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WDR36

Official Full Name

WD repeat domain 36
Overview

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Mutations in this gene have been associated with adult-onset primary open-angle glaucoma (POAG).
Synonyms

WDR36; WD repeat domain 36; WD repeat-containing protein 36; DKFZp686I1650; GLC 1G; GLC1G; T cell activation WD repeat containing protein; T cell activation WD repeat protein; TA WDRP; TAWDRP; UTP 21; UTP21; WD repeat containing protein 36; WDR 36; OTTHUMP00000158997; OTTHUMP00000223962; OTTHUMP00000223963; T-cell activation WD repeat protein; T-cell activation WD repeat-containing protein; TA-WDRP;

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	WDR36-351HCL	Recombinant Human WDR36 293 Cell Lysate	HEK293	Non	Inquiry
Human	WDR36-5330H	Recombinant Human WDR36 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc&DDK	Inquiry
Mouse	Wdr36-6978M	Recombinant Mouse Wdr36 Protein, Myc/DDK-tagged	HEK293T	Myc&DDK	Inquiry
Zebrafish	WDR36-9969Z	Recombinant Zebrafish WDR36	Mammalian Cell	His	Inquiry
Chicken	WDR36-3426C	Recombinant Chicken WDR36	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

WDR36 involved in several pathways and played different roles in them. We selected most pathways WDR36 participated on our site, such as Ribosome biogenesis in eukaryotes, which may be useful for your reference. Also, other proteins which involved in the same pathway with WDR36 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Ribosome biogenesis in eukaryotes	NXT2;LOC81691;NOP58;REXO1;PWP2;ACK2;POP5;RPP38;XPO1

WDR36 has several biochemical functions, for example, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by WDR36 itself. We selected most functions WDR36 had, and list some proteins which have the same functions with WDR36. You can find most of the proteins on our site.

Function	Related Protein
poly(A) RNA binding	HDGF;HSPD1;ARCN1;NXF2;TUFM;PSMC1;RPL6;BTF3;RPL37A

WDR36 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with WDR36 here. Most of them are supplied by our site. Hope this information will be useful for your research of WDR36.

G3BP1; USP36; G3BP2; NUDC; NOP56; ESR1; VCAM1; MNDA; HDGF; HNRNPU; IFI16; HDAC11; Rrbp1; SH3GLB1; EXOSC1

Research Area

Takamoto, M; Araie, M; et al. Genetics of primary open angle glaucoma. JAPANESE JOURNAL OF OPHTHALMOLOGY 58:1-15(2014).

Li, XN; Ampleford, EJ; et al. Genome-wide association studies of asthma indicate opposite immunopathogenesis direction from autoimmune diseases. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 130:861-+(2012).