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WAC

Official Full Name

WW domain containing adaptor with coiled-coil
Overview

The protein encoded by this gene contains a WW domain, which is a protein module found in a wide range of signaling proteins. This domain mediates protein-protein interactions and binds proteins containing short linear peptide motifs that are proline-rich or contain at least one proline. This gene product shares 94% sequence identity with the WAC protein in mouse, however, its exact function is not known. Alternative splicing results in multiple transcript variants.
Synonyms

WAC; WW domain containing adaptor with coiled-coil; WW domain containing adaptor with coiled coil; WW domain-containing adapter protein with coiled-coil; BM 016; FLJ31290; MGC10753; PRO1741; Wwp4; 1110067P07Rik; BA48B24; BA48B24.1; KIAA1844; OTTHUMP00000019380; OTTHUMP00000019382; WAC_HUMAN; WW domain containing adapter protein with coiled coil; BM-016;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	WAC-371HCL	Recombinant Human WAC 293 Cell Lysate	HEK293	N/A		Inquiry
Mouse	WAC-18421M	Recombinant Mouse WAC Protein	Mammalian Cell	His		Inquiry
Mouse	WAC-10102M	Recombinant Mouse WAC Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	WAC-10102M-B	Recombinant Mouse WAC Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Enterobacteria Phage T4	WAC-2065E	Recombinant Enterobacteria Phage T4 WAC Protein (2-487 aa), His-SUMO-tagged	E.coli	His/SUMO	2-487 aa	Inquiry

Involved Pathway
Protein Function
Interacting Protein
WAC Related Articles

WAC involved in several pathways and played different roles in them. We selected most pathways WAC participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with WAC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

WAC has several biochemical functions, for example, RNA polymerase II core binding, chromatin binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by WAC itself. We selected most functions WAC had, and list some proteins which have the same functions with WAC. You can find most of the proteins on our site.

Function	Related Protein
RNA polymerase II core binding	SMYD3;CTR9;SMYD2;SMYD2A;KIAA1530;WAC;GTF2E1;KIAA1967;AGO1
chromatin binding	HDAC7;ELK1;CDK9;RNF168;WDHD1;ARX;PRIMPOL;BARX2;ATF2
protein binding	HIP1;DAB2;PRKAR1A;PINX1;NCK1;CHMP1B;UBL5;SPATA8;TGFBR3

WAC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with WAC here. Most of them are supplied by our site. Hope this information will be useful for your research of WAC.

KRT15; 147700; TRAF1; NFE2L2; MTUS2; KLC3; SYTL5

D'Souza, LS; Payette, MJ; et al. Estimated cost efficacy of systemic treatments that are approved by the US Food and Drug Administration for the treatment of moderate to severe psoriasis. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY 72:589-598(2015).

Bergstrom, M; Astrom, E; et al. Elucidating the selectivity of recombinant forms of Aleuria aurantia lectin using weak affinity chromatography. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES 885:66-72(2012).