TRIM50

  • Official Full Name

    tripartite motif containing 50

  • Synonyms

    TRIM50;tripartite motif containing 50;TRIM50A, tripartite motif containing 50 , tripartite motif containing 50A;E3 ubiquitin-protein ligase TRIM50;FLJ32804;E3 ubiquitin ligase;tripartite motif protein 50;tripartite motif-containing 50;tripartite

Recombinant Proteins

  • Mouse
  • Rat
  • Human
  • Mammalian Cells
  • HEK293
  • E. coli
  • His
  • DDK
  • Myc
  • Avi
  • Fc
  • GST

    Involved Pathway

    TRIM50 involved in several pathways and played different roles in them. We selected most pathways TRIM50 participated on our site, such as Adaptive Immune System,Antigen processing: Ubiquitination &amp,Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIM50 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Antigen processing: Ubiquitination &amp ASB18,KLHL20,TPP2,RNF182,ASB8,UBE2J2,UBR2,NPEPPS,WSB1,KLHL21
    Adaptive Immune System KIF20A,CLEC2D,GRAP2B,KIF5B,CTS7,NCR3LG1,SEC61B,DCTN6,DCTN3,BLK
    Class I MHC mediated antigen processing &amp TPP2,UBR1,STUB1,CYBA,UBE2E3,RNF182,RNF6,PJA2,RNF19B,HECTD3
    presentation ASB14,CMTM2A,VPRBP,RNF138,RNF6,ASB9,GAN,PJA2,RNF41,LTN1
    Proteasome degradation UBE2U,RNF34,FBXO17,TRAF7,RNF25,ASB13,RNF19B,ASB8,ASB9,RNF144B
    Immune System IFIT11,PJA2,C1rb,KIF26A,CD300A,SPSB1,AP1G1,IFIT12,CLEC2D,ACTR2B

    Protein Function

    TRIM50 has several biochemical functions, for example, UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity,coenzyme F420-0 gamma-glutamyl ligase activity,coenzyme F420-2 alpha-glutamyl ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIM50 itself. We selected most functions TRIM50 had, and list some proteins which have the same functions with TRIM50. You can find most of the proteins on our site.

    Function Related Protein
    tubulin-glutamic acid ligase activity SIAH2L,MYLIPA,RC3H2,HERC2,RNF187,UBE2IA,RNF144AB,RNF144AA,ZNRF3,RNF169
    protein-glutamic acid ligase activity RNF187,MARCH4,UBE2IA,LTN1,UBR1,DTX1,MUL1A,RAG1,ITCHA,RNF180
    ribosomal S6-glutamic acid ligase activity TRIM71,DTX1,MGRN1A,RNF149,HECW2,UBE2IA,MARCH5L,MARCH9,MUL1A,MARCH6
    tubulin-glycine ligase activity TRIM71,MARCH5L,RNF149,RNF187,MARCH6,MYLIPB,TMEM129,RAG1,LTN1,ARIH1L
    zinc ion binding NR4A2B,PCGF5A,DNMT1,ZFML,ADAM9,OAS1,SRSF7,MMP15,APOBEC4,BPTF
    protein-glycine ligase activity, elongating RC3H2,SHRPRBCK1R,MARCH11,RFWD2,UBR1,HERC2,RNF144AB,MUL1A,TRIM71,ZNRF2B
    protein-glycine ligase activity, initiating TRIM71,UBE2IA,RFWD2,MYLIPA,UBE2IB,MYLIPB,MARCH5L,SIAH2L,LTN1,ZNRF3
    metal ion binding TGFBR1B,ATP1A1A.2,ZNF266,MT2,ARL3,GTSF1,CIZ1B,LHX6,TGM4,TNKS2
    coenzyme F420-0 gamma-glutamyl ligase activity RFWD2,UBR1,MYLIPA,RNF144AA,DTX1,TRIM71,ARIH1L,NEURL1B,G2E3,MARCH6

    Interacting Protein

    TRIM50 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIM50 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIM50.

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