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WNK3

Official Full Name

WNK lysine deficient protein kinase 3
Overview

This gene encodes a protein belonging to the with no lysine family of serine-threonine protein kinases. These family members lack the catalytic lysine in subdomain II, and instead have a conserved lysine in subdomain I. This family member functions as a positive regulator of the transcellular Ca2+ transport pathway, and it plays a role in the increase of cell survival in a caspase-3-dependent pathway. Alternative splicing results in multiple transcript variants.
Synonyms

WNK3; WNK lysine deficient protein kinase 3; PRKWNK3, protein kinase, lysine deficient 3; serine/threonine-protein kinase WNK3; protein kinase with no lysine 3; PRKWNK3; FLJ30437; FLJ42662; KIAA1566;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	WNK3-260H	Active Recombinant Human WNK3(1-434) Protein, N-His-tagged	Sf21	His	1-434 aa	Inquiry

WNK3 Related Articles

WNK3 involved in several pathways and played different roles in them. We selected most pathways WNK3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with WNK3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

WNK3 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by WNK3 itself. We selected most functions WNK3 had, and list some proteins which have the same functions with WNK3. You can find most of the proteins on our site.

Function	Related Protein

WNK3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with WNK3 here. Most of them are supplied by our site. Hope this information will be useful for your research of WNK3.

Lai, JG; Tsai, SM; et al. Zebrafish WNK Lysine Deficient Protein Kinase 1 (wnk1) Affects Angiogenesis Associated with VEGF Signaling. PLOS ONE 9:-(2014).

de los Heros, P; Alessi, DR; et al. The WNK-regulated SPAK/OSR1 kinases directly phosphorylate and inhibit the K+-Cl- co-transporters. BIOCHEMICAL JOURNAL 458:559-573(2014).