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UBN1

Official Full Name

ubinuclein 1
Synonyms

UBN1; ubinuclein 1; ubinuclein-1; HIRA-binding protein; ubiquitously expressed nuclear protein; VT; VT4;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Rhesus Macaque
Zebrafish

Source

E.coli
HEK293
Mammalian Cell

Tag

GST
His
His (Fc)
Avi

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	UBN1-301479H	Recombinant Human UBN1 protein, GST-tagged	E.coli	GST	Met592-His791	Inquiry
Mouse	UBN1-17751M	Recombinant Mouse UBN1 Protein	Mammalian Cell	His		Inquiry
Mouse	UBN1-9853M	Recombinant Mouse UBN1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	UBN1-9853M-B	Recombinant Mouse UBN1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rhesus Macaque	UBN1-5078R	Recombinant Rhesus monkey UBN1 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	UBN1-4891R	Recombinant Rhesus Macaque UBN1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rhesus Macaque	UBN1-4891R-B	Recombinant Rhesus Macaque UBN1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	UBN1-5993Z	Recombinant Zebrafish UBN1	Mammalian Cell	His		Inquiry
Chicken	UBN1-3551C	Recombinant Chicken UBN1	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
UBN1 Related Articles

UBN1 involved in several pathways and played different roles in them. We selected most pathways UBN1 participated on our site, such as Cellular Senescence, Cellular responses to stress, DNA Damage/Telomere Stress Induced Senescence, which may be useful for your reference. Also, other proteins which involved in the same pathway with UBN1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Cellular Senescence	CDKN2A;E2F2;CDK4;HIST1H1C;EHMT2;KDM6B;UBN1;H1F0;CDKN2D
Cellular responses to stress	HIST3H2BB;PHC2;CDKN2C;MINK1;AMBRA1B;CABIN1;WIPI2;CBX4;HIST1H1E
DNA Damage/Telomere Stress Induced Senescence	EP400;HMGA1;HTATIP;POT1;POT1A;ASF1A;HIST1H1B;HIST1H1C;ACD
Formation of Senescence-Associated Heterochromatin Foci (SAHF)	HIRA;CABIN1;HIST1H1D;HIST1H1C;H1F0;HMGA1B;ASF1A;HIST1H1B;UBN1

UBN1 has several biochemical functions, for example, DNA binding, transcription factor activity, sequence-specific DNA binding, transcription factor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by UBN1 itself. We selected most functions UBN1 had, and list some proteins which have the same functions with UBN1. You can find most of the proteins on our site.

Function	Related Protein
DNA binding	ID2B;PRKRIR;NR0B2;MKXB;ZFP541;JARID2B;PURBA;ZNF367;EVE1
transcription factor activity, sequence-specific DNA binding	RUNX2A;POU3F1;FOXE1;IRF3;FOXQ2;TRIM22;HMGA1B;HOXC4;ETV6
transcription factor binding	CEBPA;FOXA2;KCNA3;TRIB1;NCOR2;PURA;KEAP1;MED12L;ARRB1

UBN1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UBN1 here. Most of them are supplied by our site. Hope this information will be useful for your research of UBN1.

Ywhae

Pchelintsev, NA; McBryan, T; et al. Placing the HIRA Histone Chaperone Complex in the Chromatin Landscape. CELL REPORTS 3:1012-1019(2013).

Tang, Y; Puri, A; et al. Identification of an Ubinuclein 1 Region Required for Stability and Function of the Human HIRA/UBN1/CABIN1/ASF1a Histone H3.3 Chaperone Complex. BIOCHEMISTRY 51:2366-2377(2012).