TRIM50

  • Official Full Name

    tripartite motif containing 50

  • Synonyms

    TRIM50;tripartite motif containing 50;TRIM50A, tripartite motif containing 50 , tripartite motif containing 50A;E3 ubiquitin-protein ligase TRIM50;FLJ32804;E3 ubiquitin ligase;tripartite motif protein 50;tripartite motif-containing 50;tripartite

Recombinant Proteins

  • Mouse
  • Rat
  • Human
  • Mammalian Cells
  • HEK293
  • E. coli
  • His
  • DDK
  • Myc
  • Avi
  • Fc
  • GST

    Involved Pathway

    TRIM50 involved in several pathways and played different roles in them. We selected most pathways TRIM50 participated on our site, such as Adaptive Immune System,Antigen processing: Ubiquitination &amp,Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIM50 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    presentation SPSB1,CTSS,TPP2,LRRC41,HUWE1,LRSAM1,ERAP1,DZIP3,FBXO44,UBE2J2
    Proteasome degradation UBE2V1,KLHL20,IWS1,ASB14,LRSAM1,LRR1,ATG7,TRIM69,ASB11,RNF144B
    Adaptive Immune System FRS2,CREB1B,KIF3A,ITPR2,CLEC2H,RNF6,CYBB,FBXO27,GM11711,SEC23A
    Class I MHC mediated antigen processing &amp LTN1,TRAF7,SEC61B,UBE2J2,DZIP3,RNF41,RNF220,ASB2,ASB9,ASB6
    Antigen processing: Ubiquitination &amp UBR1,ASB2,ASB6,ASB4,VPRBP,SPSB1,FBXO3,TRIM69,RNF144B,WWP1
    Immune System SIGLEC9,DTX3L,CD300LB,CASP4,EDARADD,KPNA4,RNF6,KLRG1,IFIT2,TRIM41

    Protein Function

    TRIM50 has several biochemical functions, for example, UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity,coenzyme F420-0 gamma-glutamyl ligase activity,coenzyme F420-2 alpha-glutamyl ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIM50 itself. We selected most functions TRIM50 had, and list some proteins which have the same functions with TRIM50. You can find most of the proteins on our site.

    Function Related Protein
    metal ion binding RFESD,ITGAL,NRP2A,CYP2C38,Scd2,RPS27L,WT1A,DZIP1L,PRUNE2,NUDT19
    protein-glycine ligase activity, elongating ZNRF3,RAG1,MYLIPA,MARCH6,UBE2IA,UBR1,SIAH2L,MARCH9,ARIH1L,RFWD2
    protein-glutamic acid ligase activity MARCH6,G2E3,UBE2IA,RNF187,HECW2,SHRPRBCK1R,UBR1,MYLIPB,RNF144AB,NEURL1B
    UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity TRIM41,RAG1,HECW2,RNF144AB,UBE2IA,SHRPRBCK1R,G2E3,MGRN1A,MYLIPA,MARCH4
    tubulin-glycine ligase activity ITCHA,FLR,LTN1,RAG1,TRIM41,RNF180,UBR1,MARCH4,MYLIPA,ZNRF2B
    protein binding PAX8,VDAC1,APLP1,ALK,APOBEC3H,MYRIP,RTN2,FGF7,UROD,MED23
    protein-glycine ligase activity, initiating G2E3,RC3H2,SIAH2L,SHRPRBCK1R,HERC2,RFWD2,RNF144AA,RNF169,ZNRF3,MARCH4
    tubulin-glutamic acid ligase activity MGRN1A,RFWD2,TRIM41,RNF187,MARCH9,RNF144AB,MARCH4,MARCH11,HECW2,LTN1
    ribosomal S6-glutamic acid ligase activity UBE2IB,RC3H2,NEURL3,MYLIPB,ZNRF3,RNF169,G2E3,MARCH6,DTX1,TRIM71

    Interacting Protein

    TRIM50 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIM50 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIM50.

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