Active Recombinant Mouse Fn-14, Fc-tagged
Cat.No. : | Tnfrsf12a-42M |
Product Overview : | Produced in HEK 293 cells. The extracellular domain of mouse Fn14 (aa 1-75) is fused to the Fc portion of human IgG1. |
- Specification
- Gene Information
- Related Products
Source : | HEK 293 cells |
Species : | Mouse |
Tag : | Fc |
Form : | Lyophilized. Contains PBS. Reconstitute with 50 μL of sterile water for a 1 mg/mL solution. Further dilutions should be made with medium containing 5% fetal calf serum. After reconstitution, prepare aliquots and store at -20°C. |
Bio-activity : | Inhibits TWEAK-mediated killing of Kym-1 target cells. Binds to human and mouse TWEAK. |
Molecular Mass : | ~34 kDa as determined by SDS-PAGE |
Endotoxin : | <0.1 eu/μg of purified protein (lal test).>0.1> |
Purity : | >95% as determined by SDS-PAGE. |
Usage : | For in vitro research use only. Not for use in diagnostics or in humans. |
Storage : | Store at -20°C. After reconstitution, prepare aliquots and store at -20°C. |
Warning : | No warranties, expressed or implied, are made regarding the use of this product. Creative Biomart is not liable for any damage, personal injury, or economic loss caused by this product. |
Gene Name : | Tnfrsf12a tumor necrosis factor receptor superfamily, member 12a [ Mus musculus ] |
Official Symbol : | Tnfrsf12a |
Synonyms : | TNFRSF12A; tumor necrosis factor receptor superfamily, member 12a; tumor necrosis factor receptor superfamily member 12A; tweak-receptor; FGF-inducible 14; type I transmembrane protein Fn14; fibroblast growth factor regulated protein 2; fibroblast growth factor-regulated protein 2; fibroblast growth factor-inducible immediate-early response protein 14; Fn14; HPIP; C87282; TweakR; TWEAK-R; AI255180; |
Gene ID : | 27279 |
mRNA Refseq : | NM_001161746 |
Protein Refseq : | NP_001155218 |
Pathway : | Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; |
Function : | protein binding; receptor activity; |
Products Types
◆ Recombinant Protein | ||
TNFRSF12A-471H | Recombinant Human TNFRSF12A Protein, Fc-tagged | +Inquiry |
TNFRSF12A-312H | Recombinant Active Human TNFRSF12A Protein (ECD), Fc-His-tagged(C-ter) | +Inquiry |
TNFRSF12A-1646R | Recombinant Rhesus Monkey TNFRSF12A Protein, hIgG1 tagged | +Inquiry |
TNFRSF12A-441H | Recombinant Human TNFRSF12A Protein, His&GST-tagged | +Inquiry |
TNFRSF12A-582H | Recombinant Human TNFRSF12A protein | +Inquiry |
◆ Lysates | ||
TNFRSF12A-1560HCL | Recombinant Human TNFRSF12A cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
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Q&As (5)
Ask a questionSome studies suggest that TNFRSF12A may play a role in cardiovascular diseases, and targeting it could be a potential therapeutic strategy, but more research is needed.
Research indicates that elevated levels of TNFRSF12A may serve as a diagnostic marker for certain cancers, providing valuable information for disease detection.
As of now, there are no FDA-approved drugs specifically targeting TNFRSF12A. However, research is ongoing to develop targeted therapies.
TNFRSF12A is known to modulate inflammatory responses, and dysregulation of its signaling pathways may contribute to chronic inflammatory conditions.
TNFRSF12A is being explored as a potential target for immunotherapy in cancer, with studies investigating its role in modulating the immune response.
Customer Reviews (3)
Write a reviewThe manufacturer's commitment to delivering excellent technical support further enhances the experience, offering timely resolutions to any challenges I may encounter.
the TNFRSF12A protein surpasses expectations in terms of quality, meeting the rigorous demands of my experiments.
With the TNFRSF12A protein and the manufacturer's support, I can confidently pursue my research goals and achieve meaningful outcomes.
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