Recombinant Human TNFRSF12A, Fc-tagged

• Cat.No.: TNFRSF12A-30125TH
• Product Overview: Recombinant fragment corresponding to amino acids 28-75 of Human TWEAKRfused at the C-terminus to the Fc portion of Human IgG1; MWt 35 kDa .

Specification

• Description: Tumor necrosis factor receptor superfamily member 12A is a protein that in humans is encoded by the TNFRSF12A gene.
• Protein length: 48 amino acids
• Conjugation: Fc
• Molecular Weight: 35.000kDa inclusive of tags
• Source: HEK 293 cells
• Tissue specificity: Highly expressed in heart, placenta and kidney. Intermediate expression in lung, skeletal muscle and pancreas.
• Form: Lyophilised:Reconstitute with 50μl sterile water to give a final concentration of 1mg/ml. After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. PBS containing at least 0.1% BSA should be used for further dilutions.
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: PBS
• Storage: Shipped at 4°C. Store at -20oC.
• Sequence Similarities: Contains 1 TNFR-Cys repeat.

Gene Information

• Gene Name: TNFRSF12A tumor necrosis factor receptor superfamily, member 12A [ Homo sapiens ]
• Official Symbol: TNFRSF12A
• Synonyms: TNFRSF12A; tumor necrosis factor receptor superfamily, member 12A; tumor necrosis factor receptor superfamily member 12A; CD266; FN14; TweakR
• Gene ID: 51330
• mRNA Refseq: NM_016639
• Protein Refseq: NP_057723
• MIM: 605914
• Uniprot ID: Q9NP84
• Chromosome Location: 16p13.3
• Pathway: Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem
• Function: protein binding; receptor activity