| Official Full Name | tripartite motif containing 50 |
| Synonyms | TRIM50; tripartite motif containing 50; TRIM50A, tripartite motif containing 50 , tripartite motif containing 50A; E3 ubiquitin-protein ligase TRIM50; FLJ32804; E3 ubiquitin ligase; tripartite motif protein 50; tripartite motif-containing 50; tripartite |
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|
trim50 involved in several pathways and played different roles in them. We selected most pathways trim50 participated on our site, such as Adaptive Immune System, Antigen processing: Ubiquitination &, Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with trim50 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Adaptive Immune System | CLEC2H; RNF6; RNF14; UBE2U; IGKC; SPSB4; UBE2E3; MGC174155; CSK; DYNC1I2 |
| Antigen processing: Ubiquitination & | UBE2V2; UBA5; FBXO17; ASB18; ASB2; SPSB2; UBE2V1; LRR1; RNF41; FBXO44 |
| Proteasome degradation | KLHL21; GAN; UBE2L6; UBE2F; RNF220; RNF14; RNF123; LRSAM1; VPRBP; FBXO3 |
| Class I MHC mediated antigen processing & | CTSS; RNF123; RNF144B; SEC61B; ARIH2; PJA2; SEC23A; ASB14; STUB1; KLHL21 |
| presentation | ASB8; CTSS; LTN1; SH3RF1; CTSL1; UBE2V2; TRIM41; SPSB1; ASB9; TRIM63 |
| Immune System | CSHL1; IFIT10; CYLD; GRAP2A; DEFB129; LILRA3; TRIM41; IRAK3; RNF144B; RNF25 |
trim50 has several biochemical functions, for example, UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity, coenzyme F420-0 gamma-glutamyl ligase activity, coenzyme F420-2 alpha-glutamyl ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by trim50 itself. We selected most functions trim50 had, and list some proteins which have the same functions with trim50. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity | TRIM50; RNF187; G2E3; RAG1; ARIH1L; ZNRF3; UBE2IA; SHRPRBCK1R; RNF144AA; RNF169 |
| coenzyme F420-0 gamma-glutamyl ligase activity | SIAH1A; ZNRF3; RNF180; LTN1; ITCHA; ZNRF2B; RNF187; UBR1; RNF169; NEURL3 |
| coenzyme F420-2 alpha-glutamyl ligase activity | TRIM41; SHRPRBCK1R; MYLIPA; ZNRF2B; MARCH5L; MGRN1A; MUL1A; HECW2; RNF144AA; MARCH6 |
| ligase activity | TRIM8; HECW2; RNF152; FPGS; UBR2; RNF213; RNF111; TTLL6; TRAF6; C12orf51 |
| metal ion binding | GTPBP6; ZNF572; PDE6B; ZNF561; CYP2Y3; DCST1; ZIC6; ZBTB12; NMRK2; DMRTA2 |
| protein binding | C2orf88; ALG2; LDHD; KRTAP23-1; MED25; PDGFC; POU2F1; CBX7; BDKRB1; RAB39A |
| protein-glutamic acid ligase activity | NEURL1B; ITCHA; UBE2IB; SIAH2L; ARIH1L; MARCH9; RC3H2; NEURL3; RNF187; MARCH5L |
| protein-glycine ligase activity | TRIM71; MGRN1A; TTLL3; UBE2IA; UBE2IB; RNF149; MARCH4; RC3H2; ITCHA; RNF144AA |
| protein-glycine ligase activity, elongating | NEURL3; RNF149; RFWD2; TRIM50; ZNRF3; DTX1; UBR1; NEURL1B; RAG1; RC3H2 |
| protein-glycine ligase activity, initiating | UBR1; RAG1; LTN1; RNF144AB; MARCH5L; RNF187; ZNRF3; TMEM129; HECW2; RFWD2 |
| ribosomal S6-glutamic acid ligase activity | LTN1; TRIM41; TRIM50; UBE2M; RNF144AB; ZNRF3; MUL1A; G2E3; MARCH9; UBE2IB |
| tubulin-glutamic acid ligase activity | SHRPRBCK1R; UBE2IA; MARCH4; RAG1; MARCH6; TRIM50; RNF144AA; HERC2; MARCH11; MGRN1A |
| tubulin-glycine ligase activity | SHRPRBCK1R; SIAH2L; NEURL3; MYLIPB; RNF180; UBR1; MARCH6; RNF169; NEURL1B; RNF144AB |
| zinc ion binding | CLIP1; TRIM35-29; FHL2B; MLL5; ZDHHC8B; CAR6; RABGEF1L; ADAM17; DBF4B; ZMAT3 |
trim50 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with trim50 here. Most of them are supplied by our site. Hope this information will be useful for your research of trim50.
