VPS25

  • Official Full Name

    vacuolar protein sorting 25 homolog

  • Background

    VPS25, VPS36 (MIM 610903), and SNF8 (MIM 610904) form ESCRT-II (endosomal sorting complex required for transport II), a;complex involved in endocytosis of ubiquitinated membrane proteins. VPS25, VPS36, and SNF8 are also associated in a;multiprotein complex with RNA polymerase II elongation factor (ELL; MIM 600284) (Slagsvold et al., 2005 (PubMed;15755741); Kamura et al., 2001 (PubMed 11278625)).
  • Synonyms

    VPS25; vacuolar protein sorting 25 homolog (S. cerevisiae); vacuolar protein sorting 25 (yeast); vacuolar protein-sorting-associated protein 25; DERP9; EAP20; MGC10540; ESCRT-II complex subunit VPS25; ELL-associated protein of 20 kDa; dermal papilla-deriv;
    • Type:
    • Recombinant Proteins
    • Cell & Tissue Lysates
    • Protein Pre-coupled Magnetic Beads
    • Species :
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • In Vitro Cell Free System
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • His (Fc)
    • Avi
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human VPS25-6255HF Recombinant Full Length Human VPS25 Protein, GST-tagged In Vitro Cell Free System GST
    Human VPS25-3672H Recombinant Human VPS25, His-tagged E.coli His
    Human VPS25-395HCL Recombinant Human VPS25 293 Cell Lysate HEK293 N/A
    Human VPS25-4361H Recombinant Human VPS25 Protein, GST-tagged Wheat Germ GST
    Mouse VPS25-18365M Recombinant Mouse VPS25 Protein Mammalian Cell His
    Mouse Vps25-6931M Recombinant Mouse Vps25 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse VPS25-10060M Recombinant Mouse VPS25 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Mouse VPS25-10060M-B Recombinant Mouse VPS25 Protein Pre-coupled Magnetic Beads HEK293
    Rat VPS25-6196R Recombinant Rat VPS25 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Rat VPS25-6196R-B Recombinant Rat VPS25 Protein Pre-coupled Magnetic Beads HEK293
    Rat VPS25-6540R Recombinant Rat VPS25 Protein Mammalian Cell His
    Zebrafish VPS25-5515Z Recombinant Zebrafish VPS25 Mammalian Cell His
    • Involved Pathway
    • Protein Function
    • Interacting Protein

    VPS25 involved in several pathways and played different roles in them. We selected most pathways VPS25 participated on our site, such as Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with VPS25 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    EndocytosisPIP5K1B;CYTH4;PIP5K1AB;MVB12B;EHD1A;SPG21;GRK7A;DNM1B;LDLRAP1B

    VPS25 has several biochemical functions, for example, protein N-terminus binding, protein binding, protein homodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by VPS25 itself. We selected most functions VPS25 had, and list some proteins which have the same functions with VPS25. You can find most of the proteins on our site.

    Function Related Protein
    protein N-terminus bindingSTX1A;HAX1;KCNB1;SMARCE1;YWHAQ;SNCA;TGFB1;DCTN4;RPS21
    protein bindingCD58;ATP6V0C;TSC22D1;SEMA4D;PDK3;TRAF3;FAM96A;Akap3;EXOSC5
    protein homodimerization activityID1;DMRT3A;DAPK3;FAM109A;ZBTB4;C16orf89;TPD52;CCBL1;VPS24
    structural molecule activityNEFLB;ROCK2;CLDN3;CLDN23;FGG;CLDN7A;KRT6A;SNTG1;CLDNC

    VPS25 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VPS25 here. Most of them are supplied by our site. Hope this information will be useful for your research of VPS25.

    SNF8; TRIM27; REL; BEND5; CRLF3; uvrB

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