trim50

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trim50

Official Full Name tripartite motif containing 50
Synonyms TRIM50; tripartite motif containing 50; TRIM50A, tripartite motif containing 50 , tripartite motif containing 50A; E3 ubiquitin-protein ligase TRIM50; FLJ32804; E3 ubiquitin ligase; tripartite motif protein 50; tripartite motif-containing 50; tripartite
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • His
    • Myc/DDK
    • Myc
    • DDK
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human TRIM50-2652H Recombinant Human TRIM50 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Mouse TRIM50-17379M Recombinant Mouse TRIM50 Protein Mammalian Cell His
    Mouse Trim50-6658M Recombinant Mouse Trim50 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Rat TRIM50-6280R Recombinant Rat TRIM50 Protein Mammalian Cell His

    trim50 involved in several pathways and played different roles in them. We selected most pathways trim50 participated on our site, such as Adaptive Immune System, Antigen processing: Ubiquitination &amp, Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with trim50 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adaptive Immune System KIF3A; NRG2A; NCR3LG1; KIF4A; CTSE; ASB8; UBE2E3; UBA5; AHCYL1; PVRL2L
    Antigen processing: Ubiquitination &amp ASB14; PJA2; CMTM2A; FBXO27; ATG7; RNF19B; UBE2V2; ASB7; RNF14; UFL1
    Proteasome degradation ASB7; BLMH; PJA2; UBE2V2; LRSAM1; RNF6; ASB9; ASB14; ASB8; LRR1
    Class I MHC mediated antigen processing &amp KLHL21; ASB13; ASB4; RNF182; SH3RF1; VPRBP; DZIP3; FBXO27; SEC24A; ASB14
    presentation ASB13; NPEPPS; RNF111; STUB1; DZIP3; WWP1; ASB6; UBE2F; SEC24A; RBCK1
    Immune System FBXO17; SLAMF6; VPRBP; NCKIPSD; ARIH1; PANX1B; IFIT8; PRLRB; UFL1; IFIT11

    trim50 has several biochemical functions, for example, UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity, coenzyme F420-0 gamma-glutamyl ligase activity, coenzyme F420-2 alpha-glutamyl ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by trim50 itself. We selected most functions trim50 had, and list some proteins which have the same functions with trim50. You can find most of the proteins on our site.

    Function Related Protein
    UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity MARCH5L; NEURL1B; RNF169; ARIH1L; RNF144AA; TRIM50; RNF149; MYLIPA; MGRN1A; ZNRF2B
    coenzyme F420-0 gamma-glutamyl ligase activity NEURL3; UBR1; MARCH9; ZNRF2B; MYLIPA; ARIH1L; RNF169; UBE2IB; MUL1A; MARCH11
    coenzyme F420-2 alpha-glutamyl ligase activity RNF144AA; MARCH6; RNF169; HECW2; ARIH1L; LTN1; RFWD2; MGRN1A; MYLIPB; RNF144AB
    ligase activity TRIM28; DTX3L; PIAS1; RNF25; RNF146; RNF31; RBBP6; UHRF1; PIAS2; PARK2
    metal ion binding TRIM35-1; RACGAP1; PVALB7; CYP2AA6; ERMP1; ENTPD8; CHN2; UBR1; RPS27.1; RASAL1
    protein binding ZDHHC13; SYCE2; FSTL1; SHKBP1; SEPT9; GLB1; TNFSF13B; PIK3CB; C6orf226; RAB21
    protein-glutamic acid ligase activity MYLIPB; ZNRF3; MARCH4; MARCH9; RNF144AA; DTX1; MYLIPA; RNF187; TRIM41; MARCH6
    protein-glycine ligase activity TRIM50; SHRPRBCK1R; MARCH11; MYLIPB; MYLIPA; NEURL3; SIAH2L; TMEM129; RC3H2; MARCH6
    protein-glycine ligase activity, elongating MARCH4; MYLIPB; NEURL1B; SIAH1A; G2E3; ARIH1L; RNF187; UBE2IB; ZNRF2B; ITCHA
    protein-glycine ligase activity, initiating MARCH6; ZNRF3; HERC2; RNF187; MYLIPB; MUL1A; NEURL1B; TTLL3; RC3H2; MARCH4
    ribosomal S6-glutamic acid ligase activity ZNRF2B; NEURL1B; MUL1A; UBR1; RNF187; TMEM129; G2E3; MARCH4; UBE2M; MARCH5L
    tubulin-glutamic acid ligase activity MARCH9; G2E3; RC3H2; UBE2IA; UBE2IB; ITCHA; TTLL1; MYLIPB; SIAH1A; RNF144AA
    tubulin-glycine ligase activity LTN1; RC3H2; MYLIPA; RNF187; ZNRF2B; FLR; UBR1; TMEM129; HERC2; SHRPRBCK1R
    zinc ion binding RPH3A; ZDHHC17; FTR43; SIAH2; TRIM65; SOD3A; PTER; TRIM43C; NANOS3; RNF26

    trim50 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with trim50 here. Most of them are supplied by our site. Hope this information will be useful for your research of trim50.

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