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TRIM33

  • Official Full Name

    tripartite motif containing 33

  • Overview

    The protein encoded by this gene is thought to be a transcriptional corepressor. However, molecules that interact with this protein have not yet been identified. The protein is a member of the tripartite motif family. This motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. Three alternatively spliced transcript variants for this gene have been described, however, the full-length nature of one variant has not been determined. [provided by RefSeq, Jul 2008]
  • Synonyms

    TRIM33; tripartite motif containing 33; ECTO; PTC7; RFG7; TF1G; TIF1G; TIFGAMMA; TIF1GAMMA; E3 ubiquitin-protein ligase TRIM33; TIF1-gamma; protein Rfg7; ectodermin homolog; RET-fused gene 7 protein; tripartite motif-containing 33; transcriptional intermediary factor 1 gamma;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Zebrafish
  • Baculovirus-Insect cells
  • E.coli
  • HEK293
  • HEK293T
  • Insect Cell
  • Insect Cells
  • Mammalian Cell
  • Mammalian cells
  • Sf9 Insect Cell
  • DDK
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • His|Flag
  • Myc
  • N/A
  • N
  • TwinStrep
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TRIM33-227H Recombinant Human TRIM33 Protein, GST-tagged E.coli GST 885-1091
Human TRIM33-229H Recombinant Human TRIM33 Protein, GST-tagged E.coli GST 885-1074
Human TRIM33-230H Recombinant Human TRIM33 Protein, His-tagged E.coli His 885-1074
Human TRIM33-228H Recombinant Human TRIM33 Protein, His-tagged E.coli His 885-1091
Human TRIM33-506H Recombinant Human TRIM33 Protein, DDK-tagged Sf9 Insect Cell DDK
Human TRIM33-110H Recombinant Human TRIM33 Protein, His-tagged Insect Cell His
Human TRIM33-83H Recombinant Human TRIM33, His&FLAG-tagged E.coli His/Flag
Human TRIM33-781HCL Recombinant Human TRIM33 293 Cell Lysate HEK293 N/A
Human TRIM33-336H Recombinant Human TRIM33 Protein, Flag-tagged Insect Cells Flag
Human TRIM33-1584HFL Recombinant Full Length Human TRIM33 Protein, C-DDK-tagged Sf9 Insect Cell DDK
Human TRIM33-2258H Recombinant Human TRIM33 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human TRIM33-0114H Recombinant Human TRIM33 Protein (Met1-Lys1127), N-TwinStrep-tagged Baculovirus-Insect cells N-TwinStrep Met1-Lys1127
Human TRIM33-09HFL Recombinant Full Length Human TRIM33 Protein, C-Flag-tagged Mammalian cells Flag
Human TRIM33-2258H-B Recombinant Human TRIM33 Protein Pre-coupled Magnetic Beads HEK293
Mouse Trim33-6654M Recombinant Mouse Trim33 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Zebrafish TRIM33-859Z Recombinant Zebrafish TRIM33 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

TRIM33 involved in several pathways and played different roles in them. We selected most pathways TRIM33 participated on our site, such as Downregulation of SMAD2/3:SMAD4 transcriptional activity, Gene Expression, Generic Transcription Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIM33 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Downregulation of SMAD2/3:SMAD4 transcriptional activitySKIB;TRIM33;USP9X;RNF111;SKIA;SKILB;PARP1;SMAD3B;SKI
Gene ExpressionCCDC76;MBD3B;CCNT2A;CBX3;ZNF571;PIWIL4;GM3258;ZNF562;GLS2B
Generic Transcription PathwayCTGF;ZFP30;ZNF562;ZNF747;ZNF266;ZNF557;ESRRA;ZNF114;ZKSCAN3
Signal TransductionCBY1;NMS;SCT;FGD2;LGR4;ARHGAP33;SOX32;FGFBP1;PYY
Signaling by TGF-beta Receptor ComplexUSP9;UCHL5;PMEPA1;NEDD8;TRIM33;USP15;NEDD8L;USP9X;SKIA
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimerTRIM33;USP9X;USP9;SKIB;SKILB

TRIM33 has several biochemical functions, for example, DNA binding, R-SMAD binding, co-SMAD binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIM33 itself. We selected most functions TRIM33 had, and list some proteins which have the same functions with TRIM33. You can find most of the proteins on our site.

Function Related Protein
DNA bindingGSX1;ZNF446;DLX3B;H1M;ZSCAN4C;KIF4A;AHR2;RTEL1;PBX1
R-SMAD bindingPMEPA1;MEN1;ANKRD1;SMAD2;SMAD4;ZC3H3;AXIN1;ZEB2;FOS
co-SMAD bindingSMAD3;CITED1;FOXH1;TGIF1;GATA4;SMAD6;TRIM33;SMAD1;USP9X
ligase activityTRIM5;RNF217;TRIM22;RNF2;TRAIP;TMEM129;ATG10;PCXA;TRIM23
protein bindingNCBP2;STX2;TAP1;NUP62CL;CDK1;KCNJ6;EREG;ELANE;DNM1
ubiquitin-protein transferase activityRBBP6;BIRC5B;UBE2A;TRAF7;HACE1;BIRC5A;BIRC2;RC3H2;UBR1
zinc ion bindingNR1D4B;PRKCB;FBXO30;TRIM35-27;TRAF2;ZFAND1;TTF2;DIDO1;LHX1B

TRIM33 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIM33 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIM33.

SMAD4; SMAD2; gata1_human_gene; gata2_human_gene; TAL1; CDK9

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