VPS26A

  • Official Full Name

    vacuolar protein sorting 26 homolog A (S. pombe)

  • Background

    This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Synonyms

    VPS26A; vacuolar protein sorting 26 homolog A (S. pombe); HB58; PEP8A; VPS26; Hbeta58; vacuolar protein sorting-associated protein 26A; vesicle protein sorting 26A;
    • Type:
    • Recombinant Proteins
    • Cell & Tissue Lysates
    • Protein Pre-coupled Magnetic Beads
    • Species :
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • C
    • Myc
    • DDK
    • His
    • His (Fc)
    • Avi
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human VPS26A-6954H Recombinant Human Vacuolar Protein Sorting 26 Homolog A (S. pombe), His-tagged E.coli His
    Human VPS26A-394HCL Recombinant Human VPS26A 293 Cell Lysate HEK293 N/A
    Human VPS26A-2342H Recombinant Human VPS26A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Human VPS26A-200H Recombinant Human VPS26A Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
    Human VPS26A-3673H Recombinant Human VPS26A, His-tagged E.coli His
    Human VPS26A-2342H-B Recombinant Human VPS26A Protein Pre-coupled Magnetic Beads HEK293
    Mouse VPS26A-18366M Recombinant Mouse VPS26A Protein Mammalian Cell His
    Mouse VPS26A-10061M-B Recombinant Mouse VPS26A Protein Pre-coupled Magnetic Beads HEK293
    Mouse Vps26a-6932M Recombinant Mouse Vps26a Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse VPS26A-10061M Recombinant Mouse VPS26A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Rat VPS26A-6541R Recombinant Rat VPS26A Protein Mammalian Cell His
    Rat VPS26A-6197R-B Recombinant Rat VPS26A Protein Pre-coupled Magnetic Beads HEK293
    Rat VPS26A-6197R Recombinant Rat VPS26A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Rhesus Macaque VPS26A-4980R Recombinant Rhesus Macaque VPS26A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Rhesus Macaque VPS26A-5167R Recombinant Rhesus monkey VPS26A Protein, His-tagged Mammalian Cell His
    Rhesus Macaque VPS26A-4980R-B Recombinant Rhesus Macaque VPS26A Protein Pre-coupled Magnetic Beads HEK293
    Zebrafish VPS26A-11149Z Recombinant Zebrafish VPS26A Mammalian Cell His
    • Involved Pathway
    • Protein Function
    • Interacting Protein

    VPS26A involved in several pathways and played different roles in them. We selected most pathways VPS26A participated on our site, such as Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with VPS26A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    EndocytosisHSPA8;SH3GLB2B;CHMP2BB;ZFYVE16;WASH1;PSD4;EHD1A;DAB2;CLTCB

    VPS26A has several biochemical functions, for example, protein binding, protein transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by VPS26A itself. We selected most functions VPS26A had, and list some proteins which have the same functions with VPS26A. You can find most of the proteins on our site.

    Function Related Protein
    protein bindingNOXA1;ITPKB;PSMC6;TARSL2;E2F1;CDC25B;DHH;CDKN2D;Tnfrsf23
    protein transporter activityKPNB1;AP1S3B;CCT6B;AP2A2;XPO6;XPO1;XPO5;COG3;KPNA5

    VPS26A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VPS26A here. Most of them are supplied by our site. Hope this information will be useful for your research of VPS26A.

    VPS35; VPS29; SNX2; SNX1; ILK; SMYD2; IGF2R

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