UGGT1

  • Official Full Name

    UDP-glucose glycoprotein glucosyltransferase 1
  • Overview

    enzyme that catalyzes the addition of a glucose residue from UDP-glucose to an N -linked Man(9)GlcNAc(2)oligosaccharide
  • Synonyms

    UGGT1;UDP-glucose glycoprotein glucosyltransferase 1;UDP glucose ceramide glucosyltransferase like 1 , UGCGL1;UDP-glucose:glycoprotein glucosyltransferase 1;HUGT1;UDP--Glc:glycoprotein glucosyltransferase;UDP-glucose ceramide glucosyltransferase-lik

Recombinant Proteins

  • Mouse
  • Zebrafish
  • Rat
  • Human
  • Mammalian Cells
  • E.coli
  • HEK293
  • His
  • T7
  • GST
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
UGGT1-17801M Recombinant Mouse UGGT1 Protein Mammalian Cells Mouse His
UGGT1-4747Z Recombinant Zebrafish UGGT1 Mammalian Cells Zebrafish His
UGGT1-6431R Recombinant Rat UGGT1 Protein Mammalian Cells Rat His
UGGT1-1651H Recombinant Human UGGT1 protein, His & T7-tagged E.coli Human His&T7 Leu1221~Leu1536
UGGT1-5743H Recombinant Human UGGT1 protein, GST-tagged E.coli Human GST 1221-1531 aa
UGGT1-5744H Recombinant Human UGGT1 protein, His-tagged E.coli Human His 1221-1531 aa
UGGT1-6032H Recombinant Human UGGT1 Protein (Leu1221-Leu1536), N-His tagged E.coli Human His Leu1221-Leu1536
UGGT1-6087R Recombinant Rat UGGT1 Protein, His (Fc)-Avi-tagged HEK293 Rat Avi&Fc&His
UGGT1-6087R-B Recombinant Rat UGGT1 Protein Pre-coupled Magnetic Beads HEK293 Rat
UGGT1-9883M Recombinant Mouse UGGT1 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
UGGT1-9883M-B Recombinant Mouse UGGT1 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    UGGT1 involved in several pathways and played different roles in them. We selected most pathways UGGT1 participated on our site, such as Protein processing in endoplasmic reticulum, which may be useful for your reference. Also, other proteins which involved in the same pathway with UGGT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Protein processing in endoplasmic reticulum MAPK8,RBX1,DNAJC3,PDIA6,ERN1,RAD23AA,MAPK8A,WFS1,HSPA8,SSR3

    Protein Function

    UGGT1 has several biochemical functions, for example, 1,2-dihydroxy-phenanthrene glycosyltransferase activity,1-phenanthrol glycosyltransferase activity,9-phenanthrol UDP-glucuronosyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by UGGT1 itself. We selected most functions UGGT1 had, and list some proteins which have the same functions with UGGT1. You can find most of the proteins on our site.

    Function Related Protein
    salicylic acid glucosyltransferase (glucoside-forming) activity GTDC2,DPY19L1,PIGB,GLT8D1,B3GNT8,B3GNT9-PS,B3GNTL1,POMGNT2,GALNTL4,4931440L10Rik
    glycolipid mannosyltransferase activity GALNTL4,4931440L10Rik,GALNT18A,POC1BL,GTDC2,DPY19L4,PIGB,B3GNT9-PS,B3GNTL1,B3GNT8
    unfolded protein binding PFDN2,NPM1,HSPE1,DNAJA3A,SRSF12,CALRL2,TBCA,CCT6B,CCDC102A,HSP90AA1.1
    inositol phosphoceramide synthase activity GALNT18A,GALNTL4,POC1BL,B3GNTL1,DPY19L1,B3GNT8,GTDC2,GLT8D1,B3GNT9-PS,DPY19L4
    transferase activity, transferring glycosyl groups GXYLT1B,GXYLT2,UGT1A2,C1GALT1B,GALNTL4,UGT1B5,UGT2B6,FT1,C1GALT1A,UGT1B7
    alpha-1,3-galactosyltransferase activity GALNTL4,GLT8D1,GTDC2,DPY19L4,DPY19L1,B3GNTL1,GALNT18A,A3GALT2,PIGB,POMGNT2
    lipopolysaccharide-1,6-galactosyltransferase activity B3GNT8,DPY19L1,4931440L10Rik,GTDC2,PIGB,POC1BL,B3GNTL1,GALNTL4,POMGNT2,GLT8D1
    cytokinin 9-beta-glucosyltransferase activity GTDC2,GALNTL4,GALNT18A,DPY19L4,DPY19L1,GLT8D1,POMGNT2,B3GNTL1,B3GNT8,B3GNT9-PS
    alpha-1,6-mannosyltransferase activity DPY19L4,4931440L10Rik,POMGNT2,GLT8D1,B3GNT8,GALNTL4,PIGB,B3GNT9-PS,GTDC2,B3GNTL1

    Interacting Protein

    UGGT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UGGT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of UGGT1.

    Resources

    References

    • Takeda, Y; Seko, A; et al. Functional Analysis of Endoplasmic Reticulum Glucosyltransferase (UGGT) Using Synthetic Glycans. TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY 26:107-118(2014).
    • Daikoku, S; Seko, A; et al. Glycan structure and site of glycosylation in the ER-resident glycoprotein, uridine 5 '-diphosphate-glucose: glycoprotein glucosyltransferases 1 from rat, porcine, bovine, and human. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 451:356-360(2014).

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