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TIPARP

  • Official Full Name

    TCDD-inducible poly(ADP-ribose) polymerase

  • Overview

    This gene encodes a member of the poly(ADP-ribose) polymerase superfamily. Studies of the mouse ortholog have shown that the encoded protein catalyzes histone poly(ADP-ribosyl)ation and may be involved in T-cell function. Alternative splicing results in multiple transcript variants.
  • Synonyms

    TIPARP; TCDD-inducible poly(ADP-ribose) polymerase; TCDD-inducible poly [ADP-ribose] polymerase; DDF1; DKFZP434J214; DKFZp686N0351; PARP 1; PARP 7; PARP7; pART14; RM1; poly [ADP-ribose] polymerase 7; FLJ40466; DKFZp686P1838;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Zebrafish
  • HEK293
  • In Vitro Cell Free System
  • Insect Cell
  • Mammalian Cell
  • Sf9 Insect Cell
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TIPARP-436H Recombinant Human TIPARP, GST-tagged Sf9 Insect Cell GST
Human TIPARP-29527TH Recombinant Human TIPARP N/A
Human TIPARP-33H Recombinant Human TIPARP Protein, GST-tagged Wheat Germ GST 1-657 a.a.
Human TIPARP-6797HF Recombinant Full Length Human TIPARP Protein, GST-tagged In Vitro Cell Free System GST 166 amino acids
Human TIPARP-298H Active Recombinant Human TIPARP Protein, Flag-tagged Insect Cell Flag 400-657
Mouse TIPARP-16803M Recombinant Mouse TIPARP Protein Mammalian Cell His
Mouse TIPARP-9227M-B Recombinant Mouse TIPARP Protein Pre-coupled Magnetic Beads HEK293
Mouse TIPARP-9227M Recombinant Mouse TIPARP Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish TIPARP-4093Z Recombinant Zebrafish TIPARP Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • TIPARP Related Articles
  • TIPARP Related Research Area

TIPARP involved in several pathways and played different roles in them. We selected most pathways TIPARP participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TIPARP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

TIPARP has several biochemical functions, for example, NAD+ ADP-ribosyltransferase activity, enhancer binding, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TIPARP itself. We selected most functions TIPARP had, and list some proteins which have the same functions with TIPARP. You can find most of the proteins on our site.

Function Related Protein
NAD+ ADP-ribosyltransferase activityPARP6;GIG2O;PARP11;GIG2G;CHAT2;TIPARP;PARP12A;PARP2;GIG2P
enhancer bindingSMAD2;TIPARP;TCF3;MESP1;LEF1;AHR;ARNT;SMAD3;ELL3
metal ion bindingCSRP1B;GART;ZNF367;GGPS1;FDX1B;FTR43;NOB1;IDO2;TAX1BP1

TIPARP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TIPARP here. Most of them are supplied by our site. Hope this information will be useful for your research of TIPARP.

XRN2

MacPherson, L; Ahmed, S; et al. Aryl Hydrocarbon Receptor Repressor and TiPARP (ARTD14) Use Similar, but also Distinct Mechanisms to Repress Aryl Hydrocarbon Receptor Signaling. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 15:7939-7957(2014).
Diani-Moore, S; Zhang, S; et al. Aryl Hydrocarbon Receptor Activation by Dioxin Targets Phosphoenolpyruvate Carboxykinase (PEPCK) for ADP-ribosylation via 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-inducible Poly(ADP-ribose) Polymerase (TiPARP). JOURNAL OF BIOLOGICAL CHEMISTRY 288:21514-21525(2013).
  • Q&As
  • Reviews

Q&As (5)

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How does TIPARP contribute to the modulation of cellular energy metabolism? 02/04/2021

TIPARP interacts with key regulators of cellular metabolism, influencing processes such as glycolysis and mitochondrial function.

Can TIPARP expression levels serve as a biomarker for DNA damage response efficiency? 09/15/2020

TIPARP expression levels may serve as a potential biomarker for the efficiency of DNA damage response pathways in certain cellular contexts.

How does TIPARP participate in the regulation of the cell cycle? 05/26/2019

TIPARP's involvement in DNA repair processes can indirectly influence cell cycle progression by affecting the resolution of DNA lesions.

How does TIPARP participate in the regulation of DNA repair pathways? 03/29/2019

TIPARP suppresses PARP1 activity, influencing the choice between DNA repair pathways, such as homologous recombination and non-homologous end joining.

Can you explain the role of TIPARP in the ADP-ribosylation process? 12/11/2018

TIPARP negatively regulates ADP-ribosylation by binding to and inhibiting PARP1, thereby modulating the cellular response to DNA damage.

Customer Reviews (3)

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Reviews
03/05/2021

    Impressed with the efficiency of the delivery process; the package arrived intact and on schedule.

    07/12/2020

      This product consistently delivers high-quality results, making it an indispensable tool in our lab.

      11/17/2018

        The quality control measures are evident in the performance of this product.

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