TRIM50

  • Official Full Name

    tripartite motif containing 50

  • Synonyms

    TRIM50;tripartite motif containing 50;TRIM50A, tripartite motif containing 50 , tripartite motif containing 50A;E3 ubiquitin-protein ligase TRIM50;FLJ32804;E3 ubiquitin ligase;tripartite motif protein 50;tripartite motif-containing 50;tripartite

Recombinant Proteins

  • Mouse
  • Rat
  • Human
  • Mammalian Cells
  • HEK293
  • E. coli
  • His
  • DDK
  • Myc
  • Avi
  • Fc
  • GST

    Involved Pathway

    TRIM50 involved in several pathways and played different roles in them. We selected most pathways TRIM50 participated on our site, such as Adaptive Immune System,Antigen processing: Ubiquitination &amp,Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIM50 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Proteasome degradation LTN1,STUB1,SPSB4,ASB2,MKRN1,UBE2L6,SH3RF1,TRIM69,ASB7,UFL1
    Antigen processing: Ubiquitination &amp KLHL20,ASB7,RNF34,SPSB2,SPSB1,TRAF7,FBXO27,VPRBP,LRSAM1,TPP2
    Adaptive Immune System UBE2U,AP1S3A,LRR1,MICA,AP1B1,TRIM41,KIF20A,CD300LH,ACTR1A,FGFR1B
    Class I MHC mediated antigen processing &amp TRIM9,UBE2E3,TRIM11,RNF123,FBXO3,ASB4,PJA2,ASB13,GAN,SPSB4
    Immune System TRIM22,IgG3,DEFB121,IFIT10,TRIM48,CD300LD,RACGAP1,CTSLL,KLRB1B,PELI3
    presentation ASB14,CYBA,TRIM63,ERAP1,TRIM39,LTN1,FBXO3,ASB7,KLHL20,ASB13

    Protein Function

    TRIM50 has several biochemical functions, for example, UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity,coenzyme F420-0 gamma-glutamyl ligase activity,coenzyme F420-2 alpha-glutamyl ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIM50 itself. We selected most functions TRIM50 had, and list some proteins which have the same functions with TRIM50. You can find most of the proteins on our site.

    Function Related Protein
    protein-glutamic acid ligase activity HECW2,UBR1,ZNRF2B,DTX1,HERC2,G2E3,MARCH6,NEURL1B,ARIH1L,TRIM41
    coenzyme F420-0 gamma-glutamyl ligase activity ARIH1L,MUL1A,ITCHA,HERC2,MARCH6,UBE2IB,NEURL3,SHRPRBCK1R,UBR1,SIAH1A
    coenzyme F420-2 alpha-glutamyl ligase activity TMEM129,SHRPRBCK1R,G2E3,RNF180,MARCH6,RNF149,MUL1A,NEURL3,RNF169,TRIM41
    protein binding PRMT5,MPHOSPH8,ITGA6,RPL30,PPP1R2P3,CBS,LRP2BP,GDF7,SRGN,NEIL2
    ribosomal S6-glutamic acid ligase activity MUL1A,SHRPRBCK1R,RNF169,RNF187,NEURL1B,UBR1,ARIH1L,MARCH5L,RC3H2,RNF144AB
    UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity RNF144AA,RFWD2,LTN1,SIAH2L,MYLIPB,DTX1,SIAH1A,MARCH9,RNF180,UBE2IA
    ligase activity RNF144AA,RNF169,NSMCE2,BTRC,TNFAIP3,HECTD2,RNF38,MID2,RNF133,UFL1
    tubulin-glutamic acid ligase activity MARCH11,UBR1,TRIM41,G2E3,RNF144AA,RNF149,UBE2IA,MYLIPA,RNF144AB,RC3H2
    metal ion binding OASL2,ZNRF3,ZNF705A,MT1HL1,PAPL,ACAP1,ZNF580,ZNF784,BCO2,KLF7A

    Interacting Protein

    TRIM50 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIM50 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIM50.

    Resources

    References

    Reviews

    Write a review

    Q&As

    Ask a question

    Ask a Question for All TRIM50 Products

    Required fields are marked with *

    My Review for All TRIM50 Products

    Required fields are marked with *