• Official Full Name

    ubiquitin specific peptidase 11

  • Background

    Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional;activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and;deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that;specifically cleave ubiquitin from ubiquitin-conjugated protein substrates. This gene encodes a deubiquitinating;enzyme which lies in a gene cluster on chromosome Xp11.23.
  • Synonyms

    USP11; ubiquitin specific peptidase 11; ubiquitin specific protease 11; ubiquitin carboxyl-terminal hydrolase 11; UHX1; ubiquitin thioesterase 11; deubiquitinating enzyme 11; ubiquitin thiolesterase 11; ubiquitin-specific processing protease 11; ubiquitin;
    • Type:
    • Recombinant Proteins
    • Species :
    • Human
    • Source :
    • Insect Cell
    • Tag :
    • GST
    • His
    • No tag
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human USP11-08H Active Recombinant Human USP11 protein, His-tagged Insect Cell His
    Human USP11-0886H Recombinant Human USP11 Protein (A2-N963), Tag Free Insect Cell No tag
    Human USP11-360H Recombinant Human USP11 Protein, GST-tagged Insect Cell GST
    Human USP11-0885H Recombinant Human USP11 Protein (A2-N963), GST tagged Insect Cell GST
    • USP11 Related Articles
    • USP11 Related Research Area
    Kaasinen, E; Rahikkala, E; et al. Clinical characterization, genetic mapping and whole- genome sequence analysis of a novel autosomal recessive intellectual disability syndrome. EUROPEAN JOURNAL OF MEDICAL GENETICS 57:543-551(2014).
    Burkhart, RA; Peng, Y; et al. Mitoxantrone Targets Human Ubiquitin-Specific Peptidase 11 (USP11) and Is a Potent Inhibitor of Pancreatic Cancer Cell Survival. MOLECULAR CANCER RESEARCH 11:901-911(2013).
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