WDR82 involved in several pathways and played different roles in them. We selected most pathways WDR82 participated on our site, such as mRNA surveillance pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with WDR82 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name |
Pathway Related Protein |
| mRNA surveillance pathway |
NXF3; DAZAP1; MSI2; CPSF2; ETF1; SMG6; PPP2R2C; BCL2L2-PABPN1; PPP2R2A; PELO |
WDR82 has several biochemical functions, for example, chromatin binding, histone methyltransferase activity (H3-K4 specific). Some of the functions are cooperated with other proteins, some of the functions could acted by WDR82 itself. We selected most functions WDR82 had, and list some proteins which have the same functions with WDR82. You can find most of the proteins on our site.
| Function |
Related Protein |
| chromatin binding |
LDB1; NUP62; PHC1; SMARCD3; CRX; PRDM11; EGFR; RAN; DNAJC2; YBX2 |
| histone methyltransferase activity (H3-K4 specific) |
SETMAR; WDR82; MLL5; KMT2A; MLL1; WHSC1L1; SETD3; KMT2E; SMYD1B; ASH1L |
WDR82 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with WDR82 here. Most of them are supplied by our site. Hope this information will be useful for your research of WDR82.
Ramakrishnan, R; Liu, HB; et al. Identification of novel CDK9 and Cyclin T1-associated protein complexes (CCAPs) whose siRNA depletion enhances HIV-1 Tat function. RETROVIROLOGY 9:-(2012).
Bi, Y; Lv, Z; et al. WDR82, a Key Epigenetics-Related Factor, Plays a Crucial Role in Normal Early Embryonic Development in Mice. BIOLOGY OF REPRODUCTION 84:756-764(2011).
