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Official Full Name tripartite motif containing 11
Background The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the nucleus and the cytoplasm. Its function has not been identified. [provided by RefSeq, Jul 2008]
Synonyms TRIM11; tripartite motif containing 11; BIA1; RNF92; E3 ubiquitin-protein ligase TRIM11; RING finger protein 92; tripartite motif-containing 11; tripartite motif-containing protein 11;
    • Species :
    • Human
    • Mouse
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • SUMO
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human TRIM11-1107H Recombinant Human TRIM11 Protein (267-468 aa), His-SUMO-tagged E.coli His/SUMO
    Human TRIM11-3405H Recombinant Human TRIM11, GST-tagged E.coli GST
    Human TRIM11-5907H Recombinant Human TRIM11 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human TRIM11-796HCL Recombinant Human TRIM11 293 Cell Lysate HEK293 N/A
    Mouse TRIM11-17339M Recombinant Mouse TRIM11 Protein Mammalian Cell His
    Mouse Trim11-6643M Recombinant Mouse Trim11 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Rhesus Macaque TRIM11-4952R Recombinant Rhesus monkey TRIM11 Protein, His-tagged Mammalian Cell His

    trim11 involved in several pathways and played different roles in them. We selected most pathways trim11 participated on our site, such as Adaptive Immune System, Antigen processing: Ubiquitination &amp, Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with trim11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adaptive Immune System UBR2; RNF34; RAET1E; UBA5; CD160; LAIR1; AKR1C1; CTSB; ICAM4; AP1M2
    Antigen processing: Ubiquitination &amp KLHL21; ASB13; RNF123; UBE2L6; TRIM11; UBR1; TRIM50; LTN1; UBE2E3; TPP2
    Proteasome degradation RNF6; TRIM63; RNF14; ATG7; RNF144B; FBXO27; DTX3L; VPRBP; RNF138; TRIM69
    Class I MHC mediated antigen processing &amp ASB13; RNF25; VPRBP; CYBA; RNF34; PJA2; RNF182; B2ML; WSB1; UBE2J2
    presentation ERAP1; ASB14; CMTM2A; TRIM41; ASB6; RNF25; KLHL21; RNF4; MKRN1; FBXO44
    Immune System CD160; LAIR1; CASP2; IgG3; TREML2; RAPGEF3; RAET1E; NA; CASP4; STIM1B

    trim11 has several biochemical functions, for example, ligase activity, protein binding, protein domain specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by trim11 itself. We selected most functions trim11 had, and list some proteins which have the same functions with trim11. You can find most of the proteins on our site.

    Function Related Protein
    ligase activity UBR1; RNF43; GLULC; TRIM17; TRIM50; MYLIP; TRAF6; SMURF2; UHRF1; BTRC
    protein binding UBXN8; RBP5; SGOL1; CECR2; TRPM8; EIF5; BIK; RAB11A; MYO5B; MXI1
    protein domain specific binding ARRB2; IGBP1; STXBP1; GNAI3; ETV6; HIST2H4A; GABRR3; YWHAZ; CASP2; TUBA1A
    transcription factor binding AGTR2; FOXA2; FHL2; AHR; DIP2C; FOS; CXXC5; DDIT3; HHEX; CRY1
    ubiquitin protein ligase activity ITCHA; HERC5; MED23; TRIM3; AMFR; PPIL2; UBE2J1; XIAP; TRIM32; UBE2G1B
    zinc ion binding RNF168; S100B; ING2; DDX41; MUL1A; RBM5; TRIM35-29; PGLYRP3; TRIM38; LIMCH1A

    trim11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with trim11 here. Most of them are supplied by our site. Hope this information will be useful for your research of trim11.

    MED15; UBA1; UBE2N; UBE2V1; PAX6; yngF; gpsA; RNF126; TRIM35; Smad6

    Di, K; Linskey, ME; et al. TRIM11 is overexpressed in high-grade gliomas and promotes proliferation, invasion, migration and glial tumor growth. ONCOGENE 32:5038-5047(2013).
    Lee, Y; Song, B; et al. TRIM11 Negatively Regulates IFN beta Production and Antiviral Activity by Targeting TBK1. PLOS ONE 8:-(2013).

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