TBXA2R

  • Official Full Name

    thromboxane A2 receptor

  • Overview

    This gene encodes a member of the G protein-coupled receptor family. The protein interacts with thromboxane A2 to induce platelet aggregation and regulate hemostasis. A mutation in this gene results in a bleeding disorder. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    TBXA2R; thromboxane A2 receptor; Prostanoid TP receptor; TP receptor; TXA2 R; TXA2R; TXA2-R; BDPLT13;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Bos taurus (Bovine)
  • Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • Zebrafish
  • E.coli
  • E.coli expression system
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • His|T7
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TBXA2R-8092H Recombinant Human TBXA2R protein, His & T7-tagged E.coli His/T7
Human TBXA2R-1197HCL Recombinant Human TBXA2R 293 Cell Lysate HEK293 N/A
Human TBXA2R-6403H Recombinant Human TBXA2R Protein (Pro3-Ser324), N-His tagged E.coli N-His
Mouse TBXA2R-16536M Recombinant Mouse TBXA2R Protein Mammalian Cell His
Mouse TBXA2R-9065M-B Recombinant Mouse TBXA2R Protein Pre-coupled Magnetic Beads HEK293
Mouse TBXA2R-9065M Recombinant Mouse TBXA2R Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat TBXA2R-5978R Recombinant Rat TBXA2R Protein Mammalian Cell His
Rat TBXA2R-5637R-B Recombinant Rat TBXA2R Protein Pre-coupled Magnetic Beads HEK293
Rat TBXA2R-5637R Recombinant Rat TBXA2R Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Bos taurus (Bovine) RFL30738BF Recombinant Full Length Bovine Thromboxane A2 Receptor(Tbxa2R) Protein, His-Tagged E.coli expression system His
Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops) RFL24034CF Recombinant Full Length Chlorocebus Aethiops Thromboxane A2 Receptor(Tbxa2R) Protein, His-Tagged E.coli expression system His
Homo sapiens (Human) RFL5715HF Recombinant Full Length Human Thromboxane A2 Receptor(Tbxa2R) Protein, His-Tagged E.coli expression system His
Mus musculus (Mouse) RFL14502MF Recombinant Full Length Mouse Thromboxane A2 Receptor(Tbxa2R) Protein, His-Tagged E.coli expression system His
Rattus norvegicus (Rat) RFL18678RF Recombinant Full Length Rat Thromboxane A2 Receptor(Tbxa2R) Protein, His-Tagged E.coli expression system His
Zebrafish TBXA2R-8384Z Recombinant Zebrafish TBXA2R Mammalian Cell His
Kit-0950 TR-FRET ROR alpha Coactivator Assay Kit, goat N/A
Kit-1536 TBXA2R U2OS β-Arrestin GPCR Assay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • TBXA2R Related Articles
  • TBXA2R Related Research Area

TBXA2R involved in several pathways and played different roles in them. We selected most pathways TBXA2R participated on our site, such as Calcium signaling pathway, Neuroactive ligand-receptor interaction, Platelet activation, which may be useful for your reference. Also, other proteins which involved in the same pathway with TBXA2R were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Calcium signaling pathwayGNAL;STIM1A;PRKCBA;PLCB4;CALM;ADRB1;PTK2B;CCKBR;EDNRA
Neuroactive ligand-receptor interactionMAS1;GHSR;GLRA3;AVPR2;LOC100328615;P2RX3A;P2RY11;GRIN2D;CSH2
Platelet activationFCER1G;PIK3CA;MAPK12;COL27A1;PIK3R2;GP6;ITGA2B;FCGR2A;ITGA2

TBXA2R has several biochemical functions, for example, guanyl-nucleotide exchange factor activity, protein binding, thromboxane A2 receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TBXA2R itself. We selected most functions TBXA2R had, and list some proteins which have the same functions with TBXA2R. You can find most of the proteins on our site.

Function Related Protein
guanyl-nucleotide exchange factor activityEIF2B5;ARHGEF4;RASGEF1C;VAV3;ARHGEF7;ITSN2A;FGD1;RASGRP2;DIS3
protein bindingEXOSC8;AKAP17A;LARP7;LAGE3;KEL;PRR13;SPOP;SLC30A1;RAPGEF3
thromboxane A2 receptor activityTBXAS1;TBXA2R

TBXA2R has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TBXA2R here. Most of them are supplied by our site. Hope this information will be useful for your research of TBXA2R.

PRDX4; GPRASP1; q81y32_bacan; CANX

Lin, H; Li, HF; et al. Thromboxane A2 Mediates Iron-Overload Cardiomyopathy in Mice Through Calcineurin-Nuclear Factor of Activated T Cells Signaling Pathway. CIRCULATION JOURNAL 77:2586-2595(2013).
Himmerich, H; Schmidt, L; et al. Impact of Clozapine, N-Desmethylclozapine and Chlorpromazine on Thromboxane Production in Vitro. MEDICINAL CHEMISTRY 8:1032-1038(2012).
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