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TNKS2

Official Full Name

tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
Synonyms

TNKS2; tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2; tankyrase-2; PARP 5b; PARP 5c; PARP5B; PARP5C; pART6; TANK2; TNKL; TNKS-2; tankyrase 2; tankyrase II; tankyrase-like protein; tankyrase-related protein; poly [ADP-ribose] polymerase 5B; TRF1-interacting ankyrin-related ADP-ribose polymerase 2; PARP-5b; PARP-5c;

Type:
Assay Kits
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species :
Chicken
Human
Mouse
Rhesus Macaque

Source :
E.coli
HEK293
Mammalian Cell
Wheat Germ

Tag :
GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Price
	Kit-1884	TNKS2 Histone Ribosylation Assay Kit (Antibody Detection) I		N/A	Inquiry
	Kit-1887	TNKS2 Histone Ribosylation Assay Kit (Biotin-labeled NAD+) II		N/A	Inquiry
	Kit-1886	TNKS2 Histone Ribosylation Assay Kit (Biotin-labeled NAD+) I		N/A	Inquiry
	Kit-1885	TNKS2 Histone Ribosylation Assay Kit (Antibody Detection) II		N/A	Inquiry
	Kit-1888	TNKS2 Histone Ribosylation Colorometric Assay Kit		N/A	Inquiry
Chicken	TNKS2-5913C	Recombinant Chicken TNKS2	Mammalian Cell	His	Inquiry
Human	TNKS2-8199H	Recombinant Human TNKS2 protein, His-tagged	E.coli	His	Inquiry
Human	TNKS2-3329H	Recombinant Human TNKS2 protein, GST-tagged	Wheat Germ	GST	Inquiry
Human	TNKS2-3328H	Recombinant Human TNKS2, GST-tagged	E.coli	GST	$319.00 / 25ug
Mouse	TNKS2-9492M-B	Recombinant Mouse TNKS2 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Mouse	TNKS2-17189M	Recombinant Mouse TNKS2 Protein	Mammalian Cell	His	Inquiry
Mouse	TNKS2-9492M	Recombinant Mouse TNKS2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	$2,998.00 / 50ug
Rhesus Macaque	TNKS2-4693R	Recombinant Rhesus Macaque TNKS2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	$2,998.00 / 50ug
Rhesus Macaque	TNKS2-4693R-B	Recombinant Rhesus Macaque TNKS2 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Rhesus Macaque	TNKS2-4879R	Recombinant Rhesus monkey TNKS2 Protein, His-tagged	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein
TNKS2 Related Research Area

TNKS2 involved in several pathways and played different roles in them. We selected most pathways TNKS2 participated on our site, such as Degradation of AXIN, Disease, Diseases of signal transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with TNKS2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Degradation of AXIN	TNKS;TNKS2;RNF146
Disease	TTR;ELL;TCEA1;HEY1;CCDC167;gag;KREMEN2;AP2A1;CFTR
Diseases of signal transduction	OPN1SW;KREMEN1;HEY1;CDK8;TNKS2;OS9;OPN1MW;STRA6;DERL2
Signal Transduction	RBP4;IFT122;NPSR1;PTHRP2;CCNT2A;KAL1A;ARHGEF17;CDON;OXGR1A.3
Signaling by WNT in cancer	RNF43;KREMEN2;TNKS2;TNKS;KREMEN1
Signaling by Wnt	HECW1;C;TMED5;LGR4;SOX32;RSPO3;RYK;LGR6;RBBP5
TCF dependent signaling in response to WNT	RNF146;SRY;RSPO4;ZNRF3;TNKS2;ASH2L;LEO1;TLE3B;DACT1
XAV939 inhibits tankyrase, stabilizing AXIN

TNKS2 has several biochemical functions, for example, NAD+ ADP-ribosyltransferase activity, enzyme binding, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TNKS2 itself. We selected most functions TNKS2 had, and list some proteins which have the same functions with TNKS2. You can find most of the proteins on our site.

Function	Related Protein
NAD+ ADP-ribosyltransferase activity	GIG2E;GIG2O;GIG2D;ART5;ZC3HAV1;PARP12A;PARP16;PARP11;GIG2Q
enzyme binding	DYM;MLL5;KDM4C;CA;ABCD1;MTA1;TOP2B;RCOR2;LAMP2
metal ion binding	PRKCHA;TKTL1;CENPT;ZNF136;CYP4A14;NAALADL1;OAS3;ZNF330;CYP4T8
protein binding	RNF126;MRC2;ZNF830;NIP7;ITGB1;IL10RA;IL17F;DHX36;ZFP36L1

TNKS2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TNKS2 here. Most of them are supplied by our site. Hope this information will be useful for your research of TNKS2.

Sh3bp2; SH3BP2; BCR; RAD54L; BABAM1

ADP-ribosyltransferases (ARTs)