USP11
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Official Full Name
ubiquitin specific peptidase 11
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Background
Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional;activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and;deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that;specifically cleave ubiquitin from ubiquitin-conjugated protein substrates. This gene encodes a deubiquitinating;enzyme which lies in a gene cluster on chromosome Xp11.23. -
Synonyms
USP11; ubiquitin specific peptidase 11; ubiquitin specific protease 11; ubiquitin carboxyl-terminal hydrolase 11; UHX1; ubiquitin thioesterase 11; deubiquitinating enzyme 11; ubiquitin thiolesterase 11; ubiquitin-specific processing protease 11; ubiquitin;
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | USP11-08H | Active Recombinant Human USP11 protein, His-tagged | Insect Cell | His |
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Human | USP11-0886H | Recombinant Human USP11 Protein (A2-N963), Tag Free | Insect Cell | No tag |
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Human | USP11-360H | Recombinant Human USP11 Protein, GST-tagged | Insect Cell | GST |
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Human | USP11-0885H | Recombinant Human USP11 Protein (A2-N963), GST tagged | Insect Cell | GST |
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- USP11 Related Articles
- USP11 Related Research Area
Kaasinen, E; Rahikkala, E; et al. Clinical characterization, genetic mapping and whole- genome sequence analysis of a novel autosomal recessive intellectual disability syndrome. EUROPEAN JOURNAL OF MEDICAL GENETICS 57:543-551(2014).
Burkhart, RA; Peng, Y; et al. Mitoxantrone Targets Human Ubiquitin-Specific Peptidase 11 (USP11) and Is a Potent Inhibitor of Pancreatic Cancer Cell Survival. MOLECULAR CANCER RESEARCH 11:901-911(2013).
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