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Official Full Name tripartite motif containing 50
Synonyms TRIM50; tripartite motif containing 50; TRIM50A, tripartite motif containing 50 , tripartite motif containing 50A; E3 ubiquitin-protein ligase TRIM50; FLJ32804; E3 ubiquitin ligase; tripartite motif protein 50; tripartite motif-containing 50; tripartite
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • Myc
    • DDK
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human TRIM50-2652H Recombinant Human TRIM50 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Mouse TRIM50-17379M Recombinant Mouse TRIM50 Protein Mammalian Cell His
    Rat TRIM50-6280R Recombinant Rat TRIM50 Protein Mammalian Cell His

    trim50 involved in several pathways and played different roles in them. We selected most pathways trim50 participated on our site, such as Adaptive Immune System, Antigen processing: Ubiquitination &amp, Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with trim50 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adaptive Immune System CLEC2H; RNF6; RNF14; UBE2U; IGKC; SPSB4; UBE2E3; MGC174155; CSK; DYNC1I2
    Antigen processing: Ubiquitination &amp UBE2V2; UBA5; FBXO17; ASB18; ASB2; SPSB2; UBE2V1; LRR1; RNF41; FBXO44
    Proteasome degradation KLHL21; GAN; UBE2L6; UBE2F; RNF220; RNF14; RNF123; LRSAM1; VPRBP; FBXO3
    Class I MHC mediated antigen processing &amp CTSS; RNF123; RNF144B; SEC61B; ARIH2; PJA2; SEC23A; ASB14; STUB1; KLHL21
    presentation ASB8; CTSS; LTN1; SH3RF1; CTSL1; UBE2V2; TRIM41; SPSB1; ASB9; TRIM63
    Immune System CSHL1; IFIT10; CYLD; GRAP2A; DEFB129; LILRA3; TRIM41; IRAK3; RNF144B; RNF25

    trim50 has several biochemical functions, for example, UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity, coenzyme F420-0 gamma-glutamyl ligase activity, coenzyme F420-2 alpha-glutamyl ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by trim50 itself. We selected most functions trim50 had, and list some proteins which have the same functions with trim50. You can find most of the proteins on our site.

    Function Related Protein
    UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity TRIM50; RNF187; G2E3; RAG1; ARIH1L; ZNRF3; UBE2IA; SHRPRBCK1R; RNF144AA; RNF169
    coenzyme F420-0 gamma-glutamyl ligase activity SIAH1A; ZNRF3; RNF180; LTN1; ITCHA; ZNRF2B; RNF187; UBR1; RNF169; NEURL3
    coenzyme F420-2 alpha-glutamyl ligase activity TRIM41; SHRPRBCK1R; MYLIPA; ZNRF2B; MARCH5L; MGRN1A; MUL1A; HECW2; RNF144AA; MARCH6
    ligase activity TRIM8; HECW2; RNF152; FPGS; UBR2; RNF213; RNF111; TTLL6; TRAF6; C12orf51
    metal ion binding GTPBP6; ZNF572; PDE6B; ZNF561; CYP2Y3; DCST1; ZIC6; ZBTB12; NMRK2; DMRTA2
    protein binding C2orf88; ALG2; LDHD; KRTAP23-1; MED25; PDGFC; POU2F1; CBX7; BDKRB1; RAB39A
    protein-glutamic acid ligase activity NEURL1B; ITCHA; UBE2IB; SIAH2L; ARIH1L; MARCH9; RC3H2; NEURL3; RNF187; MARCH5L
    protein-glycine ligase activity TRIM71; MGRN1A; TTLL3; UBE2IA; UBE2IB; RNF149; MARCH4; RC3H2; ITCHA; RNF144AA
    protein-glycine ligase activity, elongating NEURL3; RNF149; RFWD2; TRIM50; ZNRF3; DTX1; UBR1; NEURL1B; RAG1; RC3H2
    protein-glycine ligase activity, initiating UBR1; RAG1; LTN1; RNF144AB; MARCH5L; RNF187; ZNRF3; TMEM129; HECW2; RFWD2
    ribosomal S6-glutamic acid ligase activity LTN1; TRIM41; TRIM50; UBE2M; RNF144AB; ZNRF3; MUL1A; G2E3; MARCH9; UBE2IB
    tubulin-glutamic acid ligase activity SHRPRBCK1R; UBE2IA; MARCH4; RAG1; MARCH6; TRIM50; RNF144AA; HERC2; MARCH11; MGRN1A
    tubulin-glycine ligase activity SHRPRBCK1R; SIAH2L; NEURL3; MYLIPB; RNF180; UBR1; MARCH6; RNF169; NEURL1B; RNF144AB
    zinc ion binding CLIP1; TRIM35-29; FHL2B; MLL5; ZDHHC8B; CAR6; RABGEF1L; ADAM17; DBF4B; ZMAT3

    trim50 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with trim50 here. Most of them are supplied by our site. Hope this information will be useful for your research of trim50.

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