TNKS2 Protein

TNKS2

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TNKS2

Official Full Name tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
Synonyms TNKS2; tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2; tankyrase-2; PARP 5b; PARP 5c; PARP5B; PARP5C; pART6; TANK2; TNKL; TNKS-2; tankyrase 2; tankyrase II; tankyrase-like protein; tankyrase-related protein; poly [ADP-ribose] polymerase 5B; TRF1-interacting ankyrin-related ADP-ribose polymerase 2; PARP-5b; PARP-5c
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rhesus Macaque
    • Source :
    • E.coli
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human TNKS2-3328H Recombinant Human TNKS2, GST-tagged E.coli GST
    Human TNKS2-3329H Recombinant Human TNKS2 protein, GST-tagged Wheat Germ GST
    Human TNKS2-8199H Recombinant Human TNKS2 protein, His-tagged E.coli His
    Mouse TNKS2-17189M Recombinant Mouse TNKS2 Protein Mammalian Cell His
    Rhesus Macaque TNKS2-4879R Recombinant Rhesus monkey TNKS2 Protein, His-tagged Mammalian Cell His
    Chicken TNKS2-5913C Recombinant Chicken TNKS2 Mammalian Cell His
    Kit-1884 TNKS2 Histone Ribosylation Assay Kit (Antibody Detection) I N/A
    Kit-1885 TNKS2 Histone Ribosylation Assay Kit (Antibody Detection) II N/A
    Kit-1886 TNKS2 Histone Ribosylation Assay Kit (Biotin-labeled NAD+) I N/A
    Kit-1887 TNKS2 Histone Ribosylation Assay Kit (Biotin-labeled NAD+) II N/A
    Kit-1888 TNKS2 Histone Ribosylation Colorometric Assay Kit N/A

    TNKS2 involved in several pathways and played different roles in them. We selected most pathways TNKS2 participated on our site, such as Degradation of AXIN, Disease, Diseases of signal transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with TNKS2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Degradation of AXIN TNKS; TNKS2; RNF146
    Disease CCDC167; NPM1; TLR10; FMOD; AP1G1; TAF1L; PPIA; IPO5; VPS37A; CHMP4C
    Diseases of signal transduction CDK8; HDAC5; FGFR1OP; TNKS; HEY1; RLBP1; MYO18A; TRIM24; STRA6; OPN1MW2
    Signal Transduction DISP2; ARHGAP28; RGS7; USP9X; RSPO3; KAL1; DHRS3A; ARHGEF17; PTH; TJP2B
    Signaling by WNT in cancer KREMEN2; RNF43; KREMEN1; TNKS; TNKS2
    Signaling by Wnt RNF146; FAM123B; USP34; TNKS2; RNF43; SRY; KREMEN1; RBBP5; WIF1; CBY1
    TCF dependent signaling in response to WNT WIF1; DACT1; USP34; RSPO3; CBY1; LEO1; RSPO1; ZNRF3; C; RSPO4
    XAV939 inhibits tankyrase, stabilizing AXIN TNKS2

    TNKS2 has several biochemical functions, for example, NAD+ ADP-ribosyltransferase activity, enzyme binding, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TNKS2 itself. We selected most functions TNKS2 had, and list some proteins which have the same functions with TNKS2. You can find most of the proteins on our site.

    Function Related Protein
    NAD+ ADP-ribosyltransferase activity PARP1; GIG2D; CHAT1; GIG2G; GIG2F; SIRT4; PARP15; TNKS; PARP2; SIRT6
    enzyme binding SLC18A1; DDX5; Ar; CASP2; CTNNB1; UGT1A6B; TNKS2; P4HB; HMOX1; AXIN2
    metal ion binding PRPSAP2; NEK11; HPX; ITGAM; ZNF114; ZFPM1; ZNF398; PLD6; ISL2B; GNA12
    protein binding MMRN2; TLR2; KCNJ3; RGS3; IL1RN; MAP4; ACACA; GFI1B; FTH1; EN1

    TNKS2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TNKS2 here. Most of them are supplied by our site. Hope this information will be useful for your research of TNKS2.

    Sh3bp2; SH3BP2; BCR; RAD54L; BABAM1

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