TRIM50

  • Official Full Name

    tripartite motif containing 50

  • Synonyms

    TRIM50;tripartite motif containing 50;TRIM50A, tripartite motif containing 50 , tripartite motif containing 50A;E3 ubiquitin-protein ligase TRIM50;FLJ32804;E3 ubiquitin ligase;tripartite motif protein 50;tripartite motif-containing 50;tripartite

Recombinant Proteins

  • Mouse
  • Rat
  • Human
  • Mammalian Cells
  • HEK293
  • E. coli
  • His
  • DDK
  • Myc
  • Avi
  • Fc
  • GST

    Involved Pathway

    TRIM50 involved in several pathways and played different roles in them. We selected most pathways TRIM50 participated on our site, such as Adaptive Immune System,Antigen processing: Ubiquitination &amp,Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIM50 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Antigen processing: Ubiquitination &amp KLHL21,UBE2E3,ATG7,UBE2F,NPEPPS,TRIM69,RBCK1,RNF34,ASB7,FBXO17
    Immune System SEC24A,KIF18A,BTR18,CTSLL,ERAP2,IFIT12,TAX1BP1B,RNF123,TIRAP,DEFB121
    presentation SPSB2,SH3RF1,ASB17,ASB11,RNF25,RNF138,ASB18,FBXO3,FBXO44,FCGR1B
    Class I MHC mediated antigen processing &amp FBXO27,RNF111,ASB4,UBA5,RNF220,RNF25,TRIM9,UBE2L6,UBR1,ASB6
    Proteasome degradation UBE2J2,LRSAM1,UCHL3,UBE2U,RNF123,TRAF7,FBXO44,UFL1,ATG7,ASB11
    Adaptive Immune System LILRB2,SPTBN2,LILRB1,TPP2,ASB7,SIGLEC5,CTSL2,IFI30,NRG4,OSBPL1A

    Protein Function

    TRIM50 has several biochemical functions, for example, UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity,coenzyme F420-0 gamma-glutamyl ligase activity,coenzyme F420-2 alpha-glutamyl ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIM50 itself. We selected most functions TRIM50 had, and list some proteins which have the same functions with TRIM50. You can find most of the proteins on our site.

    Function Related Protein
    UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity RNF187,NEURL1B,RNF144AA,UBR1,RNF169,NEURL3,LTN1,UBE2IB,MARCH4,MYLIPB
    ribosomal S6-glutamic acid ligase activity ARIH1L,UBE2M,UBE2IB,RAG1,MGRN1A,ZNRF3,RNF169,HECW2,DTX1,RNF144AB
    metal ion binding SOD3A,ZRSR2,ECE1,POGZA,ZFP474,EGR2B,ZNHIT1,ZNF497,SMAD7,GM5136
    protein-glycine ligase activity SIAH1A,ZNRF3,HECW2,RC3H2,SHRPRBCK1R,SIAH2L,MARCH9,ITCHA,MYLIPA,TTLL3
    coenzyme F420-2 alpha-glutamyl ligase activity MUL1A,NEURL1B,TRIM41,MGRN1A,RAG1,HERC2,TMEM129,RC3H2,RNF187,SIAH2L
    protein binding ANLN,S100A12,ZNF232,GSG2,USP12,KTN1,KLK4,RGL2,CACNG1,SYT2
    protein-glutamic acid ligase activity HECW2,MARCH11,MGRN1A,MARCH5L,MARCH4,NEURL3,MYLIPA,RAG1,UBE2IB,SIAH2L
    ligase activity CBLL1,RNF4,RNF20,UNKL,TRAIP,ZNRF2B,DTX1,KCNG4,RNF170,PIAS2
    protein-glycine ligase activity, initiating RNF144AB,MARCH4,ZNRF2B,MARCH5L,SIAH2L,RAG1,RC3H2,MYLIPB,LTN1,MUL1A

    Interacting Protein

    TRIM50 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIM50 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIM50.

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