TRIM50

  • Official Full Name

    tripartite motif containing 50

  • Synonyms

    TRIM50;tripartite motif containing 50;TRIM50A, tripartite motif containing 50 , tripartite motif containing 50A;E3 ubiquitin-protein ligase TRIM50;FLJ32804;E3 ubiquitin ligase;tripartite motif protein 50;tripartite motif-containing 50;tripartite

Recombinant Proteins

  • Mouse
  • Rat
  • Human
  • Mammalian Cells
  • HEK293
  • E. coli
  • His
  • DDK
  • Myc
  • Avi
  • Fc
  • GST

    Involved Pathway

    TRIM50 involved in several pathways and played different roles in them. We selected most pathways TRIM50 participated on our site, such as Adaptive Immune System,Antigen processing: Ubiquitination &amp,Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIM50 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Proteasome degradation RBCK1,ATG7,ASB8,RNF6,ASB17,GAN,RNF4,BLMH,PJA2,TRIM39
    Class I MHC mediated antigen processing &amp ASB18,CMTM2A,SEC24A,RNF138,KLHL21,RNF41,CD207,RBCK1,WSB1,ASB9
    presentation UBE2F,CTSL2,RNF4,SEC23A,UBE2V2,ASB18,TRIM69,ASB3,TRIM11,KLHL21
    Immune System MGC174152,LILRA2,POLR3C,B2ML,LRR1,MAP3K8,DEFB4A,GRAP2A,CSHL1,DYNLL2
    Antigen processing: Ubiquitination &amp ASB8,ASB4,UBE2J2,CMTM2A,RNF138,ASB11,UBE2F,FBXO17,RNF4,UBE2V1
    Adaptive Immune System AGO3,ITGB1B.1,AHCYL1,LILRB3,CD300LB,LAIR2,FRS2,MAPKAP1,CD300LF,AP2M1

    Protein Function

    TRIM50 has several biochemical functions, for example, UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity,coenzyme F420-0 gamma-glutamyl ligase activity,coenzyme F420-2 alpha-glutamyl ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIM50 itself. We selected most functions TRIM50 had, and list some proteins which have the same functions with TRIM50. You can find most of the proteins on our site.

    Function Related Protein
    protein-glycine ligase activity, elongating HECW2,RC3H2,RAG1,NEURL1B,UBE2IA,RNF144AB,SIAH1A,RNF187,ZNRF3,TRIM41
    protein-glycine ligase activity RNF144AB,LTN1,RNF180,ITCHA,MGRN1A,DTX1,RNF187,MYLIPB,SIAH2L,RC3H2
    UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity MYLIPA,MARCH9,MYLIPB,MARCH11,RNF180,ZNRF3,MARCH5L,RNF144AA,RNF187,DTX1
    tubulin-glutamic acid ligase activity RNF149,RNF144AA,RNF187,MYLIPB,TRIM41,TRIM71,RFWD2,MARCH4,HECW2,MYLIPA
    protein binding GGA1,RTN4RL2B,KLHDC3,DZIP3,LPL,TUSC2,KIR2DL4,SIAH1A,CRTC2,ACVR1B
    ligase activity TRIM71,LIPT2,RNF133,HUWE1,MKRN1,SIAH2L,DTX2,CBLC,SIAH1,TRIM41
    protein-glycine ligase activity, initiating ITCHA,MYLIPA,HECW2,ZNRF2B,SIAH1A,SIAH2L,G2E3,NEURL1B,RNF149,MARCH4
    ribosomal S6-glutamic acid ligase activity SHRPRBCK1R,MYLIPB,RNF169,ZNRF2B,RC3H2,NEURL1B,MGRN1A,ITCHA,UBR1,RAG1
    coenzyme F420-2 alpha-glutamyl ligase activity RAG1,HERC2,HECW2,RNF187,MARCH9,TRIM71,RNF180,SIAH2L,G2E3,MUL1A

    Interacting Protein

    TRIM50 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIM50 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIM50.

    Resources

    References

    Reviews

    Write a review

    Q&As

    Ask a question

    Ask a Question for All TRIM50 Products

    Required fields are marked with *

    My Review for All TRIM50 Products

    Required fields are marked with *