• Official Full Name

    tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2

  • Synonyms

    TNKS2; tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2; tankyrase-2; PARP 5b; PARP 5c; PARP5B; PARP5C; pART6; TANK2; TNKL; TNKS-2; tankyrase 2; tankyrase II; tankyrase-like protein; tankyrase-related protein; poly [ADP-ribose] polymerase 5B; TRF1-interacting ankyrin-related ADP-ribose polymerase 2; PARP-5b; PARP-5c;
    • Type:
    • Assay Kits
    • Recombinant Proteins
    • Protein Pre-coupled Magnetic Beads
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • His (Fc)
    • Avi
    • N/A
    • Involved Pathway
    • Protein Function
    • Interacting Protein
    • TNKS2 Related Research Area

    TNKS2 involved in several pathways and played different roles in them. We selected most pathways TNKS2 participated on our site, such as Degradation of AXIN, Disease, Diseases of signal transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with TNKS2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Degradation of AXINTNKS;TNKS2;RNF146
    Diseases of signal transductionOPN1SW;KREMEN1;HEY1;CDK8;TNKS2;OS9;OPN1MW;STRA6;DERL2
    Signal TransductionRBP4;IFT122;NPSR1;PTHRP2;CCNT2A;KAL1A;ARHGEF17;CDON;OXGR1A.3
    Signaling by WNT in cancerRNF43;KREMEN2;TNKS2;TNKS;KREMEN1
    Signaling by WntHECW1;C;TMED5;LGR4;SOX32;RSPO3;RYK;LGR6;RBBP5
    TCF dependent signaling in response to WNTRNF146;SRY;RSPO4;ZNRF3;TNKS2;ASH2L;LEO1;TLE3B;DACT1
    XAV939 inhibits tankyrase, stabilizing AXIN

    TNKS2 has several biochemical functions, for example, NAD+ ADP-ribosyltransferase activity, enzyme binding, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TNKS2 itself. We selected most functions TNKS2 had, and list some proteins which have the same functions with TNKS2. You can find most of the proteins on our site.

    Function Related Protein
    NAD+ ADP-ribosyltransferase activityGIG2E;GIG2O;GIG2D;ART5;ZC3HAV1;PARP12A;PARP16;PARP11;GIG2Q
    enzyme bindingDYM;MLL5;KDM4C;CA;ABCD1;MTA1;TOP2B;RCOR2;LAMP2
    metal ion bindingPRKCHA;TKTL1;CENPT;ZNF136;CYP4A14;NAALADL1;OAS3;ZNF330;CYP4T8
    protein bindingRNF126;MRC2;ZNF830;NIP7;ITGB1;IL10RA;IL17F;DHX36;ZFP36L1

    TNKS2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TNKS2 here. Most of them are supplied by our site. Hope this information will be useful for your research of TNKS2.

    Sh3bp2; SH3BP2; BCR; RAD54L; BABAM1

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