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Official Full Name unc-13 homolog D
Background This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.
Synonyms UNC13D; unc-13 homolog D (C. elegans); protein unc-13 homolog D; Munc13 4; FHL3; HLH3; HPLH3; Munc13-4
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E. coli
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human UNC13D-28544TH Recombinant Human UNC13D, His-tagged E.coli His
    Human UNC13D-285H Recombinant Human UNC13D protein, His-tagged E. coli His
    Human UNC13D-501HCL Recombinant Human UNC13D 293 Cell Lysate HEK293 N/A
    Human UNC13D-6204H Recombinant Human UNC13D Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse UNC13D-17843M Recombinant Mouse UNC13D Protein Mammalian Cell His
    Mouse Unc13d-6836M Recombinant Mouse Unc13d Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Rat UNC13D-6447R Recombinant Rat UNC13D Protein Mammalian Cell His

    unc13d involved in several pathways and played different roles in them. We selected most pathways unc13d participated on our site, such as Deregulation of Rab and Rab Effector Genes in Bladder Cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with unc13d were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Deregulation of Rab and Rab Effector Genes in Bladder Cancer RPH3AL; MLPH; SYTL2; RPH3A; MYRIP; GCC2; TBC1D10A; EXPH5; SYTL3; UNC13D

    unc13d has several biochemical functions, for example, Rab GTPase binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by unc13d itself. We selected most functions unc13d had, and list some proteins which have the same functions with unc13d. You can find most of the proteins on our site.

    Function Related Protein
    Rab GTPase binding MYRIP; SGSM2; SYTL1; LLGL1; STXBP5A; MICALL2; Fert2; ANKRD27; CCDC64; ULK1
    protein binding C18orf56; RAET1D; IL11; BDKRB2; SRI; CPNE7; ZBTB24; G6PD; MRPL10; L3MBTL2

    unc13d has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with unc13d here. Most of them are supplied by our site. Hope this information will be useful for your research of unc13d.

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