TRIM50

  • Official Full Name

    tripartite motif containing 50

  • Synonyms

    TRIM50;tripartite motif containing 50;TRIM50A, tripartite motif containing 50 , tripartite motif containing 50A;E3 ubiquitin-protein ligase TRIM50;FLJ32804;E3 ubiquitin ligase;tripartite motif protein 50;tripartite motif-containing 50;tripartite

Recombinant Proteins

  • Mouse
  • Rat
  • Human
  • Mammalian Cells
  • HEK293
  • E. coli
  • His
  • DDK
  • Myc
  • Avi
  • Fc
  • GST

    Involved Pathway

    TRIM50 involved in several pathways and played different roles in them. We selected most pathways TRIM50 participated on our site, such as Adaptive Immune System,Antigen processing: Ubiquitination &amp,Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIM50 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    presentation RNF123,RNF6,CD207,SEC24A,TRIM11,RNF111,DZIP3,WSB1,UBE2V2,SPSB1
    Antigen processing: Ubiquitination &amp UBE2L6,PJA1,SPSB4,RNF19B,TRIM41,KLHL20,SPSB1,RNF138,RBCK1,ASB6
    Proteasome degradation NPEPPS,RNF19B,UBE2F,ASB7,SPSB4,ASB13,SPSB1,UBA5,RNF41,MKRN1
    Immune System RNF135,TNIP2,CTSO,EIF4G2A,STIM1B,SIGLEC7,PANX1A,CFHL1,ASB14,KIFAP3
    Class I MHC mediated antigen processing &amp ASB3,ASB8,RNF19B,ERAP2,LRRC41,CMTM2A,TRIM39,TRIM41,RNF138,RNF6
    Adaptive Immune System HBEGF,CTSS,CLEC2B,RNF182,CTSO,AP2M1,LTN1,RACGAP1,TPP2,AP2A1

    Protein Function

    TRIM50 has several biochemical functions, for example, UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity,coenzyme F420-0 gamma-glutamyl ligase activity,coenzyme F420-2 alpha-glutamyl ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIM50 itself. We selected most functions TRIM50 had, and list some proteins which have the same functions with TRIM50. You can find most of the proteins on our site.

    Function Related Protein
    UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity RC3H2,MARCH9,HERC2,TRIM71,MUL1A,RNF169,RAG1,NEURL1B,SIAH1A,MARCH5L
    coenzyme F420-0 gamma-glutamyl ligase activity MUL1A,MYLIPB,HERC2,MARCH4,MARCH6,LTN1,MARCH9,SHRPRBCK1R,MYLIPA,NEURL1B
    coenzyme F420-2 alpha-glutamyl ligase activity MARCH9,UBE2IA,RNF144AA,UBR1,SIAH1A,RC3H2,RNF149,MUL1A,SIAH2L,ITCHA
    protein-glycine ligase activity RNF187,TMEM129,MARCH4,TRIM71,RNF144AA,MARCH11,SHRPRBCK1R,RNF144AB,SIAH1A,MARCH9
    ligase activity UBE2IB,HECTD2,MARCH1,TRIM71,NAPRT1,MID1,UBR5,RNF115,HECW1,TRIM17
    protein-glycine ligase activity, initiating NEURL3,ARIH1L,TRIM41,UBE2IB,DTX1,RNF187,SHRPRBCK1R,LTN1,UBR1,RNF149
    protein-glutamic acid ligase activity RAG1,RNF149,RNF169,MARCH4,TRIM71,NEURL3,MYLIPA,RNF180,MYLIPB,LTN1
    metal ion binding STEAP1,SMYD2A,BTR16,CPPED1,BCO2,MLL5,ZFP771,TRIM27,TENC1,REV3L
    ribosomal S6-glutamic acid ligase activity MARCH6,TRIM41,DTX1,ZNRF3,MARCH4,RNF144AA,ZNRF2B,HECW2,RNF149,MGRN1A

    Interacting Protein

    TRIM50 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIM50 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIM50.

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