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TRIM50

  • Official Full Name

    tripartite motif containing 50

  • Synonyms

    TRIM50; tripartite motif containing 50; TRIM50A, tripartite motif containing 50 , tripartite motif containing 50A; E3 ubiquitin-protein ligase TRIM50; FLJ32804; E3 ubiquitin ligase; tripartite motif protein 50; tripartite motif-containing 50; tripartite;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • HEK293
  • HEK293T
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TRIM50-2652H Recombinant Human TRIM50 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Mouse TRIM50-17379M Recombinant Mouse TRIM50 Protein Mammalian Cell His
Mouse Trim50-6658M Recombinant Mouse Trim50 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse TRIM50-9612M Recombinant Mouse TRIM50 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse TRIM50-9612M-B Recombinant Mouse TRIM50 Protein Pre-coupled Magnetic Beads HEK293
Rat TRIM50-6280R Recombinant Rat TRIM50 Protein Mammalian Cell His
Rat TRIM50-5937R Recombinant Rat TRIM50 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat TRIM50-5937R-B Recombinant Rat TRIM50 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein

TRIM50 involved in several pathways and played different roles in them. We selected most pathways TRIM50 participated on our site, such as Adaptive Immune System, Antigen processing: Ubiquitination &amp, Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIM50 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Adaptive Immune SystemCD300LD;UBE2L6;PDPK1A;SEC61B;KLRB1B;RNF138;LAIR2;KIR2DS2;KIF5A
Antigen processing: Ubiquitination &ampKLHL20;UBE2V2;ASB18;WWP1;TRIM50;FBXO27;RNF138;ASB8;LRR1
Proteasome degradationSPSB2;LRRC41;UBE2F;RNF220;KLHL20;SH3RF1;ASB10;ASB14;ATG7
Class I MHC mediated antigen processing &ampTRAF7;ASB4;RNF220;ASB2;CTSL1;UFL1;ASB8;STUB1;DTX3L
presentationSEC24A;RNF144B;PJA2;LRRC41;ASB13;UBR2;WSB1;ARIH2;SH3RF1
Immune SystemDHX9;SIGLEC5;TRIM17;TRIM62;TRIM2;DEFB116;ASB18;RNF6;CSH1

TRIM50 has several biochemical functions, for example, UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity, coenzyme F420-0 gamma-glutamyl ligase activity, coenzyme F420-2 alpha-glutamyl ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIM50 itself. We selected most functions TRIM50 had, and list some proteins which have the same functions with TRIM50. You can find most of the proteins on our site.

Function Related Protein
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activityRNF187;SIAH2L;G2E3;DTX1;LTN1;UBR1;TMEM129;SIAH1A;ITCHA
coenzyme F420-0 gamma-glutamyl ligase activityMYLIPB;MARCH6;RNF187;MARCH4;TRIM50;MYLIPA;DTX1;MARCH5L;TRIM41
coenzyme F420-2 alpha-glutamyl ligase activityTMEM129;MYLIPB;RNF187;HECW2;UBE2IA;UBE2IB;MARCH9;RNF169;ITCHA
ligase activitySMURF2;RNF34;RNF144B;G2E3;COP1;HERC4;PIAS3;RNF43;LNX1
metal ion bindingPNLIP;ZNF446;SMYD2A;ZNF200;ZNF395B;PRDM9;CYP2X9;ICN;GMPR2
protein bindingCXXC5;C12orf40;RPS25;ACTN1;ZNF649;HTR1A;SRSF11;NXF3;PRPS1
protein-glutamic acid ligase activityHECW2;RNF180;RFWD2;ZNRF3;TMEM129;TRIM71;HERC2;UBE2IB;SHRPRBCK1R
protein-glycine ligase activityDTX1;HECW2;MARCH4;RNF144AA;MARCH9;HERC2;ZNRF2B;ARIH1L;MGRN1A
protein-glycine ligase activity, elongatingDTX1;MARCH4;MGRN1A;LTN1;MARCH6;MARCH9;SIAH2L;ARIH1L;UBE2IA
protein-glycine ligase activity, initiatingZNRF2B;MGRN1A;MARCH4;MYLIPA;MARCH5L;MUL1A;TRIM50;RNF169;MYLIPB
ribosomal S6-glutamic acid ligase activityUBR1;MUL1A;RNF144AB;TRIM71;MARCH11;MARCH6;G2E3;MYLIPA;LTN1
tubulin-glutamic acid ligase activityTRIM71;TRIM41;MUL1A;NEURL1B;RAG1;MARCH9;MYLIPB;MGRN1A;TTLL1
tubulin-glycine ligase activitySIAH2L;MGRN1A;MUL1A;RNF187;SHRPRBCK1R;ITCHA;MYLIPB;DTX1;NEURL3
zinc ion bindingZFP330;FBXO11;WBP2NL;NRAP;YY1;ZMYM5;ADH5;SNCA;FHL2B

TRIM50 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIM50 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIM50.

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