TRIM50

  • Official Full Name

    tripartite motif containing 50

  • Synonyms

    TRIM50;tripartite motif containing 50;TRIM50A, tripartite motif containing 50 , tripartite motif containing 50A;E3 ubiquitin-protein ligase TRIM50;FLJ32804;E3 ubiquitin ligase;tripartite motif protein 50;tripartite motif-containing 50;tripartite

Recombinant Proteins

  • Mouse
  • Rat
  • Human
  • Mammalian Cells
  • HEK293
  • E. coli
  • His
  • DDK
  • Myc
  • Avi
  • Fc
  • GST

    Involved Pathway

    TRIM50 involved in several pathways and played different roles in them. We selected most pathways TRIM50 participated on our site, such as Adaptive Immune System,Antigen processing: Ubiquitination &amp,Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIM50 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Proteasome degradation ASB6,RNF182,TRIM9,RNF6,PJA1,SPSB1,UBE2E3,SPSB2,LRRC41,ASB17
    Immune System SEC61B,TAX1BP1,CTSK,AF251705,CD300LF,LILRB1,HBL3,LGALS3,BST2,KIF3B
    Antigen processing: Ubiquitination &amp DTX3L,RNF138,ASB18,ATG7,RNF144B,ASB4,NPEPPS,ASB7,UBE2V1,ASB2
    Adaptive Immune System RAET1E,PJA1,CD300A,AMICA1,TRAF7,ASB4,CD207,TRIM69,AGO1,UBE2F
    Class I MHC mediated antigen processing &amp LTN1,KLHL21,ASB9,ASB10,ASB2,KLHL20,LRR1,ERAP2,SEC24A,UBE2J2
    presentation RNF4,FBXO27,TRIM69,NPEPPS,TRAF7,TRIM9,RNF14,MKRN1,UBE2F,ASB10

    Protein Function

    TRIM50 has several biochemical functions, for example, UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity,coenzyme F420-0 gamma-glutamyl ligase activity,coenzyme F420-2 alpha-glutamyl ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIM50 itself. We selected most functions TRIM50 had, and list some proteins which have the same functions with TRIM50. You can find most of the proteins on our site.

    Function Related Protein
    zinc ion binding UBR1,PHF23,OTUD7A,GFI1AA,TGFB1I1,FHL2B,NEIL3,TRIM35-20,PDLIM3B,TRIP6
    protein-glycine ligase activity, initiating LTN1,RNF180,NEURL3,NEURL1B,TRIM41,ARIH1L,ZNRF3,DTX1,RNF144AB,RC3H2
    protein-glutamic acid ligase activity ITCHA,RC3H2,RNF180,HERC2,RNF144AA,ARIH1L,NEURL3,UBE2IA,ZNRF3,NEURL1B
    ribosomal S6-glutamic acid ligase activity RNF180,MYLIPB,UBR1,ZNRF3,UBE2M,MARCH6,TMEM129,MARCH4,RAG1,MARCH9
    metal ion binding PDE1A,MAT2A,NEK7,LONRF1L,LHX1B,CALUA,RNF207,MARCH11,UNK,POLM
    ligase activity TRIM9,MGRN1,TRAIP,RNF38,RNF5,RBCK1,ITCHA,RNF138,UBE4B,LIPT2
    UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity ARIH1L,RC3H2,UBR1,MUL1A,RNF149,HECW2,RNF144AB,RAG1,MYLIPB,MYLIPA
    protein-glycine ligase activity RNF187,RNF144AA,MARCH6,SHRPRBCK1R,NEURL1B,ZNRF2B,TTLL3,SIAH1A,ITCHA,MARCH11
    tubulin-glutamic acid ligase activity HECW2,ZNRF3,MUL1A,RAG1,LTN1,TRIM41,MARCH5L,TTLL1,RC3H2,RFWD2

    Interacting Protein

    TRIM50 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIM50 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIM50.

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