TRIM50

  • Official Full Name

    tripartite motif containing 50

  • Synonyms

    TRIM50;tripartite motif containing 50;TRIM50A, tripartite motif containing 50 , tripartite motif containing 50A;E3 ubiquitin-protein ligase TRIM50;FLJ32804;E3 ubiquitin ligase;tripartite motif protein 50;tripartite motif-containing 50;tripartite

Recombinant Proteins

  • Mouse
  • Rat
  • Human
  • Mammalian Cells
  • HEK293
  • E. coli
  • His
  • DDK
  • Myc
  • Avi
  • Fc
  • GST

    Involved Pathway

    TRIM50 involved in several pathways and played different roles in them. We selected most pathways TRIM50 participated on our site, such as Adaptive Immune System,Antigen processing: Ubiquitination &amp,Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIM50 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Proteasome degradation RNF19B,TRIM41,RNF220,UBR1,ASB9,ASB14,STUB1,WSB1,BLMH,SH3RF1
    Class I MHC mediated antigen processing &amp CYBA,ASB17,MKRN1,PJA2,TRIM39,SH3RF1,B2ML,ASB4,UBE2V1,DZIP3
    Antigen processing: Ubiquitination &amp RNF138,FBXO27,RNF4,KLHL21,CMTM2A,RNF144B,TRIM9,LRRC41,UBR2,UBE2L6
    Adaptive Immune System DCTN2,KLB,CD226,SPTBN2,RNF6,CTSH,KIF3B,SH2D1B,ERAP1,TRIM63
    Immune System LRSAM1,CLEC2G,RNF182,CD200R1,HBL3,DEFB4A,LILRB2,SIGLEC12,DYNC1H1,TRIM63
    presentation RNF14,SPSB1,ASB9,PJA2,FBXO17,FCGR1B,RNF144B,ARIH2,LRSAM1,UBE2L6

    Protein Function

    TRIM50 has several biochemical functions, for example, UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity,coenzyme F420-0 gamma-glutamyl ligase activity,coenzyme F420-2 alpha-glutamyl ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIM50 itself. We selected most functions TRIM50 had, and list some proteins which have the same functions with TRIM50. You can find most of the proteins on our site.

    Function Related Protein
    tubulin-glycine ligase activity RFWD2,RNF149,RNF144AB,ZNRF2B,RC3H2,LTN1,SIAH1A,TRIM71,MARCH5L,UBE2IB
    tubulin-glutamic acid ligase activity SIAH2L,HERC2,UBE2IA,ZNRF2B,TMEM129,MARCH11,MUL1A,RNF187,TRIM41,UBE2IB
    protein-glycine ligase activity, elongating MARCH6,RNF180,HECW2,RC3H2,MUL1A,LTN1,MARCH9,NEURL3,ZNRF2B,RAG1
    protein-glutamic acid ligase activity MARCH4,SHRPRBCK1R,HERC2,RFWD2,MARCH6,RAG1,TRIM41,RNF144AB,TMEM129,RC3H2
    ribosomal S6-glutamic acid ligase activity TRIM41,SHRPRBCK1R,RNF149,RNF187,MARCH4,UBE2M,TRIM71,MYLIPB,RFWD2,HERC2
    metal ion binding ICN,ZNF764,ZNF576,EBF4,KLF18,SOBPB,ZNF526,ZNF350,AOX3L1,ZHX2
    protein-glycine ligase activity RNF169,UBE2IB,MGRN1A,TRIM71,SIAH2L,SIAH1A,HECW2,RNF144AB,MARCH4,DTX1
    protein-glycine ligase activity, initiating UBR1,RAG1,RNF169,MYLIPB,SIAH2L,MUL1A,TRIM71,G2E3,MARCH5L,RFWD2
    zinc ion binding RBM5,MMP26,PDZRN4,L3MBTL1,PXN,ZFP330,VAT1,RNF175,BMP1A,RNF133

    Interacting Protein

    TRIM50 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIM50 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIM50.

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