TRIM50

  • Official Full Name

    tripartite motif containing 50

  • Synonyms

    TRIM50;tripartite motif containing 50;TRIM50A, tripartite motif containing 50 , tripartite motif containing 50A;E3 ubiquitin-protein ligase TRIM50;FLJ32804;E3 ubiquitin ligase;tripartite motif protein 50;tripartite motif-containing 50;tripartite

Recombinant Proteins

  • Mouse
  • Rat
  • Human
  • Mammalian Cells
  • HEK293
  • E. coli
  • His
  • DDK
  • Myc
  • Avi
  • Fc
  • GST

    Involved Pathway

    TRIM50 involved in several pathways and played different roles in them. We selected most pathways TRIM50 participated on our site, such as Adaptive Immune System,Antigen processing: Ubiquitination &amp,Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIM50 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    presentation RNF6,ASB8,ASB11,RNF19B,TRIM11,UBE2L6,ASB17,TPP2,BLMH,CMTM2A
    Adaptive Immune System KIF3C,CD207,NPEPPS,EGFR,MGC174155,CD200R4,LILRA1,KIF20A,TRIM39,MAP3K8
    Antigen processing: Ubiquitination &amp ATG7,LRR1,ASB8,FBXO3,RNF4,DZIP3,UFL1,UBE2L6,WWP1,DTX3L
    Proteasome degradation MKRN1,FBXO17,RNF123,ASB11,STUB1,RNF6,SH3RF1,ASB7,UCHL3,UBE2F
    Immune System DEFB119,UBE2E3,RNF135,TRIM46,DEFB125,RAP1GAP2,ASB13,BTR29,SOCS3A,PJA1
    Class I MHC mediated antigen processing &amp SEC24A,ASB17,TPP2,ATG7,RNF4,RNF6,FCGR1B,B2ML,RNF182,HUWE1

    Protein Function

    TRIM50 has several biochemical functions, for example, UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity,coenzyme F420-0 gamma-glutamyl ligase activity,coenzyme F420-2 alpha-glutamyl ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIM50 itself. We selected most functions TRIM50 had, and list some proteins which have the same functions with TRIM50. You can find most of the proteins on our site.

    Function Related Protein
    zinc ion binding ISL1L,FUS,RAG1,LMO2,TRIM11,CPM,MICALL2A,ZACN,NRAP,APOBEC3H
    coenzyme F420-0 gamma-glutamyl ligase activity SHRPRBCK1R,RNF169,RNF149,ARIH1L,DTX1,ZNRF3,MARCH4,SIAH1A,MUL1A,RNF144AB
    ribosomal S6-glutamic acid ligase activity RNF144AB,HECW2,MYLIPA,ZNRF2B,RNF144AA,MARCH11,TRIM71,RAG1,SIAH1A,DTX1
    protein-glycine ligase activity, elongating ZNRF2B,MGRN1A,TRIM41,DTX1,RC3H2,RNF169,LTN1,MYLIPA,MARCH9,NEURL1B
    metal ion binding MOB4,ZNF680,DDR1,TGM2B,ZNF582,ZNF653,LNX2A,ROCK2B,BA1,TPH1A
    UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity RNF144AA,SIAH2L,MARCH4,NEURL1B,RNF180,SHRPRBCK1R,UBE2IB,MUL1A,RNF169,ZNRF3
    tubulin-glutamic acid ligase activity ITCHA,MARCH6,RAG1,HECW2,RNF180,SHRPRBCK1R,LTN1,RNF187,ARIH1L,MARCH4
    protein-glycine ligase activity MARCH11,SHRPRBCK1R,TMEM129,MYLIPB,SIAH2L,RNF187,MUL1A,ZNRF3,G2E3,HECW2
    coenzyme F420-2 alpha-glutamyl ligase activity SIAH1A,MYLIPA,TMEM129,RFWD2,UBR1,TRIM71,G2E3,RNF169,RNF144AB,UBE2IA

    Interacting Protein

    TRIM50 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIM50 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIM50.

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