VPS18

  • Official Full Name

    vacuolar protein sorting 18 homolog (S. cerevisiae)

  • Overview

    Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps18 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway.
  • Synonyms

    VPS18; vacuolar protein sorting 18 homolog (S. cerevisiae); vacuolar protein sorting protein 18; vacuolar protein sorting-associated protein 18 homolog; KIAA1475; PEP3; hVPS18; Vacuolar protein sorting 18; OTTHUMP00000160630;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Rhesus Macaque
  • Zebrafish
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human VPS18-397HCL Recombinant Human VPS18 293 Cell Lysate HEK293 N/A
Rhesus Macaque VPS18-5166R Recombinant Rhesus monkey VPS18 Protein, His-tagged Mammalian Cell His
Rhesus Macaque VPS18-4979R Recombinant Rhesus Macaque VPS18 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque VPS18-4979R-B Recombinant Rhesus Macaque VPS18 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish VPS18-9519Z Recombinant Zebrafish VPS18 Mammalian Cell His
Chicken VPS18-4445C Recombinant Chicken VPS18 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • VPS18 Related Articles

VPS18 involved in several pathways and played different roles in them. We selected most pathways VPS18 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with VPS18 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

VPS18 has several biochemical functions, for example, actin binding, metal ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by VPS18 itself. We selected most functions VPS18 had, and list some proteins which have the same functions with VPS18. You can find most of the proteins on our site.

Function Related Protein
actin bindingMYO1F;CCR5;MYHZ1.2;CAPZA2;HIP1R;MYOT;MAEA;NRAP;EPB41
metal ion bindingANKZF1;PPP4C;ZNF182;GFI1AA;PHOSPHO1;INPP5B;ANKMY2;ZNF45L;NUDT14
protein bindingMALSU1;PYDC1;SPRR2A;SERPINA3K;ANKHD1;ATP7A;LMNA;ACTR10;RTKN
protein binding, bridgingPPP2R3A;CSTA;FGG;FSCN1;CUX1;CBX5;FKBP4;FBXW7;IVL
syntaxin bindingCPLX2L;RPH3A;HECTD3;VAMP7;CPLX2;VPS11;CAV1;DOC2D;SYT11A

VPS18 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VPS18 here. Most of them are supplied by our site. Hope this information will be useful for your research of VPS18.

VPS16; VPS11

Sato, TK; Rehling, P; et al. Class C Vps protein complex regulates vacuolar SNARE pairing and is required for vesicle docking/fusion. MOLECULAR CELL 6:661-671(2000).
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