TRIM50

  • Official Full Name

    tripartite motif containing 50

  • Synonyms

    TRIM50;tripartite motif containing 50;TRIM50A, tripartite motif containing 50 , tripartite motif containing 50A;E3 ubiquitin-protein ligase TRIM50;FLJ32804;E3 ubiquitin ligase;tripartite motif protein 50;tripartite motif-containing 50;tripartite

Recombinant Proteins

  • Mouse
  • Rat
  • Human
  • Mammalian Cells
  • HEK293
  • E. coli
  • His
  • DDK
  • Myc
  • Avi
  • Fc
  • GST

    Involved Pathway

    TRIM50 involved in several pathways and played different roles in them. We selected most pathways TRIM50 participated on our site, such as Adaptive Immune System,Antigen processing: Ubiquitination &amp,Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIM50 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Proteasome degradation ATG7,LTN1,FBXO44,RNF144B,FBXO17,TRIM41,RNF34,SPSB1,RNF14,RNF4
    Immune System CLEC6A,GRAP2B,LILRB3,DDX41,TRIM29,ACTR1A,IFIT10,RNF216,CTSO,BAIAP2
    Antigen processing: Ubiquitination &amp DTX3L,RNF19B,DZIP3,HUWE1,RNF34,TRIM11,TRIM63,UBE2L6,WWP1,RNF25
    Class I MHC mediated antigen processing &amp CTSL2,KLHL20,RNF6,FBXO17,SPSB1,CTSL1,RNF123,CTSS,FBXO44,BLMH
    Adaptive Immune System UBA5,CMTM2A,KLC3,CLEC2D,ASB18,WWP1,CD96,KIF2B,CTSL2,CHUK
    presentation RNF144B,DZIP3,PJA2,RNF138,NPEPPS,ASB2,TRIM41,ASB7,RNF6,CTSS

    Protein Function

    TRIM50 has several biochemical functions, for example, UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity,coenzyme F420-0 gamma-glutamyl ligase activity,coenzyme F420-2 alpha-glutamyl ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIM50 itself. We selected most functions TRIM50 had, and list some proteins which have the same functions with TRIM50. You can find most of the proteins on our site.

    Function Related Protein
    tubulin-glutamic acid ligase activity UBR1,SHRPRBCK1R,HECW2,MARCH9,NEURL1B,RNF144AB,RNF144AA,G2E3,MARCH6,MARCH11
    protein-glycine ligase activity, elongating RFWD2,ZNRF2B,ARIH1L,ZNRF3,MARCH6,RNF144AB,LTN1,RNF144AA,MUL1A,G2E3
    protein binding TCTEX1D2,PML,DCPS,PSMG2,TMEM190,DYNLL1,ACAA1,SCLY,TCEANC,FCN2
    ligase activity MARCH8,UCHL1,TTLL13,RNF25,PPIL2,RNF38,SHRPRBCK1R,NEDD4,PJA1,RFFL
    tubulin-glycine ligase activity ZNRF2B,G2E3,RNF144AA,TRIM71,MARCH5L,MYLIPB,SHRPRBCK1R,RC3H2,SIAH1A,MARCH4
    ribosomal S6-glutamic acid ligase activity UBE2IB,RAG1,RNF169,RFWD2,MARCH4,ZNRF2B,TMEM129,TRIM41,UBE2M,UBR1
    protein-glycine ligase activity RC3H2,LTN1,RNF149,UBR1,ITCHA,TMEM129,NEURL1B,NEURL3,UBE2IA,ZNRF3
    UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity RNF187,NEURL1B,MYLIPA,TRIM41,ZNRF2B,TRIM71,MARCH5L,MARCH9,MUL1A,RFWD2
    zinc ion binding ADAT3,APOBEC3D,SRSF7B,PHF21B,L3MBTL2,L3MBTL4,MAP3K1,DPYS,FBXO11,GCM1

    Interacting Protein

    TRIM50 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIM50 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIM50.

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