TRIM50

  • Official Full Name

    tripartite motif containing 50

  • Synonyms

    TRIM50;tripartite motif containing 50;TRIM50A, tripartite motif containing 50 , tripartite motif containing 50A;E3 ubiquitin-protein ligase TRIM50;FLJ32804;E3 ubiquitin ligase;tripartite motif protein 50;tripartite motif-containing 50;tripartite

Recombinant Proteins

  • Mouse
  • Rat
  • Human
  • Mammalian Cells
  • HEK293
  • E. coli
  • His
  • DDK
  • Myc
  • Avi
  • Fc
  • GST

    Involved Pathway

    TRIM50 involved in several pathways and played different roles in them. We selected most pathways TRIM50 participated on our site, such as Adaptive Immune System,Antigen processing: Ubiquitination &amp,Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIM50 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Class I MHC mediated antigen processing &amp ASB7,ASB14,CTSL2,RNF6,KLHL21,RNF4,DTX3L,WSB1,ASB3,LRSAM1
    Immune System LAIR2,MX2,CD226,SEC61B,RNF25,RNF19B,TREML1,ACTR1B,DEFB104A,TRIM46
    Antigen processing: Ubiquitination &amp TRIM41,DTX3L,ASB3,UBE2E3,UBE2F,SPSB2,TPP2,UBR1,UBE2V2,FBXO3
    Proteasome degradation UCHL3,ASB3,UBE2F,IWS1,PJA2,ASB13,ASB14,TPP2,FBXO27,UBE2E3
    Adaptive Immune System CTSL2,UBE2V2,NA,CTSO,DTX3L,TRIM63,CD300LF,RNF138,ASB4,RNF14
    presentation TRIM39,RNF4,RNF111,RNF14,ASB10,PJA1,TRIM41,FBXO17,UBA5,CTSL2

    Protein Function

    TRIM50 has several biochemical functions, for example, UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity,coenzyme F420-0 gamma-glutamyl ligase activity,coenzyme F420-2 alpha-glutamyl ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIM50 itself. We selected most functions TRIM50 had, and list some proteins which have the same functions with TRIM50. You can find most of the proteins on our site.

    Function Related Protein
    tubulin-glycine ligase activity RNF144AB,MARCH9,HERC2,HECW2,MARCH5L,MARCH11,MYLIPB,ARIH1L,ZNRF3,ITCHA
    zinc ion binding PEX10,C6AST3,ZDHHC18B,S100A8,RNF39,CRIP3,BRF1B,DUSP12,PRICKLE1,RPS29
    protein binding APC,PTPN14,MRPL53,WDR74,MLF1,ASB7,Trf,ARL14,PER2,DKK1
    ligase activity RTCB,MKRN3,ARIH1,PELI3,RCHY1,HECTD3,RNF144B,UBR7,HUWE1,NAPRT1
    coenzyme F420-2 alpha-glutamyl ligase activity MARCH9,RC3H2,HECW2,NEURL1B,ZNRF2B,MARCH11,TMEM129,NEURL3,RNF180,RNF144AA
    protein-glycine ligase activity, initiating RNF144AB,NEURL3,MARCH4,MARCH5L,TRIM71,DTX1,TMEM129,RNF169,UBR1,NEURL1B
    tubulin-glutamic acid ligase activity ARIH1L,G2E3,RNF169,MUL1A,DTX1,UBE2IB,RFWD2,HECW2,RAG1,MGRN1A
    UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity UBE2IA,RNF187,MGRN1A,TRIM41,SHRPRBCK1R,RNF144AA,ZNRF3,MYLIPA,G2E3,ZNRF2B
    protein-glycine ligase activity, elongating SIAH2L,UBE2IA,UBE2IB,NEURL1B,ZNRF3,MYLIPB,TRIM41,RNF180,MGRN1A,RNF169

    Interacting Protein

    TRIM50 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIM50 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIM50.

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