TBL1XR1
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Official Full Name
transducin (beta)-like 1 X-linked receptor 1 -
Overview
The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. -
Synonyms
TBL1XR1;transducin (beta)-like 1 X-linked receptor 1;transducin (beta) like 1X linked receptor 1;F-box-like/WD repeat-containing protein TBL1XR1;C21;DC42;FLJ12894;IRA1;TBLR1;TBL1-related protein 1;transducin beta-like 1X-related protein 1;nucle
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TBL1XR1-16514M | Recombinant Mouse TBL1XR1 Protein | Mammalian Cells | Mouse | His |
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| TBL1XR1-3020C | Recombinant Chicken TBL1XR1 | Mammalian Cells | Chicken | His |
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| TBL1XR1-424H | Recombinant Human TBL1XR1 Protein, His-tagged | E.coli | Human | His |
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| TBL1XR1-9048M | Recombinant Mouse TBL1XR1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| TBL1XR1-9048M-B | Recombinant Mouse TBL1XR1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
TBL1XR1 involved in several pathways and played different roles in them. We selected most pathways TBL1XR1 participated on our site, such as Wnt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with TBL1XR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Wnt signaling pathway | RAC3,PRICKLE1A,FZD9,FBXW11B,PPARDB,TLE3A,LRP5,RBX1,NLK2,PRKCBA |
Protein Function
TBL1XR1 has several biochemical functions, for example, DNA binding,beta-catenin binding,histone binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TBL1XR1 itself. We selected most functions TBL1XR1 had, and list some proteins which have the same functions with TBL1XR1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcription corepressor activity | KCTD1,SAP30,CRYM,EID1,PPP1R13L,ALX1,PFDN5,ZHX2,MNT,E2F6 |
| DNA binding | CDK5R2,ZNF558,SIX1B,HDGFRP2,SET,IKZF1,HIST1H2BN,HER4.3,PAX2,HSF5 |
| beta-catenin binding | SMAD3,NUMB,PTPRK,CDH24,APC,SHROOM2,DACT2,PXN,TCF7,ESR1 |
| transcription regulatory region DNA binding | GABPB2,POU5F1,GRHL1,DHX36,CARM1,RFX3,BCL11AA,TFAP2A,BRCA1,SNCA |
| histone binding | Ctsl,HIST1H4E,TBL1X,SART3,SIRT1,SUPT6H,UHRF1,HIST1H4A,ELP2,HIST1H4K |
| protein binding | FAM32A,RORC,CHST13,CCDC50,RPRD1B,PLEK,GOLGA7,RINL,TAF1A,MCM4 |
| protein N-terminus binding | ERCC2,KCNIP2,VWF,GTF2H2,EIF3E,TDRD7,EXOC4,ZWINT,NBN,SMARCE1 |
Interacting Protein
TBL1XR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TBL1XR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TBL1XR1.
Sox2;Ywhae;Nanog;Rnf2
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