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Official Full Name transmembrane protein 27
Background This gene encodes a type 1 transmembrane protein that is important for trafficking amino acid transporters to the apical brush border of proximal tubules. The encoded protein binds to amino acid transporters and regulates their expression on the plasma membrane. It also plays a role in controlling insulin exocytosis by regulating formation of the SNARE (soluble N-ethylmaleimide-sensitive-factor attachment protein receptor) complex in pancreatic beta cells. The extracellular domain of the encoded protein may be cleaved and shed from the plasma membrane specifically in pancreatic beta cells. [provided by RefSeq, Jun 2013]
Synonyms TMEM27; transmembrane protein 27; NX17; NX-17; collectrin; kidney-specific membrane protein;
    • Species :
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • Human Cell
    • Mammalian Cell
    • Tag :
    • Fc
    • His
    • GST
    • T7
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human TMEM27-1163HCL Recombinant Human TMEM27 cell lysate Human Cell N/A
    Human TMEM27-1782H Recombinant Human TMEM27 protein, His-tagged E.coli His
    Human TMEM27-528H Recombinant Human TMEM27 Protein, His-tagged HEK293 His
    Human TMEM27-8571H Recombinant Human TMEM27, Fc tagged Human Cell Fc
    Mouse Tmem27-1783M Recombinant Mouse Tmem27 protein, His & GST-tagged E.coli His/GST
    Mouse Tmem27-1784M Recombinant Mouse Tmem27 protein, His & T7-tagged E.coli His/T7
    Rat Tmem27-1785R Recombinant Rat Tmem27 protein, His & T7-tagged E.coli His/T7
    Rat TMEM27-6161R Recombinant Rat TMEM27 Protein Mammalian Cell His
    Rhesus Macaque TMEM27-4818R Recombinant Rhesus monkey TMEM27 Protein, His-tagged Mammalian Cell His

    tmem27 involved in several pathways and played different roles in them. We selected most pathways tmem27 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with tmem27 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    tmem27 has several biochemical functions, for example, metallopeptidase activity, peptidyl-dipeptidase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by tmem27 itself. We selected most functions tmem27 had, and list some proteins which have the same functions with tmem27. You can find most of the proteins on our site.

    Function Related Protein
    metallopeptidase activity ADAM9; HE1B; NPSN; ADAMTSL1; ACY1; BMP1; Npepo; PAPPA; AGBL1; C6AST4
    peptidyl-dipeptidase activity TMEM27; ACE
    protein binding GLTP; C9orf86; STAU1; NDRG4; CTGF; BIN1; CDC34; SCRN2; CD63; NOX1

    tmem27 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with tmem27 here. Most of them are supplied by our site. Hope this information will be useful for your research of tmem27.


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