TRIM50

  • Official Full Name

    tripartite motif containing 50

  • Synonyms

    TRIM50;tripartite motif containing 50;TRIM50A, tripartite motif containing 50 , tripartite motif containing 50A;E3 ubiquitin-protein ligase TRIM50;FLJ32804;E3 ubiquitin ligase;tripartite motif protein 50;tripartite motif-containing 50;tripartite

Recombinant Proteins

  • Mouse
  • Rat
  • Human
  • Mammalian Cells
  • HEK293
  • E. coli
  • His
  • DDK
  • Myc
  • Avi
  • Fc
  • GST

    Involved Pathway

    TRIM50 involved in several pathways and played different roles in them. We selected most pathways TRIM50 participated on our site, such as Adaptive Immune System,Antigen processing: Ubiquitination &amp,Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIM50 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adaptive Immune System TPP2,FGF8B,AP1S1,RNF34,CTSO,LAIR1,KLB,GM11711,KIF2A,MAP3K8
    Proteasome degradation RNF138,MKRN1,RNF25,UBE2J2,RNF34,RNF182,ASB9,TPP2,RNF4,RNF41
    presentation UBE2U,SEC24A,RNF144B,RNF138,UBE2V2,RBCK1,ASB2,ASB13,LRSAM1,ATG7
    Immune System DEFB116,PANX1A,POLR3F,ADAR,PELI2,POLR3GLA,DUSP3,CTSE,UBE2U,DEFA3
    Class I MHC mediated antigen processing &amp GAN,SPSB2,TRIM11,UBA5,NPEPPS,ASB13,CTSL1,FCGR1B,UBR2,UBE2F
    Antigen processing: Ubiquitination &amp DTX3L,TPP2,UBE2J2,RNF182,RNF34,UBR2,UBE2L6,ASB11,UBE2U,TRIM11

    Protein Function

    TRIM50 has several biochemical functions, for example, UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity,coenzyme F420-0 gamma-glutamyl ligase activity,coenzyme F420-2 alpha-glutamyl ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIM50 itself. We selected most functions TRIM50 had, and list some proteins which have the same functions with TRIM50. You can find most of the proteins on our site.

    Function Related Protein
    tubulin-glycine ligase activity RNF149,NEURL1B,MARCH4,ITCHA,MARCH11,MYLIPB,MUL1A,RNF187,RNF144AB,RFWD2
    protein binding VPS33A,HMOX1,GFOD1,UBASH3A,DRAM1,C7orf53,FAM92A,SAP30L,TNS1,EPC1
    tubulin-glutamic acid ligase activity MARCH6,RNF144AA,NEURL3,ZNRF3,MYLIPB,UBE2IA,RNF180,ARIH1L,RAG1,RC3H2
    protein-glycine ligase activity, elongating SHRPRBCK1R,G2E3,TRIM41,UBE2IB,MYLIPA,NEURL3,MARCH5L,SIAH2L,NEURL1B,UBR1
    UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity SHRPRBCK1R,RFWD2,DTX1,UBE2IA,MARCH6,NEURL1B,MARCH11,UBR1,NEURL3,MYLIPB
    coenzyme F420-0 gamma-glutamyl ligase activity MGRN1A,MARCH5L,SIAH2L,HECW2,RFWD2,NEURL3,TRIM41,LTN1,TRIM71,MARCH4
    zinc ion binding LMO4A,CPA5,MICALL2,MSRB1,MMP14B,ADAM19,ADAMTS18,NR1I2,SUV39H2,Car9
    metal ion binding TYRP1B,STEAP2,PGGT1B,GTSF1,ZNF333,IKZF3,ZFP593,TAX1BP1B,ZNF227,NUDT8
    protein-glycine ligase activity LTN1,TRIM71,HECW2,SHRPRBCK1R,RNF180,UBE2IA,ZNRF2B,ITCHA,MYLIPA,TRIM41

    Interacting Protein

    TRIM50 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIM50 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIM50.

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