TRIM50

  • Official Full Name

    tripartite motif containing 50

  • Synonyms

    TRIM50;tripartite motif containing 50;TRIM50A, tripartite motif containing 50 , tripartite motif containing 50A;E3 ubiquitin-protein ligase TRIM50;FLJ32804;E3 ubiquitin ligase;tripartite motif protein 50;tripartite motif-containing 50;tripartite

Recombinant Proteins

  • Mouse
  • Rat
  • Human
  • Mammalian Cells
  • HEK293
  • E. coli
  • His
  • DDK
  • Myc
  • Avi
  • Fc
  • GST

    Involved Pathway

    TRIM50 involved in several pathways and played different roles in them. We selected most pathways TRIM50 participated on our site, such as Adaptive Immune System,Antigen processing: Ubiquitination &amp,Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIM50 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Class I MHC mediated antigen processing &amp ASB11,LRSAM1,TRIM39,B2ML,UBE2L6,TRAF7,DZIP3,SEC24A,CTSL1,SEC23A
    Adaptive Immune System OSBPL1A,CYBA,KIF15,AHCYL1,DCTN2,NPEPPS,TRIM41,RACGAP1,LILRB4,TREML2
    Proteasome degradation MKRN1,ASB2,DTX3L,UBE2F,UBE2E3,RBCK1,WWP1,ASB13,UBE2U,ATG7
    Immune System GBP2,ARIH1,KIF2A,DUSP3,Siglece,NLRP4,PANX1B,LILRB3,NLRP4E,RAET1E
    presentation FCGR1B,TRIM39,LRRC41,UBE2V1,NPEPPS,RBCK1,CD207,WWP1,SEC61B,GAN
    Antigen processing: Ubiquitination &amp LTN1,RNF111,ASB2,ASB3,SPSB1,UBE2L6,FBXO17,ASB14,RBCK1,RNF123

    Protein Function

    TRIM50 has several biochemical functions, for example, UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity,coenzyme F420-0 gamma-glutamyl ligase activity,coenzyme F420-2 alpha-glutamyl ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIM50 itself. We selected most functions TRIM50 had, and list some proteins which have the same functions with TRIM50. You can find most of the proteins on our site.

    Function Related Protein
    protein-glutamic acid ligase activity UBE2IA,SIAH1A,RNF187,HERC2,UBE2IB,MYLIPA,MYLIPB,NEURL3,DTX1,TMEM129
    tubulin-glutamic acid ligase activity MUL1A,RNF149,MYLIPA,ITCHA,TTLL1,SIAH2L,ZNRF3,UBE2IA,MYLIPB,RNF180
    metal ion binding ALOX12E,RBM27,PCK2,C1GALT1A,PFAS,CYP2F2,ADIPOR2,B3GNT1,ELAC2,FBP2
    ligase activity CBLC,UBE2G1B,GLULC,RNF152,FPGS,NAPRT1,HECW1B,TRIM11,NSMCE2,ZNRF2
    coenzyme F420-0 gamma-glutamyl ligase activity ARIH1L,TRIM41,MUL1A,UBE2IA,RNF144AA,NEURL1B,MARCH6,ZNRF3,SIAH2L,RNF169
    protein-glycine ligase activity, elongating G2E3,RNF180,MARCH5L,RC3H2,UBE2IB,ITCHA,NEURL3,RAG1,UBE2IA,DTX1
    UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity SIAH1A,HECW2,MARCH5L,UBE2IB,G2E3,SHRPRBCK1R,HERC2,DTX1,SIAH2L,MGRN1A
    protein-glycine ligase activity NEURL1B,RNF180,RNF144AA,TMEM129,MYLIPB,UBR1,RNF169,TRIM41,MYLIPA,RNF144AB
    tubulin-glycine ligase activity SIAH2L,RNF169,HERC2,G2E3,UBE2IB,ZNRF2B,ARIH1L,SHRPRBCK1R,DTX1,MGRN1A

    Interacting Protein

    TRIM50 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIM50 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIM50.

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