;ARX
contributes_to histone acetyltransferase activityKAT5;TAF6L;SUPT7L;KAT2A;TADA2B;TAF9;TAF5L;TADA2A;TAF10
transcription coactivator activityTADA2A;SETD3;CARM1;MAML2;TAF1;MED21;MKL1B;SAP130;KAT2A
transcription factor activity, sequence-specific DNA bindingHIVEP2;SOX3;ZNF323;TFDP1A;FOXP2;ZFP821;PLAGX;DBPB;EGR4
zinc ion bindingTRIML1;TRIM8;RNF166;RNF130;TRIM29;RASGRP1;ZDHHC3;Shh;UBR1

TADA2B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TADA2B here. Most of them are supplied by our site. Hope this information will be useful for your research of TADA2B.

USP22; CCDC101; TRRAP

Goulet, ML; Olagnier, D; et al. Systems Analysis of a RIG-I Agonist Inducing Broad Spectrum Inhibition of Virus Infectivity. PLOS PATHOGENS 9:-(2013).
Kornet, N; Scheres, B; et al. Members of the GCN5 Histone Acetyltransferase Complex Regulate PLETHORA-Mediated Root Stem Cell Niche Maintenance and Transit Amplifying Cell Proliferation in Arabidopsis. PLANT CELL 21:1070-1079(2009).
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