TRAF7

  • Official Full Name

    TNF receptor-associated factor 7

  • Overview

    Tumor necrosis factor (TNF; see MIM 191160) receptor-associated factors, such as TRAF7, are signal transducers for members of the TNF receptor superfamily (see MIM 191190). TRAFs are composed of an N-terminal cysteine/histidine-rich region containing zinc RING and/or zinc finger motifs; a coiled-coil (leucine zipper) motif; and a homologous region that defines the TRAF family, the TRAF domain, which is involved in self-association and receptor binding.

  • Synonyms

    TRAF7;TNF receptor-associated factor 7;RFWD1, ring finger and WD repeat domain 1;E3 ubiquitin-protein ligase TRAF7;DKFZp586I021;MGC7807;RNF119;E3 ubiquitin protein ligase TRAF7;RFWD1;Ring finger and WD repeat domain 1;RING finger protein 119;TNF receptor associated factor 7;RING finger and WD repeat-containing protein 1

Recombinant Proteins

  • Chicken
  • Rhesus macaque
  • Zebrafish
  • Human
  • Mammalian Cells
  • HEK293
  • E. coli
  • His
  • Non
  • Avi
  • Fc
  • GST
Cat.# Product name Source (Host) Species Tag Protein Length Price
TRAF7-1903C Recombinant Chicken TRAF7 Mammalian Cells Chicken His
TRAF7-4935R Recombinant Rhesus monkey TRAF7 Protein, His-tagged Mammalian Cells Rhesus macaque His
TRAF7-5042Z Recombinant Zebrafish TRAF7 Mammalian Cells Zebrafish His
TRAF7-816HCL Recombinant Human TRAF7 293 Cell Lysate HEK293 Human Non
TRAF7-4749R Recombinant Rhesus Macaque TRAF7 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque Avi&Fc&His
TRAF7-4749R-B Recombinant Rhesus Macaque TRAF7 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
TRAF7-7863H Recombinant Human TRAF7 protein, GST-tagged E. coli Human GST

    Involved Pathway

    TRAF7 involved in several pathways and played different roles in them. We selected most pathways TRAF7 participated on our site, such as Adaptive Immune System,Antigen processing: Ubiquitination &amp,Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRAF7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Immune System CLEC5A,SIGLEC11,RNF144B,LAIR1,SLAMF6,DEFA6,C1rb,TRIM9,UBR1,TREM1
    Adaptive Immune System B2ML,CTSK,MGC174857,LAIR1,KIF4,KIF3B,TREML4,LILRA3,CD226,PVRL2L
    Proteasome degradation TRIM9,UBE2J2,SPSB2,ASB6,PJA2,TRIM69,ASB3,LTN1,FBXO44,ASB9
    Class I MHC mediated antigen processing &amp TRIM50,PJA2,RBCK1,ASB14,ASB13,HUWE1,KLHL20,FBXO17,HECTD3,RNF4
    Antigen processing: Ubiquitination &amp RNF123,RNF14,RNF25,TRIM41,FBXO3,HUWE1,ASB3,DTX3L,RNF220,WWP1
    presentation UBE2U,SEC24A,HUWE1,TRIM39,PJA1,CTSL2,UBR2,ASB6,CTSL1,FBXO44

    Protein Function

    TRAF7 has several biochemical functions, for example, ligase activity,protein binding,ubiquitin-protein transferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TRAF7 itself. We selected most functions TRAF7 had, and list some proteins which have the same functions with TRAF7. You can find most of the proteins on our site.

    Function Related Protein
    zinc ion binding TEX13A,RAG1,MAN2B1,GATA1,TLL2,RNF144B,NR2E3,RFWD2,RNF14,HE2
    ligase activity RNF123,NAPRT1,PELI2,MGRN1,TRIM11,UBE2D1A,RNF133,ACSF2,MARCH11,CBL
    protein binding TUB,UBTD1,RPLP1,ST8SIA5,CCNB3,LMX1A,PRPF40A,TMED1,XRCC4,MED1
    ubiquitin-protein transferase activity UBE2L6,MARCH5L,PDZRN3B,LRSAM1,TRIM71,TRAF4,HACE1,UBE2D2A,ITCH,ANKIB1A

    Interacting Protein

    TRAF7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRAF7 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRAF7.

    MAP3K3;Ripk4;HIP2;UBE2L6;UBE2D1;UBE2D2;UBE2L3;ampS;UBE2D4;MAP3K2

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